Determination of phthalic acid esters (PAEs) along with probabilistic health risk assessment in fruit juice samples in Tehran, Iran.


Journal

Environmental science and pollution research international
ISSN: 1614-7499
Titre abrégé: Environ Sci Pollut Res Int
Pays: Germany
ID NLM: 9441769

Informations de publication

Date de publication:
Mar 2023
Historique:
received: 26 08 2022
accepted: 10 01 2023
medline: 7 4 2023
pubmed: 27 1 2023
entrez: 26 1 2023
Statut: ppublish

Résumé

In the present study, magnetic solid phase extraction (MSPE) method and gas chromatography-mass spectrometry (GC/MS) technique were used to measure 6 PAE in fruit juice samples. The mean of total phthalic acid esters (ƩPAEs) in all samples was 3.55 ± 0.66 µg/L. The mean concentration of DEHP (bis(2-ethylhexyl) phthalate) in samples was 0.82 ± 0.31 µg/L, which was lower than the mentioned United States Environmental Protection Agency (USEPA) standard level in drinking water (6 μg/L for DEHP). The pineapple juice samples (4.44 ± 0.57 µg/L) and mango juice samples (2.77 ± 0. 1 µg/L) had maximum and minimum mean levels of ƩPAEs, respectively. Also, results showed that brand B (3.76 ± 0.87 µg/L) and samples in the time of expiration date (3.64 ± 0.72 µg/L) had the highest PAE levels. The rank order Chronic Daily Intake (95%) values for adults were DEHP ([Formula: see text]) > butylbenzyl phthalates (BBP) ([Formula: see text]) > diethyl phthalate (DEP) ([Formula: see text]) and for children were DEHP ([Formula: see text]) > BBP (9.07E-04) > DEP ([Formula: see text]), which were below the tolerable daily intake (TDI) value. The noncancer risk of PAEs based on the target hazard quotient (THQ) was acceptable (< 1). The results exhibited that the Incremental Lifetime Cancer Risk (ILCR) was below the permissible limit (< [Formula: see text]). Therefore, the risk of carcinogenicity and noncarcinogenicity of PAEs in juices does not have adverse effects on human health.

Identifiants

pubmed: 36701052
doi: 10.1007/s11356-023-25313-0
pii: 10.1007/s11356-023-25313-0
doi:

Substances chimiques

phthalic acid 6O7F7IX66E
Diethylhexyl Phthalate C42K0PH13C
Phthalic Acids 0
Esters 0
Dibutyl Phthalate 2286E5R2KE

