Effectiveness of iodine-impregnated incise drapes for preventing surgical site infection in patients with clean or clean contaminated wounds: A systematic literature review and cost-consequence analysis.
Cost-consequence analysis
Infection control
Iodine-impregnated incise drapes
Surgical site infection
Systematic review
Journal
Journal of perioperative practice
ISSN: 2515-7949
Titre abrégé: J Perioper Pract
Pays: England
ID NLM: 101271023
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
medline:
4
12
2023
pubmed:
28
1
2023
entrez:
27
1
2023
Statut:
ppublish
Résumé
Surgical site infection is a serious complication associated with significant morbidity, mortality and health care expenditure. To determine the clinical effectiveness and economic impact of using iodine-impregnated incise drapes for preventing surgical site infection. MEDLINE, Embase, Cochrane Library and CINAHL databases were systematically searched. Critical appraisal and synthesis of clinical evidence informed a decision analytical cost-consequence model. Nine studies were included in the systematic literature review. Evidence from cardiac surgery patients was considered appropriate to inform the cost analysis. The economic model evaluation estimated cost savings of £549 per patient with the iodophor-impregnated drape in the deterministic analysis and a mean cost saving per patient of £554,172 per 1000 in the probabilistic analysis. Using iodine-impregnated drapes in cardiac surgery patients may effectively reduce infections and provide cost-savings, but further research is required.
Sections du résumé
BACKGROUND
UNASSIGNED
Surgical site infection is a serious complication associated with significant morbidity, mortality and health care expenditure.
AIMS
UNASSIGNED
To determine the clinical effectiveness and economic impact of using iodine-impregnated incise drapes for preventing surgical site infection.
METHODS
UNASSIGNED
MEDLINE, Embase, Cochrane Library and CINAHL databases were systematically searched. Critical appraisal and synthesis of clinical evidence informed a decision analytical cost-consequence model.
FINDINGS
UNASSIGNED
Nine studies were included in the systematic literature review. Evidence from cardiac surgery patients was considered appropriate to inform the cost analysis. The economic model evaluation estimated cost savings of £549 per patient with the iodophor-impregnated drape in the deterministic analysis and a mean cost saving per patient of £554,172 per 1000 in the probabilistic analysis.
CONCLUSION
UNASSIGNED
Using iodine-impregnated drapes in cardiac surgery patients may effectively reduce infections and provide cost-savings, but further research is required.
Identifiants
pubmed: 36705002
doi: 10.1177/17504589221139603
pmc: PMC10693728
doi:
Substances chimiques
Iodine
9679TC07X4
Types de publication
Systematic Review
Journal Article
Review
Langues
eng
Pagination
368-379Références
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