Analysis of Multiple Causes of Death: A Review of Methods and Practices.
Journal
Epidemiology (Cambridge, Mass.)
ISSN: 1531-5487
Titre abrégé: Epidemiology
Pays: United States
ID NLM: 9009644
Informations de publication
Date de publication:
01 05 2023
01 05 2023
Historique:
medline:
6
4
2023
pubmed:
1
2
2023
entrez:
31
1
2023
Statut:
ppublish
Résumé
Research and reporting of mortality indicators typically focus on a single underlying cause of death selected from multiple causes recorded on a death certificate. The need to incorporate the multiple causes in mortality statistics-reflecting increasing multimorbidity and complex causation patterns-is recognized internationally. This review aims to identify and appraise relevant analytical methods and practices related to multiple causes. We searched Medline, PubMed, Scopus, and Web of Science from their incept ion to December 2020 without language restrictions, supplemented by consultation with international experts. Eligible articles analyzed multiple causes of death from death certificates. The process identified 4,080 items of which we reviewed 434 full-text articles. Most articles we reviewed (76%, n = 332) were published since 2001. The majority of articles examined mortality by "any- mention" of the cause of death (87%, n = 377) and assessed pairwise combinations of causes (57%, n = 245). Since 2001, applications of methods emerged to group deaths based on common cause patterns using, for example, cluster analysis (2%, n = 9), and application of multiple-cause weights to re-evaluate mortality burden (1%, n = 5). We describe multiple-cause methods applied to specific research objectives for approaches emerging recently. This review confirms rapidly increasing international interest in the analysis of multiple causes of death and provides the most comprehensive overview, to our knowledge, of methods and practices to date. Available multiple-cause methods are diverse but suit a range of research objectives. With greater availability of data and technology, these could be further developed and applied across a range of settings.
Sections du résumé
BACKGROUND
Research and reporting of mortality indicators typically focus on a single underlying cause of death selected from multiple causes recorded on a death certificate. The need to incorporate the multiple causes in mortality statistics-reflecting increasing multimorbidity and complex causation patterns-is recognized internationally. This review aims to identify and appraise relevant analytical methods and practices related to multiple causes.
METHODS
We searched Medline, PubMed, Scopus, and Web of Science from their incept ion to December 2020 without language restrictions, supplemented by consultation with international experts. Eligible articles analyzed multiple causes of death from death certificates. The process identified 4,080 items of which we reviewed 434 full-text articles.
RESULTS
Most articles we reviewed (76%, n = 332) were published since 2001. The majority of articles examined mortality by "any- mention" of the cause of death (87%, n = 377) and assessed pairwise combinations of causes (57%, n = 245). Since 2001, applications of methods emerged to group deaths based on common cause patterns using, for example, cluster analysis (2%, n = 9), and application of multiple-cause weights to re-evaluate mortality burden (1%, n = 5). We describe multiple-cause methods applied to specific research objectives for approaches emerging recently.
CONCLUSION
This review confirms rapidly increasing international interest in the analysis of multiple causes of death and provides the most comprehensive overview, to our knowledge, of methods and practices to date. Available multiple-cause methods are diverse but suit a range of research objectives. With greater availability of data and technology, these could be further developed and applied across a range of settings.
Identifiants
pubmed: 36719759
doi: 10.1097/EDE.0000000000001597
pii: 00001648-202305000-00005
pmc: PMC10069753
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
333-344Informations de copyright
Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest.
Références
Piffaretti C, Moreno-Betancur M, Lamarche-Vadel A, Rey G. Quantifying cause-related mortality by weighting multiple causes of death. Bull World Health Organ. 2016;94:870–879.
Rao C. Medical certification of cause of death for COVID-19. Bull World Health Organ. 2020;98:298–298A.
Desesquelles A, Demuru E, Salvatore MA, et al. Mortality from Alzheimer’s disease, Parkinson’s disease, and dementias in France and Italy: a comparison using the multiple cause-of-death approach. J Aging Health. 2014;26:283–315.