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

44833-44844

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Références

Ahmadloo M, Shariatifar N, Mahmoudi R, Qajarbeygi P, Moazzen M, Akbarzadeh A, Nazmara S, Dobaradaran S (2019) Assessment of polychlorinated biphenyls concentration in egg using GC-MS method. J Maz Univ Med Sci 28:69–81
Al-Saleh I, Elkhatib R (2014) Analysis of phthalates residues in apple juices produced in Saudi Arabia. J Food Meas Charact 8:373–380
doi: 10.1007/s11694-014-9202-7
Amiridou D, Voutsa D (2011) Alkylphenols and phthalates in bottled waters. J Hazard Mater 185:281–286
doi: 10.1016/j.jhazmat.2010.09.031
Arabameri M, Mohammadi Moghadam M, Monjazeb Marvdashti L, Mehdinia SM, Abdolshahi A, Dezianian A (2020) Pesticide residues in pistachio nut: a human risk assessment study. Int J Environ Anal Chem 102(16):3947–3960. https://doi.org/10.1080/03067319.2020.1777289
doi: 10.1080/03067319.2020.1777289
Cao X-L (2008) Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry. J Chromatogr A 1178:231–238
doi: 10.1016/j.chroma.2007.11.095
Cao Y, Liu J, Liu Y, Wang J, Hao X (2016) An integrated exposure assessment of phthalates for the general population in China based on both exposure scenario and biomonitoring estimation approaches. Regul Toxicol Pharmacol 74:34–41
doi: 10.1016/j.yrtph.2015.11.019
da Silva CR, Sainara Maia Fernandes T, de Sousa AE, Tomé Oliveira J, Carvalho Guedes JA, Julião Zocolo G, Wagner de Sousa F, do Nascimento RF (2021) Potential risk of BPA and phthalates in commercial water bottles: a minireview. J Water Health 19:411–435
doi: 10.2166/wh.2021.202
Dobaradaran S, Akhbarizadeh R, Mohammadi MJ, Izadi A, Keshtkar M, Tangestani M, Moazzen M, Shariatifar N, Mahmoodi M (2020) Determination of phthalates in bottled milk by a modified nano adsorbent: presence, effects of fat and storage time, and implications for human health. Microchem J 159:105516
doi: 10.1016/j.microc.2020.105516
EFSA Panel on Food Contact Materials E, Aids P, Silano V, Barat Baviera JM, Bolognesi C, Chesson A, Cocconcelli PS, Crebelli R, Gott DM, Grob K, Lampi E (2019) Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis (2-ethylhexyl) phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials. EFSA J 17:e05838
Eghbaljoo-Gharehgheshlaghi H, Shariatifar N, Arab A, Alizadeh-Sani M, sani IK, Asdagh A, Rostami M, Alikord M, Arabameri M (2020) The concentration and probabilistic health risk assessment of trace metals in three type of sesame seeds using ICP- OES in Iran. Int J Environ Anal Chem 102(17):5936–5950. https://doi.org/10.1080/03067319.2020.1804896
EPA (2009) Agency EUSEP. Integrated risk information system. Butyl benzyl phthalate (BBP), CASRN 85–68–7; di(2-ethylhexyl) phthalate (DEHP), CASRN 117–81–7; diethyl phthalate, CASRN 84–66–2; dibutyl phthalate (DBP), CASRN 84–74–2. Accessible at. https://cfpub.epa.gov/ncea/iris_drafts/simple_list.cfm . 2009
EPA (2011) Exposure Factors Handbook. 2011 ed., Final Report. Environmental Protection Agency, Washington, DC EPA/600/R-09/052F. https://www.epa.gov/
Farhoodi M, Emam-Djomeh Z, Ehsani MR, Oromiehie A (2008) Effect of environmental conditions on the migration of di (2-ethylhexyl) phthalate from PET bottles into yogurt drinks: influence of time, temperature, and food simulant. Arabian J Sci Eng 33:279–287
Kalantari N GM (2015) National Report of "The comprehensive study on household food consumption patterns and nutritional status of I.R.Iran. Nutrition Research Group, National Nutrition and Food Technology Research Institute, Shaheed Beheshti University of Medical Sciences, Ministry of Health
Karami H, Shariatifar N, Nazmara S, Moazzen M, Mahmoodi B, Khaneghah AM (2021) The concentration and probabilistic health risk of potentially toxic elements (PTEs) in edible mushrooms (wild and cultivated) samples collected from different cities of Iran. Biol Trace Elem Res 199:389–400
doi: 10.1007/s12011-020-02130-x
Karimi F, Shariatifar N, Rezaei M, Alikord M, Arabameri M (2021) Quantitative measurement of toxic metals and assessment of health risk in agricultural products food from Markazi Province of Iran. Int J Food Contam 8:1–7
