Peak Width of Skeletonized Mean Diffusivity: A Neuroimaging Marker for White Matter Injury.

Humans Aged White Matter / diagnostic imaging Diffusion Magnetic Resonance Imaging / methods Neuroimaging / adverse effects Diffusion Tensor Imaging / methods Magnetic Resonance Imaging / adverse effects Cognitive Dysfunction / complications Cerebral Small Vessel Diseases / complications

Journal

Radiology
ISSN: 1527-1315
Titre abrégé: Radiology
Pays: United States
ID NLM: 0401260

Informations de publication

Date de publication:
03 2023
Historique:
pmc-release: 01 03 2024
pubmed: 25 1 2023
medline: 25 2 2023
entrez: 24 1 2023
Statut: ppublish

Résumé

A leading cause of white matter (WM) injury in older individuals is cerebral small vessel disease (SVD). Cerebral SVD is the most prevalent vascular contributor to cognitive impairment and dementia. Therapeutic progress for cerebral SVD and other WM disorders depends on the development and validation of neuroimaging markers suitable as outcome measures in future interventional trials. Diffusion-tensor imaging (DTI) is one of the best-suited MRI techniques for assessing the extent of WM damage in the brain. But the optimal method to analyze individual DTI data remains hindered by labor-intensive and time-consuming processes. Peak width of skeletonized mean diffusivity (PSMD), a recently developed fast, fully automated DTI marker, was designed to quantify the WM damage secondary to cerebral SVD and reflect related cognitive impairment. Despite its promising results, knowledge about PSMD is still limited in the radiologic community. This focused review provides an overview of the technical details of PSMD while synthesizing the available data on its clinical and neuroimaging associations. From a critical expert viewpoint, the authors discuss the limitations of PSMD and its current validation status as a neuroimaging marker for vascular cognitive impairment. Finally, they point out the gaps to be addressed to further advance the field.

Identifiants

DOI: 10.1148/radiol.212780 PMID: 36692402 PMC: PMC9968775
pubmed: 36692402
doi: 10.1148/radiol.212780
pmc: PMC9968775
doi:

Types de publication

Journal Article Review Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e212780

Subventions

Organisme : NIA NIH HHS
ID : P30 AG062421
Pays : United States
Organisme : NIA NIH HHS
ID : P50 AG005134
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG047975
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG026484
Pays : United States

Commentaires et corrections

Type : CommentIn

Informations de copyright

© RSNA, 2023.