Morrell S, Taylor R, Nand D, Rao C. Changes in proportional mortality from diabetes and circulatory disease in Mauritius and Fiji: possible effects of coding and certification. BMC Public Health. 2019;19:481.
Nguyen-Nielsen M, Moller H, Tjonneland A, Borre M. Causes of death in men with prostate cancer: results from the Danish Prostate Cancer Registry (DAPROCAdata). Cancer Epidemiol. 2019;59:249–257.
Pinault L, Brauer M, Crouse DL, et al. Diabetes status and susceptibility to the effects of PM2.5 exposure on cardiovascular mortality in a national Canadian cohort. Epidemiology. 2018;29:784–794.
D’Amico M, Agozzino E, Biagino A, Simonetti A, Marinelli P. Ill-defined and multiple causes on death certificates--a study of misclassification in mortality statistics. Eur J Epidemiol. 1999;15:141–148.
Mannino DM, Brown C, Giovino GA. Obstructive lung disease deaths in the United States from 1979 through 1993. An analysis using multiple-cause mortality data. Am J Respir Crit Care Med. 1997;156(3 Pt 1):8148148–8148818.
World Health Organization. International statistical classification of diseases and related health problems. - 10th revision, Fifth edition. Vol. 2. World Health Organization; 2016.
Israel RA, Rosenberg HM, Curtin LR. Analytical potential for multiple cause-of-death data. [Review] [59 refs]. Am J Epidemiol. 1986;124:16116179–16116179.
Stallard E. Underlying and multiple case mortality advanced ages: United States 1980-1998. N Amer Actuarial J. 2002;6:64–87.
Chamblee RF, Evans MC. New dimensions in cause of death statistics. Am J Public Health. 1982;72:1265–1270.
Desesquelles A, Salvatore MA, Frova L, et al. Revisiting the mortality of France and Italy with the multiple-cause-of-death approach. Demogr Res. 2010;23:771–805.
Bah S. Using multiple-cause mortality data to resolve conflicting information on trends in maternal mortality in South Africa. S Afr Med J. 2006;96:308.
Bah S, Rahman MM. On measures of association for multiple cause mortality: do we need more measures? Canadian Stud Popul. 2011;38:93–104.
Puffer RR. New approaches for epidemiologic studies of mortality statistics. Bull Pan Am Health Organ. 1989;23:365–383.
Bah S. Measures of multiple-cause mortality: a synthesis and a notational framework. Genus. 2009;65:29–43.
Paik JM, Golabi P, Biswas R, Alqahtani S, Venkatesan C, Younossi ZM. Nonalcoholic fatty liver disease and alcoholic liver disease are major drivers of liver mortality in the United States. Hepatol Commun. 2020;4:890–903.
Rodriguez F, Blum MR, Falasinnu T, et al. Diabetes-attributable mortality in the United States from 2003 to 2016 using a multiple-cause-of-death approach. Diabetes Res Clin Pract. 2019;148:169–178.
Simmons R, Ireland G, Ijaz S, Ramsay M, Mandal S. Causes of death among persons diagnosed with hepatitis C infection in the pre- and post-DAA era in England: a record linkage study. J Viral Hepat. 2019;26:873–880.
Avouac J, Amrouche F, Meune C, Rey G, Kahan A, Allanore Y. Mortality profile of patients with rheumatoid arthritis in France and its change in 10 years. Semin Arthritis Rheum. 2017;46:537–543.
Park CB, Yokoyama E, Tokuyama GH. Medical conditions at death among the caucasian and Japanese elderly in Hawaii - analysis of multiple causes of death, 1976-78. J Clin Epidemiol. 1991;44:519–530.
Garcia Benavides F, Godoy C, Perez S, Bolumar F. Codificación Múltiple de las Causas de Muerte: de Morir «Por» a Morir «Con». Gac Sanit. 1992;6:53–57.
