Three doses of BNT162b2 COVID-19 mRNA vaccine establish long-lasting CD8
CD8+ T cell
Hematological cancer
SARS – CoV – 2
T cell memory
T-cell immunity
mRNA vaccine against SARS-CoV-2
Journal
Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960
Informations de publication
Date de publication:
2022
2022
Historique:
received:
02
09
2022
accepted:
20
12
2022
entrez:
27
1
2023
pubmed:
28
1
2023
medline:
31
1
2023
Statut:
epublish
Résumé
Patients with hematological malignancies are prioritized for COVID-19 vaccine due to their high risk for severe SARS-CoV-2 infection-related disease and mortality. To understand T cell immunity, its long-term persistence, and its correlation with antibody response, we evaluated the BNT162b2 COVID-19 mRNA vaccine-specific immune response in chronic lymphocytic leukemia (CLL) and myeloid dysplastic syndrome (MDS) patients. Longitudinal analysis of CD8
Identifiants
pubmed: 36703960
doi: 10.3389/fimmu.2022.1035344
pmc: PMC9873231
doi:
Substances chimiques
BNT162 Vaccine
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1035344Informations de copyright
Copyright © 2023 Hernandez, Hersby, Munk, Tamhane, Trubach, Tagliamonte, Buonaguro, Gang, Hadrup and Saini.
Déclaration de conflit d'intérêts
SH is the cofounder of PokeAcell and is the co-inventor of the patents WO2015185067 and WO2015188839 for the barcoded MHC technology which is licensed to Immudex and co-inventor of the licensed patent for Combination encoding of MHC multimers EP2088/009356, licensee: Sanquin, NL. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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