doi: 10.1186/s40550-021-00083-0
Khalili F, Shariatifar N, Dehghani MH, Yaghmaeian K, Nodehi RN, Yaseri M, Arabameri M (2022) The analysis and probabilistic health risk assessment of polycyclic aromatic hydrocarbons in cereal products. Environ Sci Pollut Res 29(21):31099–31109. https://doi.org/10.1007/s11356-021-17337-1
doi: 10.1007/s11356-021-17337-1
Kiani A, Ahmadloo M, Shariatifar N, Moazzen M, Baghani AN, Khaniki GJ, Taghinezhad A, Kouhpayeh A, Khaneghah AM, Ghajarbeygi P (2018) Method development for determination of migrated phthalate acid esters from polyethylene terephthalate (PET) packaging into traditional Iranian drinking beverage (Doogh) samples: a novel approach of MSPE-GC/MS technique. Environ Sci Pollut Res 25:12728–12738
doi: 10.1007/s11356-018-1471-y
Kiani A, Ahmadloo M, Moazzen M, Shariatifar N, Shahsavari S, Arabameri M, Hasani MM, Azari A, Abdel-Wahhab MA (2021) Monitoring of polycyclic aromatic hydrocarbons and probabilistic health risk assessment in yogurt and butter in Iran. Food Sci Nutr 9:2114–2128
doi: 10.1002/fsn3.2180
Kouhpayeh A, Moazzen M, Jahed Khaniki GR, Dobaradaran S, Shariatifar N, Ahmadloo M, Azari A, Nazmara S, Kiani A, Salari M (2017) Extraction and determination of phthalate esters (PAEs) in Doogh. J Maz Univ Med Sci 26:257–267
Li X, Zeng Z, Chen Y, Xu Y (2004) Determination of phthalate acid esters plasticizers in plastic by ultrasonic solvent extraction combined with solid-phase microextraction using calix [4] arene fiber. Talanta 63:1013–1019
doi: 10.1016/j.talanta.2004.01.006
Mehraie A, Shariatifar N, Arabameri M, Moazzen M, Mortazavian AM, Sheikh F, Sohrabvandi S (2022) Determination of phthalate acid esters (PAEs) in bottled water distributed in tehran: a health risk assessment study. Int J Environ Anal Chem 1–15. https://doi.org/10.1080/03067319.2022.2062239
Moazzen M, Ahmadkhaniha R, Gorji MEh, Yunesian M, Rastkari N (2013) Magnetic solid-phase extraction based on magnetic multi-walled carbon nanotubes for the determination of polycyclic aromatic hydrocarbons in grilled meat samples. Talanta 115:957–965
doi: 10.1016/j.talanta.2013.07.005
Moazzen M, Rastkari N, Alimohammadi M, Shariatifar N, Ahmadkhaniha R, Nazmara S (2014) Assessment of phthalate esters in a variety of carbonated beverages bottled in PET. J Environ Health Sci 2:7–18
Moazzen M, Mahvi AH, Shariatifar N, Jahed Khaniki G, Nazmara S, Alimohammadi M, Ahmadkhaniha R, Rastkari N, Ahmadloo M, Akbarzadeh A, Dobaradaran S, Norouzian Baghani A (2018) Determination of phthalate acid esters (PAEs) in carbonated soft drinks with MSPE/GC–MS method. Toxin Rev 37:319–326
doi: 10.1080/15569543.2017.1378234
Moazzen M, Khaneghah AM, Shariatifar N, Ahmadloo M, Eş I, Baghani AN, Yousefinejad S, Alimohammadi M, Azari A, Dobaradaran S (2019) Multi-walled carbon nanotubes modified with iron oxide and silver nanoparticles (MWCNT-Fe3O4/Ag) as a novel adsorbent for determining PAEs in carbonated soft drinks using magnetic SPE-GC/MS method. Arab J Chem 12:476–488
doi: 10.1016/j.arabjc.2018.03.003
Moazzen M, Shariatifar N, Arabameri M, Hosseini H, Ahmadloo M (2022) Measurement of polycyclic aromatic hydrocarbons in baby food samples in Tehran Iran with magnetic-aolid-phase-extraction and gas-chromatography/mass-spectrometry method: a health risk assessment. Front Nutr 9833158. https://doi.org/10.3389/fnut.2022.833158
Rastkari N, Jeddi MZ, Yunesian M, Ahmadkhaniha R (2018) Effect of sunlight exposure on phthalates migration from plastic containers to packaged juices. J Environ Health Sci Eng 16:27–33
doi: 10.1007/s40201-018-0292-8
Rezaei M, Khorasgani ZN, Nakisa A, Imani N, Rezaee S, Khodayar MJ, Kalantari H (2015) Determination of polychlorinated dibenzo dioxin levels in fresh milk from the dairy factories of Southwest Iran. J Environ Anal Toxicol 5(2161–0525):1000
Rezaei H, Moazzen M, Shariatifar N, Khaniki GJ, Dehghani MH, Arabameri M, Alikord M (2021) Measurement of phthalate acid esters in non-alcoholic malt beverages by MSPE-GC/MS method in Tehran city: chemometrics. Environ Sci Pollut Res 28(37):51897–51907. https://doi.org/10.1007/s11356-021-14290-x