Wall MM, Huang J, Oswald J, McCullen D. Factors associated with reporting multiple causes of death. BMC Med Res Methodol. 2005;5:4.
Zargar AH, Wani AI, Masoodi SR, et al. Causes of mortality in diabetes mellitus: data from a tertiary teaching hospital in India. Postgrad Med J. 2009;85:227–232.
Nembhard WN, Pathak EB, Schocken DD. Racial/ethnic disparities in mortality related to congenital heart defects among children and adults in the United States. Ethn Dis. 2008;18:442–449.
Thomas SL, Griffiths C, Smeeth L, Rooney C, Hall AJ. Burden of mortality associated with autoimmune diseases among females in the United Kingdom. Am J Public Health. 2010;100:2279–2287.
Goldacre MJ, Duncan M, Griffith M, Turner MR. Trends in death certification for multiple sclerosis, motor neuron disease, Parkinson’s disease and epilepsy in English populations 1979-2006. J Neurol. 2010;257:706–715.
Goldacre MJ, Duncan ME, Griffith M, Cook-Mozaffari P. Psychiatric disorders certified on death certificates in an English population. Soc Psychiatry Psychiatr Epidemiol. 2006;41:409–414.
Jansson B, Johansson LA, Rosen M, Svanstrom L. National adaptations of the ICD rules for classification--a problem in the evaluation of cause-of-death trends. J Clin Epidemiol. 1997;50:367–375.
Lu TH, Hsiao A, Chang PC, et al. Counting injury deaths: a comparison of two definitions and two countries. Inj Prev. 2013;21(e1):e127–e132.
Goldberger N, Applbaum Y, Meron J, Haklai Z. High Israeli mortality rates from diabetes and renal failure - Can international comparison of multiple causes of death reflect differences in choice of underlying cause? Isr J Health Policy Res. 2015;4:31.
Désesquelles A, Gamboni A, Demuru E, et al. We only die once... but from how many causes? Popul Soc. 2016;534:1–4.
Désesquelles A, Demuru E, Egidi V, Grova L, Meslé F, Pappagallo M, Salvatore MA. Cause-specific mortality analysis: is the underlying cause of death sufficient? Revue Quetel. 2014;2:119–135.
Cummings PL, Kuo T, Javanbakht M, Sorvillo F. Trends, productivity losses, and associated medical conditions among toxoplasmosis deaths in the United States, 2000-2010. Am J Trop Med Hyg. 2014;91:959–964.
Manton KG, Stallard E, Poss SS. Estimates of U.S. multiple cause life tables. Demography. 1980;17:85–102.
Manton KG, Stallard E. Temporal trends in U. S. multiple cause of death mortality data: 1968 to 1977. Demography. 1982;19:527–547.
Manton KG, Baum HM. CVD mortality, 1968-1978: observations and implications. Stroke. 1984;15:451–457.
Manton KG. Cause specific mortality patterns among the oldest old: multiple cause of death trends 1968 to 1980. J Gerontol. 1986;41:282–289.
Moussa MA, El Sayed AM, Sugathan TN, Khogali MM, Verma D. Analysis of underlying and multiple-cause mortality data. Genus. 1992;48:89–105.
Makela P. Alcohol-related mortality by age and sex and its impact on life expectancy - Estimates based on the Finnish death register. Eur J Public Health. 1998;8:43–51.
Li SQ, Cunningham J, Cass A. Renal-related deaths in Australia 1997-1999. Intern Med J. 2004;34:259–265.
Yoon YH, Stinson FS, Yi HY, Dufour MC. Accidental alcohol poisoning mortality in the United States, 1996-1998. Alcohol Res Health. 2003;27:110–118.
Mannino DM, Ford E, Giovino GA, Thun M. Lung cancer deaths in the United States from 1979 to 1992: an analysis using multiple-cause mortality data. Int J Epidemiol. 1998;27:159–166.
Chamblee RF, Evans MC, Patten DG, Pearce JS. Injuries causing death: their nature, external causes, and associated diseases. J Safety Res. 1983;14:21–35.
McCoy L, Redelings M, Sorvillo F, Simon P. A multiple cause-of-death analysis of asthma mortality in the United States, 1990-2001. J Asthma. 2005;42:757–763.
Redelings MD, Wise M, Sorvillo F. Using multiple cause-of-death data to investigate associations and causality between conditions listed on the death certificate. Am J Epidemiol. 2007;166:104–108.
Wickramasekaran RN, Sorvillo F, Kuo T. Legionnaires’ disease and associated comorbid conditions as causes of death in the U.S., 2000-2010. Public Health Rep. 2015;130:222–229.
Wilkins K, Parsons GF, Gentleman JF, Forbes WF. Deaths due to dementia: an analysis of multiple-cause-of-death data. Chronic Dis Can. 1999;20:26–35.
Arif N, Yousfi S, Vinnard C. Deaths from necrotizing fasciitis in the United States, 2003-2013. Epidemiol Infect. 2016;144:1338–1344.
Barragan NC, Moschetti K, Smith LV, Sorvillo F, Kuo T. Differential declines in syphilis-related mortality in the United States, 2000-2014. Am J Infect Control. 2017;45:417–420.
Croker C, Reporter R, Redelings M, Mascola L. Strongyloidiasis-related deaths in the United States, 1991-2006. Am J Trop Med Hyg. 2010;83:422–426.
Cummings PL, Sorvillo F, Kuo T. Salmonellosis-related mortality in the United States, 1990-2006. Foodborne Pathog Dis. 2010;7:1393–1399.
Barragan NC, Sorvillo F, Kuo T. Cryptococcosis-related deaths and associated medical conditions in the United States, 2000-2010. Mycoses. 2014;57:741–746.
Rockett IR, Lian Y, Stack S, Ducatman AM, Wang S. Discrepant comorbidity between minority and white suicides: a national multiple cause-of-death analysis. BMC Psychiatry. 2009;9:10.
Rockett IR, Wang S, Lian Y, Stack S. Suicide-associated comorbidity among US males and females: a multiple cause-of-death analysis. Inj Prev. 2007;13:311–315.
Vinnard C, Longworth S, Mezochow A, Patrawalla A, Kreiswirth BN, Hamilton K. Deaths related to nontuberculous mycobacterial infections in the United States, 1999-2014. Ann Am Thorac Soc. 2016;13:1951–1955.
Whiteside YO, Selik R, An Q, et al. Comparison of rates of death having any death-certificate mention of heart, kidney, or liver disease among persons diagnosed with HIV infection with those in the general US population, 2009-2011. Open AIDS J. 2015;9:14–22.
Fedeli U, Avossa F, Guzzinati S, Bovo E, Saugo M. Trends in mortality from chronic liver disease. Ann Epidemiol. 2014;24:522–526.
Desesquelles AF, Salvatore MA, Pappagallo M, et al. Analysing multiple causes of death: which methods for which data? An application to the cancer-related mortality in France and Italy. Eur J Popul Revue Eur De Demographie. 2012;28:467–498.
Adair T, Lopez AD. The role of overweight and obesity in adverse cardiovascular disease mortality trends: an analysis of multiple cause of death data from Australia and the USA. BMC Med. 2020;18:199.
Yoon YH, Chen CM, Yi HY, Moss HB. Effect of comorbid alcohol and drug use disorders on premature death among unipolar and bipolar disorder decedents in the United States, 1999 to 2006. Compr Psychiatry. 2011;52:453–464.
Villela PB, Klein CH, Oliveira GMM. Cerebrovascular and hypertensive diseases as multiple causes of death in Brazil from 2004 to 2013. Public Health. 2018;161:36–42.
Barbieri M, Desesquelles A, Egidi V, et al. Obesity-related mortality in France, Italy, and the United States: a comparison using multiple cause-of-death analysis. Int J Public Health. 2017;62:623–629.
