Intraocular Fibrin Glue to Lower the Risk of Postoperative Vitreous Hemorrhage After Diabetic Pars Plana Vitrectomy.


Journal

Retina (Philadelphia, Pa.)
ISSN: 1539-2864
Titre abrégé: Retina
Pays: United States
ID NLM: 8309919

Informations de publication

Date de publication:
01 Dec 2023
Historique:
medline: 22 11 2023
pubmed: 3 2 2023
entrez: 2 2 2023
Statut: ppublish

Résumé

To investigate the use of intraocular fibrin glue to lower the risk of vitreous hemorrhage (VH) after pars plana vitrectomy (PPV) in eyes with diabetic VH or traction retinal detachment. A matched, case-control, single-surgeon, pilot study of patients undergoing PPV for diabetic VH or traction retinal detachment with versus without fibrin glue was performed. Thirty-nine patients (13 glue and 26 control patients) were included. In the glue group, mean (SD) logarithm of the minimum angle of resolution visual acuity (Snellen) significantly improved from 1.53 (0.6) (20/678) to 0.99 (0.9) (20/195) at postoperative month 6 ( P = 0.03). In the control group, mean logarithm of the minimum angle of resolution visual acuity also improved from 1.45 (0.8) (20/564) to 1.17 (0.9) (20/296) at postoperative Month 6 ( P = 0.3). Persistent post-PPV VH was similar between the 2 groups (15.4% in both groups, P > 0.99). However, early recurrent VH (<3 months post-PPV) was seen in 34.6% in the control group and none in the glue group ( P = 0.02). No intraocular inflammatory events were seen in the glue group. Intraocular fibrin glue may be a safe adjuvant in diabetic vitrectomy and may reduce the rate of early recurrent postoperative VH.

Identifiants

pubmed: 36731110
doi: 10.1097/IAE.0000000000003597
pii: 00006982-990000000-00122
doi:

Substances chimiques

Fibrin Tissue Adhesive 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2148-2152

Références

Machemer R, Buettner H, Norton EW, Parel JM. Vitrectomy: a pars plana approach. Trans Am Acad Ophthalmol Otolaryngol 1971;75:813–820.
Stewart MW, Browning DJ, Landers MB. Current management of diabetic tractional retinal detachments. Indian J Ophthalmol 2018;66:1751–1762.
El Annan J, Carvounis PE. Current management of vitreous hemorrhage due to proliferative diabetic retinopathy. Int Ophthalmol Clin 2014;54:141–153.
Khuthaila MK, Hsu J, Chiang A, et al. Postoperative vitreous hemorrhage after diabetic 23-gauge pars plana vitrectomy. Am J Ophthalmol 2013;155:757–763.
Brown GC, Tasman WS, Benson WE, et al. Reoperation following diabetic vitrectomy. Arch Ophthalmol 1992;110:506–510.
Panda A, Kumar S, Kumar A, et al. Fibrin glue in ophthalmology. Indian J Ophthalmol 2009;57:371–379.
Olsen TW, Sternberg P Jr, Capone A Jr, et al. Macular hole surgery using thrombin-activated fibrinogen and selective removal of the internal limiting membrane. Retina 1998;18:322–329.
Al Sabti K, Kumar N, Chow DR, Kapusta MA. Management of optic disk pit-associated macular detachment with tisseel fibrin sealant. Retin Cases Brief Rep 2008;2:274–277.
Tyagi M, Basu S. Glue-assisted retinopexy for rhegmatogenous retinal detachments (GuARD): a novel surgical technique for closing retinal breaks. Indian J Ophthalmol 2019;67:677–680.
Schachat AP, Oyakawa RT, Michels RG, Rice TA. Complications of vitreous surgery for diabetic retinopathy. II. Postoperative complications. Ophthalmology 1983;90: 522–530.
Al-Khersan H, Venincasa MJ, Kloosterboer A, et al. Pars plana vitrectomy reoperations for complications of proliferative diabetic retinopathy. Clin Ophthalmol 2020;14:1559–1563.
Bastiaans J, van Meurs JC, Mulder VC, et al. The role of thrombin in proliferative vitreoretinopathy. Invest Ophthalmol Vis Sci 2014;55:4659–4666.

Auteurs

Hana A Mansour (HA)

Wills Eye Hospital, Mid Atlantic Retina, Thomas Jefferson University, Philadelphia, Pennsylvania.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH