Soluble amyloid-β precursor peptide does not regulate GABA


Journal

eLife
ISSN: 2050-084X
Titre abrégé: Elife
Pays: England
ID NLM: 101579614

Informations de publication

Date de publication:
23 01 2023
Historique:
received: 21 07 2022
accepted: 22 01 2023
pubmed: 24 1 2023
medline: 15 2 2023
entrez: 23 1 2023
Statut: epublish

Résumé

Amyloid-β precursor protein (APP) regulates neuronal activity through the release of secreted APP (sAPP) acting at cell surface receptors. APP and sAPP were reported to bind to the extracellular sushi domain 1 (SD1) of GABA

Identifiants

pubmed: 36688536
doi: 10.7554/eLife.82082
pii: 82082
pmc: PMC9917443
doi:
pii:

Substances chimiques

Amyloid beta-Peptides 0
Amyloid beta-Protein Precursor 0
Neurotransmitter Agents 0
gamma-Aminobutyric Acid 56-12-2

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Swiss National Science Foundation
ID : 31003A-152970
Pays : Switzerland

Informations de copyright

© 2023, Rem et al.

Déclaration de conflit d'intérêts

PR, VS, DF, SR, DU, TF, LT, SR, ZC, PR, JP, JS, BF, MG, TB No competing interests declared, KS is a co-founder and a part time employee of Avilex Pharma, BB is a member of the scientific advisory board of Addex Therapeutics, Geneva

Références

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):16916-21
pubmed: 17942691
Molecules. 2020 Jul 07;25(13):
pubmed: 32646032
J Biol Chem. 2009 Oct 16;284(42):29136-45
pubmed: 19648112
Cell Chem Biol. 2017 Mar 16;24(3):360-370
pubmed: 28286129
J Biol Chem. 2013 Aug 23;288(34):24848-56
pubmed: 23843457
Cells. 2019 Jun 06;8(6):
pubmed: 31174368
J Neurosci. 2001 Feb 15;21(4):1189-202
pubmed: 11160389
Mol Pharmacol. 2000 Mar;57(3):419-26
pubmed: 10692480
Nat Rev Neurosci. 2019 Mar;20(3):129
pubmed: 30733610
Nat Neurosci. 2016 Feb;19(2):233-42
pubmed: 26691831
Curr Opin Neurobiol. 2017 Aug;45:16-23
pubmed: 28282540
Trends Pharmacol Sci. 2021 Apr;42(4):283-299
pubmed: 33581873
Neuron. 2015 Mar 04;85(5):942-58
pubmed: 25741722
Biochem Pharmacol. 2014 Oct 1;91(3):369-79
pubmed: 25065880
Sci Adv. 2021 May 28;7(22):
pubmed: 34049877
Nat Commun. 2019 Mar 22;10(1):1331
pubmed: 30902970
NMR Biomed. 2014 Mar;27(3):291-303
pubmed: 24449532
Nature. 2021 Jun;594(7864):594-598
pubmed: 33911284
Neuroreport. 1997 Jul 7;8(9-10):2133-7
pubmed: 9243598
Am J Hum Genet. 2022 Oct 6;109(10):1885-1893
pubmed: 36103875
Acta Neuropathol. 2015 Jan;129(1):21-37
pubmed: 25432317
Nature. 2020 Aug;584(7820):310-314
pubmed: 32580208
Science. 2019 Jan 11;363(6423):123-124
pubmed: 30630916
Curr Chem Genomics. 2010 Dec 21;4:84-91
pubmed: 21331312
J Comp Neurol. 1999 Sep 13;412(1):1-16
pubmed: 10440706
J Neurochem. 2015 Oct;135(1):88-100
pubmed: 26212383
Nature. 2020 Aug;584(7820):304-309
pubmed: 32581365
Eur J Pharmacol. 1990 Oct 2;187(1):27-38
pubmed: 2176979
Cell Res. 2020 Jul;30(7):564-573
pubmed: 32494023
Nat Rev Neurosci. 2010 May;11(5):301-15
pubmed: 20389305
Biomed Eng Online. 2003 May 17;2:13
pubmed: 12801419
Neuropharmacology. 2021 Jun 1;190:108426
pubmed: 33279506
Prog Neurobiol. 2020 Nov;194:101801
pubmed: 32428558
Nature. 2020 Aug;584(7820):298-303
pubmed: 32555460
Mol Pharmacol. 2002 May;61(5):1070-80
pubmed: 11961124
Neuropharmacology. 2015 Jan;88:145-54
pubmed: 25196734
Neurobiol Dis. 2008 Aug;31(2):250-60
pubmed: 18585048
Nature. 1998 Dec 17;396(6712):683-7
pubmed: 9872317
Nature. 1993 May 20;363(6426):274-6
pubmed: 8387644
Genesis. 2006 Dec;44(12):611-21
pubmed: 17146780
Nat Rev Neurosci. 2017 May;18(5):281-298
pubmed: 28360418
Chem Sci. 2021 Mar 16;12(17):6107-6116
pubmed: 33996007
Neuropharmacology. 1999 Mar;38(3):349-59
pubmed: 10219973
Neuron. 2014 Jun 4;82(5):1032-44
pubmed: 24836506
Mol Cell Neurosci. 1997;9(3):194-206
pubmed: 9245502
Neurobiol Learn Mem. 2004 Jan;81(1):27-38
pubmed: 14670356
Neuron. 2019 Feb 20;101(4):557-559
pubmed: 30790537
Neurosci Lett. 2009 Aug 21;460(1):92-6
pubmed: 19463893
BMC Genomics. 2011 Mar 24;12:160
pubmed: 21435241
J Neurosci. 2014 Jun 11;34(24):8336-46
pubmed: 24920637
J Neurophysiol. 2017 Mar 1;117(3):885-902
pubmed: 27903638
Phys Chem Chem Phys. 2022 May 25;24(20):12267-12280
pubmed: 35543350
Nature. 2016 Dec 1;540(7631):60-68
pubmed: 27905440
Neuron. 2006 May 18;50(4):589-601
pubmed: 16701209
Nat Rev Neurosci. 2012 May 18;13(6):380-94
pubmed: 22595784
Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12171-6
pubmed: 22778417
Neuron. 2001 Jul 19;31(1):47-58
pubmed: 11498050
Science. 2019 Jan 11;363(6423):
pubmed: 30630900
EMBO J. 2018 Jun 1;37(11):
pubmed: 29661886

Auteurs

Pascal Dominic Rem (PD)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Vita Sereikaite (V)

Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken, Copenhagen, Denmark.

Diego Fernández-Fernández (D)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Sebastian Reinartz (S)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Daniel Ulrich (D)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Thorsten Fritzius (T)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Luca Trovo (L)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Salomé Roux (S)

Institut de Génomique Fonctionnelle, Université de Montpellier, Montpellier, France.

Ziyang Chen (Z)

Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken, Copenhagen, Denmark.

Philippe Rondard (P)

Institut de Génomique Fonctionnelle, Université de Montpellier, Montpellier, France.

Jean-Philippe Pin (JP)

Institut de Génomique Fonctionnelle, Université de Montpellier, Montpellier, France.

Jochen Schwenk (J)

Institute of Physiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Bernd Fakler (B)

Institute of Physiology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
CIBSS Center for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.
Center for Basics in NeuroModulation, Freiburg, Germany.

Martin Gassmann (M)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Tania Rinaldi Barkat (TR)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

Kristian Strømgaard (K)

Center for Biopharmaceuticals, Department of Drug Design and Pharmacology, University of Copenhagen, Universitetsparken, Copenhagen, Denmark.

Bernhard Bettler (B)

Department of Biomedicine, Pharmazentrum, University of Basel, Basel, Switzerland.

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Classifications MeSH