Association between dietary phosphorus intake and chronic constipation in adults: evidence from the National Health and Nutrition Examination Survey.
Bowel health
Chronic constipation
National Health and Nutrition Examination Survey
Phosphorus
Stool consistency
Stool frequency
Journal
BMC gastroenterology
ISSN: 1471-230X
Titre abrégé: BMC Gastroenterol
Pays: England
ID NLM: 100968547
Informations de publication
Date de publication:
24 Jan 2023
24 Jan 2023
Historique:
received:
25
05
2022
accepted:
20
12
2022
entrez:
24
1
2023
pubmed:
25
1
2023
medline:
27
1
2023
Statut:
epublish
Résumé
Several studies suggest a link between micronutrients and constipation. However, the relationship between constipation and phosphorus has rarely been examined. The main aim of this study was to investigate the association between changes in the prevalence of chronic constipation and dietary phosphorus intake among adult respondents of the National Health and Nutritional Examination Survey (NHANES). Data were extracted from the NHANES database for the years 2005-2010. A total of 13,948 people were included in the analysis. Dietary information was collected using the respondents' 24-h dietary records. We conducted multiple logistic regression analyses to examine the correlation between phosphorus intake and poor bowel movement. The primary and secondary outcomes was constipation defined by stool consistency and stool frequency, respectively. Following multi-variate adjustment in model III, a significant association between chronic constipation and each additional 0.1-g intake of dietary phosphorus (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.95, 1.00; P = 0.034 for stool consistency vs. OR, 0.94; 95% CI, 0.90, 0.99; P = 0.027 for stool frequency) was observed. Following multi-variate adjustment in model III, OR values and 95% CI from the second to fourth quartiles compared to the first quartile (reference group) were 0.92 (0.66, 1.27), 0.73 (0.47, 1.13), and 0.39 (0.20, 0.76), respectively, using the stool frequency definition. This study revealed a negative correlation between phosphorus intake and chronic constipation. This may be due to the fact that dietary phosphorus intake is associated with softer stools and increased stool frequency. Further studies in different settings should be considered to verify these findings.
Sections du résumé
BACKGROUND
BACKGROUND
Several studies suggest a link between micronutrients and constipation. However, the relationship between constipation and phosphorus has rarely been examined. The main aim of this study was to investigate the association between changes in the prevalence of chronic constipation and dietary phosphorus intake among adult respondents of the National Health and Nutritional Examination Survey (NHANES).
METHODS
METHODS
Data were extracted from the NHANES database for the years 2005-2010. A total of 13,948 people were included in the analysis. Dietary information was collected using the respondents' 24-h dietary records. We conducted multiple logistic regression analyses to examine the correlation between phosphorus intake and poor bowel movement. The primary and secondary outcomes was constipation defined by stool consistency and stool frequency, respectively.
RESULTS
RESULTS
Following multi-variate adjustment in model III, a significant association between chronic constipation and each additional 0.1-g intake of dietary phosphorus (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.95, 1.00; P = 0.034 for stool consistency vs. OR, 0.94; 95% CI, 0.90, 0.99; P = 0.027 for stool frequency) was observed. Following multi-variate adjustment in model III, OR values and 95% CI from the second to fourth quartiles compared to the first quartile (reference group) were 0.92 (0.66, 1.27), 0.73 (0.47, 1.13), and 0.39 (0.20, 0.76), respectively, using the stool frequency definition.
CONCLUSIONS
CONCLUSIONS
This study revealed a negative correlation between phosphorus intake and chronic constipation. This may be due to the fact that dietary phosphorus intake is associated with softer stools and increased stool frequency. Further studies in different settings should be considered to verify these findings.
Identifiants
pubmed: 36694113
doi: 10.1186/s12876-022-02629-8
pii: 10.1186/s12876-022-02629-8
pmc: PMC9875444
doi:
Substances chimiques
Phosphorus, Dietary
0
Dietary Fiber
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
24Informations de copyright
© 2023. The Author(s).
Références
Biol Trace Elem Res. 2022 May;200(5):2033-2039
pubmed: 34283364
Am J Gastroenterol. 2019 Jan;114(1):135-142
pubmed: 30410038
Nutrients. 2017 Jan 30;9(2):
pubmed: 28146091
J Am Geriatr Soc. 1983 May;31(5):289-93
pubmed: 6302153
Clin Gastroenterol Hepatol. 2019 Dec;17(13):2696-2703
pubmed: 30954714
J Neurogastroenterol Motil. 2014 Jul 31;20(3):379-87
pubmed: 24935009
Biol Trace Elem Res. 2021 Jul;199(7):2543-2551
pubmed: 32939644
Animals (Basel). 2020 Feb 08;10(2):
pubmed: 32046261
J Neurogastroenterol Motil. 2021 Jan 30;27(1):97-107
pubmed: 33380555
Surg Endosc. 2021 Feb;35(2):900-909
pubmed: 32124060
Am J Gastroenterol. 2013 May;108(5):796-803
pubmed: 23567352
Ann Pharmacother. 2006 Feb;40(2):234-40
pubmed: 16449551
Pediatr Emerg Care. 2011 Dec;27(12):1118-20
pubmed: 22134228
Nat Rev Dis Primers. 2017 Dec 14;3:17095
pubmed: 29239347
Ther Apher Dial. 2005 Feb;9(1):11-5
pubmed: 15828900
Gastroenterology. 2020 Apr;158(5):1262-1273.e3
pubmed: 31917991
Biol Trace Elem Res. 2021 Nov;199(11):4084-4091
pubmed: 33409918
J Nutr. 2010 Mar;140(3):534-41
pubmed: 20089780
Expert Rev Gastroenterol Hepatol. 2020 Jan;14(1):39-46
pubmed: 31893959
Am J Gastroenterol. 2011 Sep;106(9):1582-91; quiz 1581, 1592
pubmed: 21606976
Nutr Res Rev. 2015 Jun;28(1):67-82
pubmed: 26004147
Annu Rev Nutr. 2017 Aug 21;37:321-346
pubmed: 28613982
JAMA. 2016 Apr 26;315(16):1726-34
pubmed: 27115377
Adv Nutr. 2015 Nov 13;6(6):860-2
pubmed: 26567206
Prim Care. 2008 Jun;35(2):215-37, v-vi
pubmed: 18486714
Lancet Gastroenterol Hepatol. 2021 Aug;6(8):638-648
pubmed: 34090581
World J Gastroenterol. 2019 Oct 28;25(40):6129-6144
pubmed: 31686768
Med J Aust. 2018 Jul 16;209(2):86-91
pubmed: 29996755
Scand J Gastroenterol. 1997 Sep;32(9):920-4
pubmed: 9299672
Drugs. 2004;64(15):1697-714
pubmed: 15257632
Biol Trace Elem Res. 2021 Sep;199(9):3205-3212
pubmed: 33095434
Gend Med. 2009 Apr;6(1):259-71
pubmed: 19467522
Int J Colorectal Dis. 2017 Apr;32(4):475-483
pubmed: 27913883
Neurogastroenterol Motil. 2015 Oct;27(10):1389-97
pubmed: 26176421
Aliment Pharmacol Ther. 2007 Jul 1;26(1):9-20
pubmed: 17555417
Nephrol Dial Transplant. 2005 Feb;20(2):424-30
pubmed: 15673691
Bone. 2009 Jul;45 Suppl 1:S8-12
pubmed: 19442621
Gastrointest Endosc. 2009 Jun;69(7):1201-9
pubmed: 19481646
Nutrients. 2021 Sep 06;13(9):
pubmed: 34578996