Alexander MJ, Kiang MV, Barbieri M. Trends in black and white opioid mortality in the United States, 1979-2015. Epidemiology. 2018;29:707–715.
Egidi V, Salvatore MA, Rivellini G, D’Angelo S. A network approach to studying cause-of-death interrelations. Demogr Res. 2018;38:373–400.
Jiang H, Wu H, Wang MD. Causes of death in the United States, 1999 to 2014. 2017 IEEE EMBS International Conference on Biomedical and Health Informatics, BHI. 2017;177–180.
Hassanzadeh HR, Sha Y, Wang MD. DeepDeath: Learning to predict the underlying cause of death with big data. 2017 39th Annual International Conference of the Ieee Engineering in Medicine and Biology Society. IEEE; 2017:3373–3376.
Moreno-Betancur M, Sadaoui H, Piffaretti C, Rey G. Survival analysis with multiple causes of death extending the competing risks model. Epidemiology. 2017;28:12–19.
Gonzalez LF, Jo AHS, Garcia CAR. Weighted mortality method according to multiple causes of death. Finlay. 2019;9:197–209.
Breger TL, Edwards JK, Cole SR, et al. Estimating a set of mortality risk functions with multiple contributing causes of death. Epidemiology. 2020;31:704–712.
Xie SH, Chen H, Lagergren J. Causes of death in patients diagnosed with gastric adenocarcinoma in Sweden, 1970-2014: a population-based study. Cancer Sci. 2020;111:2451–2459.
Bishop KA, Moreno-Betancur M, Balogun S, et al. Quantifying cause-related mortality in Australia incorporating multiple causes: observed patterns, trends, and practical considerations. Int J Epidemiology. 2022;52:284–294. doi: 10.1093/ije/dyac167.
doi: 10.1093/ije/dyac167
Rao C, Adair T, Bain C, Doi SA. Mortality from diabetic renal disease: a hidden epidemic. Eur J Public Health. 2011;22:280–284.
Lu TH, Hsu PY, Bjorkenstam C, Anderson RN. Certifying diabetes-related cause-of-death: a comparison of inappropriate certification statements in Sweden, Taiwan and the USA. Diabetologia. 2006;49:2878–2881.
Adair T, Rao C. Changes in certification of diabetes with cardiovascular diseases increased reported diabetes mortality in Australia and the United States. J Clin Epidemiol. 2010;63:199–204.
Trabsky M, Hempton C. “Died from” or “died with” COVID-19? We need a transparent approach to counting coronavirus deaths. Conversation. 2020. https://theconversation.com/died-from-or-died-with-covid-19-we-need-a-transparent-approach-to-counting-coronavirus-deaths-145438 .
Slater TA, Straw S, Drozd M, Kamalathasan S, Cowley A, Witte KK. Dying “due to” or “with” COVID-19: a cause of death analysis in hospitalised patients. Clin Med (Lond). 2020;20:e189–e190.
Oliver D. David Oliver: Mistruths and misunderstandings about COVID-19 death numbers. BMJ. 2021;372:n352.
Shiue KY, Naumann RB, Proescholdbell S, Cox ME, Aurelius M, Austin AE. Differences in overdose deaths by intent: unintentional & suicide drug poisonings in North Carolina, 2015-2019. Prev Med. 2022;163:107217.
Trinidad JP, Warner M, Bastian BA, Minino AM, Hedegaard H. Using literal text from the death certificate to enhance mortality statistics: characterizing drug involvement in deaths. Natl Vital Stat Rep. 2016;65:1–15.
Australian Bureau of Statistics. Psychosocial risk factors as they relate to coroner-referred deaths in Australia [Internet]. ABS; 2019.
Goldacre MJ, Duncan ME, Griffith M. Death rates for asthma in English populations 1979-2007: comparison of underlying cause and all certified causes. Public Health. 2012;126:386–393.