Références

J Cereb Blood Flow Metab. 2016 Jan;36(1):40-54
pubmed: 25944592
Neuropsychopharmacology. 2022 Jan;47(2):580-587
pubmed: 33564103
Sci Rep. 2020 Jun 8;10(1):9210
pubmed: 32514044
Stat Methods Med Res. 2020 Sep;29(9):2520-2537
pubmed: 32292115
Curr Opin Neurol. 2021 Apr 1;34(2):246-257
pubmed: 33630769
Neurosci Lett. 2019 Feb 16;694:198-207
pubmed: 30528980
Neurobiol Aging. 2015 Feb;36(2):909-18
pubmed: 25457555
J Am Heart Assoc. 2019 Feb 5;8(3):e011288
pubmed: 30717612
Front Neurol. 2019 Feb 13;10:81
pubmed: 30814973
Hum Brain Mapp. 2021 Apr 1;42(5):1406-1415
pubmed: 33289924
Alzheimers Dement (Amst). 2019 Oct 25;11:721-729
pubmed: 31700990
Neurology. 2017 May 2;88(18):1701-1708
pubmed: 28381507
Magn Reson Imaging. 2018 Nov;53:105-111
pubmed: 30048675
Stroke. 2018 Feb;49(2):491-497
pubmed: 29335334
Lancet Glob Health. 2019 Apr;7(4):e436-e447
pubmed: 30879508
Front Neurosci. 2020 Mar 19;14:238
pubmed: 32265640
Alzheimers Dement (Amst). 2022 Mar 28;14(1):e12261
pubmed: 35382232
Neuroimage Clin. 2020;27:102280
pubmed: 32521475
Ann Neurol. 2011 Nov;70(5):764-73
pubmed: 22162059
Alzheimers Dement. 2020 Nov;16(11):1504-1514
pubmed: 32808747
Comput Struct Biotechnol J. 2020 Jun 09;18:1613-1624
pubmed: 32670502
Front Psychiatry. 2019 Jul 26;10:524
pubmed: 31402877
Neurology. 2019 Feb 26;92(9):e933-e943
pubmed: 30700595
Neurology. 2021 Feb 2;96(5):e698-e708
pubmed: 33199431
AJNR Am J Neuroradiol. 2021 May;42(5):875-881
pubmed: 33664113
NMR Biomed. 2015 Apr;28(4):468-85
pubmed: 25802212
Nat Commun. 2016 Dec 15;7:13629
pubmed: 27976682
Neuroreport. 2007 Oct 29;18(16):1735-9
pubmed: 17921878
J Neurophysiol. 2016 Nov 1;116(5):2093-2104
pubmed: 27512019
Front Integr Neurosci. 2019 Jul 17;13:24
pubmed: 31417372
Lancet Neurol. 2019 Jul;18(7):684-696
pubmed: 31097385
BMC Public Health. 2013 Feb 19;13:154
pubmed: 23421987
Neuroimage. 2012 Mar;60(1):340-52
pubmed: 22178809
Brain. 2018 Oct 1;141(10):3065-3080
pubmed: 30239611
Alzheimers Dement (Amst). 2019 Feb 26;11:191-204
pubmed: 30859119
Ann Neurol. 2016 Oct;80(4):581-92
pubmed: 27518166
Front Psychiatry. 2020 May 04;11:342
pubmed: 32425831

Auteurs

Maria Clara Zanon Zotin (MC)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0001-6604-0660

Pinar Yilmaz (P)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0003-2393-3068

Lukas Sveikata (L)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0001-8015-7929

Dorothee Schoemaker (D)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0003-2587-8883

Susanne J van Veluw (SJ)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0002-7957-8643

Mark R Etherton (MR)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0002-4739-2449

Andreas Charidimou (A)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0001-5891-337X

Steven M Greenberg (SM)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0003-1792-8887

Marco Duering (M)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).
ORCID: 0000-0003-2302-3136

Anand Viswanathan (A)

From the J. Philip Kistler Stroke Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, Mass (M.C.Z.Z., P.Y., L.S., D.S., S.J.v.V., M.R.E., A.C., S.M.G., A.V.); Center for Imaging Sciences and Medical Physics, Department of Medical Imaging, Hematology and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, 3900 Ten. Catão Roxo Street, Monte Alegre, Campus Universitário, Ribeirão Preto, SP 14015-010, Brazil (M.C.Z.Z.); Departments of Epidemiology and Radiology and Nuclear Medicine, Erasmus Medical Center, Rotterdam, the Netherlands (P.Y.); Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospital, Faculty of Medicine, University of Geneva, Geneva, Switzerland (L.S.); Institute of Cardiology, Medical Academy, Lithuanian University of Health Sciences, Kaunas, Lithuania (L.S.); and Medical Image Analysis Center (MIAC AG) and Quantitative Biomedical Imaging Group (qbig), Department of Biomedical Engineering, University of Basel, Basel, Switzerland (M.D.).

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Système nerveux › Système nerveux central › Moelle spinale › Substance blanche › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Imagerie par résonance magnétique de diffusion › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Techniques d'investigation › Neuroimagerie › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Techniques d'investigation › Neuroimagerie › Imagerie par tenseur de diffusion › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Troubles mentaux › Troubles neurocognitifs › Troubles de la cognition › Dysfonctionnement cognitif › Peak Width of Skeletonized Mean Diffusivity: A...
questionsmedicales.fr › Maladies cardiovasculaires › Maladies vasculaires › Angiopathies intracrâniennes › Maladies des petits vaisseaux cérébraux › Peak Width of Skeletonized Mean Diffusivity: A...