Hepatic Small Vessel Neoplasm Mimics Prostate Cancer on 18 F-DCFPyl PET/CT.


Journal

Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109

Informations de publication

Date de publication:
01 Apr 2023
Historique:
pubmed: 3 2 2023
medline: 4 3 2023
entrez: 2 2 2023
Statut: ppublish

Résumé

18 F-DCFPyl is a Food and Drug Administration-approved radiotracer that targets prostate-specific membrane antigen and is used in the detection of recurrent or metastatic prostate cancer. As its use has increased, a growing number of nonprostatic disease entities have been identified that express prostate-specific membrane antigen and can mimic prostate cancer. Thus, the interpreting physician must also consider other variables such as serum prostate-specific antigen levels and the distribution of uptake to avoid an inappropriate diagnosis of metastatic prostate cancer. We describe 18 F-DCFPyl uptake associated with a hepatic small vessel neoplasm, an association previously undescribed in the literature.

Identifiants

pubmed: 36728165
doi: 10.1097/RLU.0000000000004554
pii: 00003072-202304000-00039
doi:

Substances chimiques

Lysine K3Z4F929H6
Radiopharmaceuticals 0
Urea 8W8T17847W

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e181-e183

Informations de copyright

Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of interest and sources of funding: none declared.

Références

de Galiza Barbosa F, Queiroz MA, Nunes RF, et al. Nonprostatic diseases on PSMA PET imaging: a spectrum of benign and malignant findings. Cancer Imaging . 2020;20:23.
Gill RM, Buelow B, Mather C, et al. Hepatic small vessel neoplasm, a rare infiltrative vascular neoplasm of uncertain malignant potential. Hum Pathol . 2016;54:143–151.
Joseph NM, Brunt EM, Marginean C, et al. Frequent GNAQ and GNA14 mutations in hepatic small vessel neoplasm. Am J Surg Pathol . 2018;9:1201–1207.
Rangaswamy B, Minervini M, Tublin M, et al. Imaging and pathologic findings of hepatic small vessel hemangioma. Curr Probl Diagn Radiol . 2019;48:626–628.
Goh IY, Mulholland P, Sokolova A, et al. Hepatic small vessel neoplasm—a systematic review. Ann Med Surg (Lond) . 2021;72:103004.
Paisant A, Bellal S, Lebigot J, et al. Imaging features of hepatic small vessel neoplasm: case series. Hepatology . 2021;74:2894–2896.
Brazão ÉS, Ribeiro AMB, Lima ENP, et al. False-positive uptake in splenic hemangioma on 68 Ga-PSMA PET/CT scan for late biochemical recurrence of prostate cancer. Clin Nucl Med . 2021;47:e14–e16.
Cicala CM, Monaca F, Giustiniani MC, et al. Multifocal hepatic small vessel neoplasm with spleen dissemination. BMJ Case Rep . 2022;15:e248785.

Auteurs

Keith L Spinali (KL)

From the Departments of Radiology.

David J Papke (DJ)

Pathology, Brigham and Women's Hospital.

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Classifications MeSH