doi: 10.1007/s11356-021-14290-x
Roudbari A, Nazari RR, Shariatifar N, Moazzen M, Abdolshahi A, Mirzamohammadi S, Madani-Tonekaboni M, Delvarianzadeh M, Arabameri M (2021) Concentration and health risk assessment of polycyclic aromatic hydrocarbons in commercial tea and coffee samples marketed in Iran. Environ Sci Pollut Res 28:4827–4839
doi: 10.1007/s11356-020-10794-0
Samiee S, Fakhri Y, Sadighara P, Arabameri M, Rezaei M, Nabizadeh R, Shariatifar N, Khaneghah AM (2020) The concentration of polycyclic aromatic hydrocarbons (PAHs) in the processed meat samples collected from Iran’s market: a probabilistic health risk assessment study. Environ Sci Pollut Res 27(17):21126–21139. https://doi.org/10.1007/s11356-020-08413-z
doi: 10.1007/s11356-020-08413-z
Shahsavari S, Shariatifar N, Arabameri M, Mahmoudi R, Moazzen M, Ghajarbeygi P (2022) Analysis of polychlorinated biphenyls in cream and ice cream using modified QuEChERS extraction and GC-QqQ-MS/MS method: a risk assessment study. Int J Dairy Technol 75:448–459
doi: 10.1111/1471-0307.12849
Shariatifar N, Dadgar M, Fakhri Y, Shahsavari S, Moazzen M, Ahmadloo M, Kiani A, Aeenehvand S, Nazmara S, Khanegah AM (2020) Levels of polycyclic aromatic hydrocarbons in milk and milk powder samples and their likely risk assessment in Iranian population. J Food Compos Anal 85:103331
doi: 10.1016/j.jfca.2019.103331
Shariatifar N, Moazzen M, Arabameri M, Moazzen M, Khaniki GJ, Sadighara P (2021b) Measurement of polycyclic aromatic hydrocarbons (PAHs) in edible mushrooms (raw, grilled and fried) using MSPE-GC/MS method: a risk assessment study. Appl Biol Chem 64:1–11
doi: 10.1186/s13765-021-00634-1
Shariatifar N, Seilani F, Jannat B, Nazmara S, Arabameri M (2022) The concentration and health risk assessment of trace elements in commercial soft drinks from Iran marketed. Int J Environ Anal Chem 102(16):4388–4402. https://doi.org/10.1080/03067319.2020.1784412
doi: 10.1080/03067319.2020.1784412
Sharman M, Read WA, Castle L, Gilbert J (1994) Levels of di-(2-ethylhexyl) phthalate and total phthalate esters in milk, cream, butter and cheese. Food Addit Contam 11:375–385
doi: 10.1080/02652039409374236
Tang Z, Kang T, Kang X (2019) Determination of five phthalate esters and bisphenol A in fruit juice by packed-nanofiber solid phase extraction coupled with gas chromatography. J Food Eng 8:50–54
doi: 10.32732/jfet.2019.8.1.50
Yaminifar S, Aeenehvand S, Ghelichkhani G, Ahmadloo M, Arabameri M, Moazzen M, Shariatifar N (2021) The measurement and health risk assessment of polychlorinated biphenyls in butter samples using the QuEChERS/GC-MS method. Int J Dairy Technol 74:737–746
doi: 10.1111/1471-0307.12805
Yin S, Yang Y, Yang D, Li Y, Jiang Y, Wu L, Sun C (2019) Determination of 11 phthalate esters in beverages by magnetic solid-phase extraction combined with high-performance liquid chromatography. J AOAC Int 102:1624–1631
doi: 10.5740/jaoacint.18-0316
Zare Jeddi M, Ahmadkhaniha R, Yunesian M, Rastkari N (2014) Magnetic solid-phase extraction based on modified magnetic nanoparticles for the determination of phthalate diesters in water samples. J Chromatogr Sci 53:385–391
doi: 10.1093/chromsci/bmu058

Auteurs

Pegah Kargarghomsheh (P)

Department of Food Science, University of Massachusetts, Amherst, MA, 01003, USA.

Mahsa Naghashan (M)

Department of Food Science and Technology, Ferdowsi University of Mashhad, Mashhad, Iran.

Soraya Farhadiyan (S)

Chemistry Department, Faculty of Science, Payame Noor University, Ahvaz, Iran.

Majid Arabameri (M)

Food and Drug Laboratory Research Center, Food and Drug Organization, Ministry of Health and Medical Education, Tehran, Iran.

Fahimeh Tooryan (F)

Department of Food Hygiene, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran. f.tooryan@ausmt.ac.ir.
Preventive Veterinary Medicine Graduate Group, School of Veterinary Medicine, University of California, Davis, CA, USA. f.tooryan@ausmt.ac.ir.

Nabi Shariatifar (N)

Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH