Determinants and neonatal outcomes of preeclampsia among women living with and without HIV at a tertiary hospital in Zambia: a review of medical records.
HIV-infection
Preeclampsia
Zambia
antiretroviral therapy
determinants
neonatal outcomes
Journal
The Pan African medical journal
ISSN: 1937-8688
Titre abrégé: Pan Afr Med J
Pays: Uganda
ID NLM: 101517926
Informations de publication
Date de publication:
2022
2022
Historique:
received:
21
03
2022
accepted:
17
10
2022
entrez:
26
1
2023
pubmed:
27
1
2023
medline:
28
1
2023
Statut:
epublish
Résumé
pre-eclampsia, a pregnancy-specific condition that occurs after 20 weeks of gestation, is a significant public health problem. In the extant literature, there are still conflicting reports on whether Human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) affect preeclampsia rates. We, therefore, explored the determinants and neonatal outcomes of preeclampsia among pregnant women living with and without HIV. we reviewed delivery registers and neonatal files from the 1 the prevalence of preeclampsia was 7.7% (95% confidence intervals: 6.8 to 8.7). On ART, pregnant women with HIV infection were less likely to develop preeclampsia than those without HIV infection (aOR=0.50; 95% CI: 0.32 to 0.80). However, neonates born to women with preeclampsia were more likely to be admitted to kangaroo mother care than neonates born to normotensive women, regardless of the HIV-exposure status. overall, the prevalence of preeclampsia was 7.7%, but it was less common among HIV-infected pregnant women receiving ART. Neonates born from women with preeclampsia are at increased risk of adverse outcomes, including admission to kangaroo mother care. These findings underscore the need for healthcare workers to direct their efforts on early diagnosis and detection of preeclampsia in pregnant women to prevent poor outcomes.
Identifiants
pubmed: 36699973
doi: 10.11604/pamj.2022.43.110.34390
pii: PAMJ-43-110
pmc: PMC9834805
doi:
Types de publication
Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110Informations de copyright
Copyright: Moses Mukosha et al.
Déclaration de conflit d'intérêts
The authors declare no competing interests.
Références
Am J Obstet Gynecol. 2009 Sep;201(3):315.e1-5
pubmed: 19733286
Clin Hypertens. 2019 Jul 01;25:14
pubmed: 31304042
Cytokine. 2020 Jan;125:154795
pubmed: 31398625
Semin Perinatol. 2009 Jun;33(3):130-7
pubmed: 19464502
Cardiovasc J Afr. 2013 Mar;24(2):24-7
pubmed: 23612949
PLoS One. 2021 Mar 8;16(3):e0247929
pubmed: 33684169
Neurol Res. 2017 Jun;39(6):573-580
pubmed: 28415916
Ultrasound Obstet Gynecol. 2013 May;41(5):491-9
pubmed: 23362106
Placenta. 2014 Feb;35 Suppl:S20-5
pubmed: 24477207
BMC Pregnancy Childbirth. 2018 Feb 21;18(1):56
pubmed: 29466949
PLoS One. 2017 Mar 8;12(3):e0172089
pubmed: 28273105
Int J Gynaecol Obstet. 2002 Apr;77(1):67-75
pubmed: 12094777
Integr Blood Press Control. 2015 Mar 03;8:7-12
pubmed: 25767405
Eur J Obstet Gynecol Reprod Biol. 2004 Dec 1;117(2):240-1
pubmed: 15541864
Eur J Obstet Gynecol Reprod Biol. 2020 May;248:177-186
pubmed: 32283429
BMC Pregnancy Childbirth. 2019 Aug 23;19(1):308
pubmed: 31443707
Int J Gynaecol Obstet. 2016 Sep;134(3):299-303
pubmed: 27365290
Arch Iran Med. 2011 Nov;14(6):412-5
pubmed: 22039846
J Perinat Med. 2011 May;39(3):257-65
pubmed: 21309631
Aust N Z J Obstet Gynaecol. 1995 Nov;35(4):380-5
pubmed: 8717558
Science. 2014 May 23;344(6186):856-61
pubmed: 24855261
Int J Gynaecol Obstet. 2000 Sep;70(3):327-33
pubmed: 10967166
J Matern Fetal Neonatal Med. 2020 Jan;33(2):303-306
pubmed: 29914280
Kaohsiung J Med Sci. 2018 Feb;34(2):109-112
pubmed: 29413226
Biochem Pharmacol. 2020 Dec;182:114247
pubmed: 32986983
Hypertens Pregnancy. 2016 Nov;35(4):529-535
pubmed: 27391770
Eur J Obstet Gynecol Reprod Biol. 2017 Mar;210:126-131
pubmed: 28013100
Mod Rheumatol. 2021 Jul;31(4):843-848
pubmed: 32990121
J Infect. 2014 Jun;68(6):572-80
pubmed: 24462561
AIDS. 2006 Jan 2;20(1):59-66
pubmed: 16327320
Eur J Obstet Gynecol Reprod Biol. 2013 Sep;170(1):1-7
pubmed: 23746796
Pan Afr Med J. 2020 Feb 19;35:49
pubmed: 32537054
Inflamm Res. 2019 Jan;68(1):47-57
pubmed: 30276649
J Family Med Prim Care. 2015 Oct-Dec;4(4):501-6
pubmed: 26985406
Science. 1997 Jul 4;277(5322):112-6
pubmed: 9204894
Obstet Gynecol. 2004 Aug;104(2):238-42
pubmed: 15291993
Acta Obstet Gynecol Scand. 2014 Oct;93(10):973-85
pubmed: 25138651
Lancet. 2002 Oct 12;360(9340):1152-4
pubmed: 12387967
Top Antivir Med. 2020 Jan;27(4):106-111
pubmed: 32224502
Pregnancy Hypertens. 2014 Jan;4(1):91-6
pubmed: 26104261
Pan Afr Med J. 2021 May 25;39:69
pubmed: 34422192
Eur J Obstet Gynecol Reprod Biol. 2003 Nov 10;111(1):3-8
pubmed: 14557003
Science. 2005 Jun 10;308(5728):1592-4
pubmed: 15947178
Hypertens Pregnancy. 2019 May;38(2):89-95
pubmed: 30836796
BJOG. 2007 Feb;114(2):148-55
pubmed: 17305888
J Geriatr Cardiol. 2011 Dec;8(4):230-42
pubmed: 22783310
BMC Cardiovasc Disord. 2015 Oct 02;15:111
pubmed: 26431848
J Obstet Gynaecol Can. 2012 Feb;34(2):136-141
pubmed: 22340062
Eur J Obstet Gynecol Reprod Biol. 2021 Aug;263:15-19
pubmed: 34129962
Dakar Med. 2007;52(2):148-52
pubmed: 19102110
Curr Hypertens Rep. 2017 Aug;19(8):61
pubmed: 28689331
BMC Immunol. 2019 Aug 28;20(1):31
pubmed: 31455209
J Reprod Immunol. 2007 Dec;76(1-2):75-7
pubmed: 17568688
Int J Gynaecol Obstet. 2016 Apr;133(1):17-21
pubmed: 26797203
J Acquir Immune Defic Syndr. 2013 Apr 15;62(5):517-24
pubmed: 23344545
Lancet. 2016 Jan 30;387(10017):462-74
pubmed: 26584737
Biomed Res Int. 2014;2014:406960
pubmed: 25136585
Infection. 2017 Oct;45(5):589-600
pubmed: 28577241