Jansson B, Ahmed N. Epilepsy and injury mortality in Sweden--the importance of changes in coding practice. Seizure. 2002;11:361–370.
Chitty KM, Schumann JL, Moran LL, Chong DG, Hurzeler TP, Buckley NA. Reporting of alcohol as a contributor to death in Australian national suicide statistics and its relationship to post-mortem alcohol concentrations. Addiction. 2021;116:506–513.
Kiadaliri AA, Petersson IF, Englund M. Educational inequalities in mortality associated with rheumatoid arthritis and other musculoskeletal disorders in Sweden. BMC Musculoskelet Disord. 2019;20:83.
Kiadaliri AA, Rosengren BE, Englund M. Fracture-related mortality in southern Sweden: a multiple cause of death analysis, 1998-2014. Injury. 2018;49:236–242.
Turner C, Chandrakumar D, Rowe C, Santos GM, Riley ED, Coffin PO. Cross-sectional cause of death comparisons for stimulant and opioid mortality in San Francisco, 2005-2015. Drug Alcohol Depend. 2018;185:305–312.
Parks SE, Kegler SR, Annest JL, Mercy JA. Characteristics of fatal abusive head trauma among children in the USA: 2003-2007: an application of the CDC operational case definition to national vital statistics data. Inj Prev. 2012;18:193–199.
Fedeli U, Grande E, Grippo F, Frova L. Mortality associated with hepatitis C and hepatitis B virus infection: a nationwide study on multiple causes of death data. World J Gastroenterol. 2017;23:1866–1871.
Ford MM, Desai PS, Maduro G, Laraque F. Neighborhood inequalities in Hepatitis C mortality: spatial and temporal patterns and associated factors. J Urban Health. 2017;94:746–755.
Grande E, Zucchetto A, Suligoi B, et al. Multiple cause-of-death data among people with AIDS in Italy: a nationwide cross-sectional study. Popul Health Metr. 2017;15:19.
Pechholdova M. Sepsis-related mortality in the Czech Republic: multiple causes of death analysis. Epidemiol Mikrobiol Imunol. 2017;66:73–79.
da Silva LR, Araújo ETH, Carvalho ML, et al. Epidemiological situation of acquired immunodeficiency syndrome (Aids)-related mortality in a municipality in northeastern brazil. a retrospective cross-sectional study. Sao Paulo Med J. 2018;136:37–43.
Duncan ME, Pitcher A, Goldacre MJ. Atrial fibrillation as a cause of death increased steeply in England between 1995 and 2010. Europace. 2014;16:797–802.
Garcia-Ptacek S, Kareholt I, Cermakova P, Rizzuto D, Religa D, Eriksdotter M. Causes of death according to death certificates in individuals with dementia: a cohort from the Swedish dementia registry. J Am Geriatr Soc. 2016;64:e137–e142.
Takamori A, Takahashi I, Kasagi F, Suyama A, Ozasa K, Yanagawa T. Mortality analysis of the Life Span Study (LSS) cohort taking into account multiple causes of death indicated in death certificates. Radiat Res. 2017;187:20–31.
Seuc AH, Fernandez-Gonzalez L, Mirabal M. Comparative disease assessment: a multi-causal approach for estimating the burden of mortality. J Public Health. 2020;30:665–673.
Amaral TLM, Amaral CA, Miranda Filho AL, Monteiro GTR. Trends and multiple causes of death due to chronic renal failure in a municipality in the Brazilian Amazon. Cien Saude Colet. 2018;23:3821–3828.
Fedeli U, Schievano E, Lisiero M, Avossa F, Mastrangelo G, Saugo M. Descriptive epidemiology of chronic liver disease in northeastern Italy: an analysis of multiple causes of death. Popul Health Metr. 2013;11:20.
Fedeli U, Schievano E, Targher G, Bonora E, Corti MC, Zoppini G. Estimating the real burden of cardiovascular mortality in diabetes. Eur Rev Med Pharmacol Sci. 2019;12:6700–6706.
