The leukotriene B
BLT1
BLT1 antagonist
anti-neutrophil cytoplasmic antibody-associated glomerulonephritis
crescentic glomerulonephritis
fibrosis
immune complex-mediated glomerulonephritis
leukotriene B4
neutrophils
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
ISSN: 1530-6860
Titre abrégé: FASEB J
Pays: United States
ID NLM: 8804484
Informations de publication
Date de publication:
02 2023
02 2023
Historique:
revised:
25
12
2022
received:
20
11
2022
accepted:
11
01
2023
entrez:
24
1
2023
pubmed:
25
1
2023
medline:
27
1
2023
Statut:
ppublish
Résumé
Crescent formation is the most important pathological finding that defines the prognosis of nephritis. Although neutrophils are known to play an important role in the progression of crescentic glomerulonephritis, such as anti-neutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis, the key chemoattractant for neutrophils in ANCA-associated glomerulonephritis has not been identified. Here, we demonstrate that a lipid chemoattractant, leukotriene B
Identifiants
pubmed: 36692419
doi: 10.1096/fj.202201936R
doi:
Substances chimiques
Antibodies, Antineutrophil Cytoplasmic
0
Antigen-Antibody Complex
0
Chemotactic Factors
0
Leukotriene B4
1HGW4DR56D
Receptors, Leukotriene B4
0
Ltb4r1 protein, mouse
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e22789Informations de copyright
© 2023 The Authors. The FASEB Journal published by Wiley Periodicals LLC on behalf of Federation of American Societies for Experimental Biology.
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