Redelings MD, Lee NE, Sorvillo F. Pressure ulcers: more lethal than we thought? Adv Skin Wound Care. 2005;18:367–372.
Ramos AN Jr, Matida LH, Hearst N, Heukelbach J. Mortality in Brazilian children with HIV/AIDS: the role of non-AIDS-related conditions after highly active antiretroviral therapy introduction. AIDS Patient Care STDS. 2011;25:713–718.
Chang CY, Lu TH, Cheng TJ. Trends in reporting injury as a cause of death among people with epilepsy in the U.S., 1981-2010. Seizure. 2014;23:836–843.
Grippo F, Pappagallo M, Burgio A, Crialesi R. Drug induced mortality: a multiple cause approach on italian causes of death register. Epidemiol Biostat Public Health. 2015;12:e–1.
Laanani M, Viallon V, Coste J, Rey G. Collider and Reporting Biases Involved in the Analyses of Cause of Death Associations in Death Certificates: an Illustration with Cancer and Suicide. Prepr Res Square. 2021:1–18. doi:10.21203/rs.3.rs-377726/v1.
doi: 10.21203/rs.3.rs-377726/v1
Newcomer SR, Steiner JF, Bayliss EA. Identifying subgroups of complex patients with cluster analysis. Am J Manag Care. 2011;17:e324–e332.
Frova L, Salvatore MA, Pappagallo M, Egidi V. The multiple cause of death approach to analyse mortality patterns. Genus. 2009;65:1–21.
Roso-Llorach A, Violán C, Foguet-Boreu Q, et al. Comparative analysis of methods for identifying multimorbidity patterns: a study of ‘real-world’data. BMJ open. 2018;8:e018986.
Mabon K, Steinum O, Chute CG. Postcoordination of codes in ICD-11. BMC Med Inform Decis Mak. 2022;21(Suppl 6):379.
World Health Organization. International Classification of Diseases Eleventh Revision (ICD-11). World Health Organization; 2022.
Domingues CSB, Waldman EA. Causes of death among people living with AIDS in the Pre- and Post-HAART eras in the city of S(a)over-tildeo Paulo, Brazil. PLoS One. 2014;9:e114661e114661.
Goldstein E, Lipsitch M. The relation between prescribing of different antibiotics and rates of mortality with sepsis in US adults. BMC Infect Dis. 2020;20:169.
World Health Organization. International Guidleines for Certification and Classification (Coding) of COVID-19 as Cause of Death. World Health Organization; 2020.
Grippo F, Navarra S, Orsi C, et al.; Italian National Institute of Health Covid-Mortality G. The role of COVID-19 in the death of SARS-CoV-2-positive patients: a study based on death certificates. J Clin Med. 2020;9:3459.
Christensen RAG, Arneja J, St Cyr K, Sturrock SL, Brooks JD. The association of estimated cardiorespiratory fitness with COVID-19 incidence and mortality: a cohort study. PLoS One. 2021;16:e0250508.
Nogales Vasconcelos AM, Ishitani L, Abreu DMX, Franca E. Covid adult mortality in Brazil: an analysis of multiple causes of death. Front Public Health. 2021;9:788932.
Woodward M, Peters SAE, Harris K. Social deprivation as a risk factor for COVID-19 mortality among women and men in the UK Biobank: nature of risk and context suggests that social interventions are essential to mitigate the effects of future pandemics. J Epidemiol Community Health. 2021;75:1050–1055.
Grippo F, Grande E, Maraschini A, et al.; Italian National Institute of Health C-MG. Evolution of pathology patterns in persons who died from COVID-19 in Italy: a national study based on death certificates. Front Med (Lausanne). 2021;8:645543.
Woolf SH, Chapman DA, Lee JH. COVID-19 as the leading cause of death in the United States. JAMA. 2021;325:123–124.