Polysaccharides from the hard shells of Juglans regia L. modulate intestinal function and gut microbiota in vivo.

Animals Mice Gastrointestinal Microbiome Juglans Polysaccharides / pharmacology Colon Intestines
Gut microbiota Intestinal function Juglans regia L. Metabolism Polysaccharides

Journal

Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639

Informations de publication

Date de publication:
30 Jun 2023
Historique:
received: 19 03 2022
revised: 25 12 2022
accepted: 26 01 2023
pubmed: 4 2 2023
medline: 7 3 2023
entrez: 3 2 2023
Statut: ppublish

Résumé

This study aimed to investigate the modulatory effects of polysaccharides from the hard shells ofJuglans regiaL. (JRP) on intestinal function and gut microbiota of mice. The results showed that JRP could increase the colonic length and colonic index, and ameliorate the histological characteristics of colon. JRP had a positive effect on immunity of mice by improving immune organ indexes. Owing to enhancement of intestinal peristalsis and increase of colonic fecal moisture by JRP, the defecation time was significantly reduced. After gastrointestinal digestion and absorption, JRP was metabolized by intestinal microorganisms to produce short chain fatty acids, thereby lowering the pH of intestine. Through microbial community analysis, the composition of gut microbiota was modulated by JRPvia increasing theabundances of beneficial bacteriaand decreasing the richness of harmful bacteria. This study suggests that JRP can be served as an excellent prebiotic to promote intestinal health.

Identifiants

DOI: 10.1016/j.foodchem.2023.135592 PMID: 36736188
pubmed: 36736188
pii: S0308-8146(23)00208-X
doi: 10.1016/j.foodchem.2023.135592
pii:
doi:

Substances chimiques

Polysaccharides 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

135592

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Xiaoyu Li (X)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China.

Siying An (S)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China.

Zhen Luo (Z)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China.

Peng Zhou (P)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China.

Lu Wang (L)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China. Electronic address: wl@ysu.edu.cn.

Ru Feng (R)

Nano-biotechnology Key Laboratory of Hebei Province, Skate Key Laboratory of Metastable Materials Science and Technology, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004, PR China.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Polysaccharides from the hard shells of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Polysaccharides from the hard shells of...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Polysaccharides from the hard shells of...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Rosanae › Fagales › Juglandaceae › Juglans › Polysaccharides from the hard shells of...
questionsmedicales.fr › Glucides › Polyosides › Polysaccharides from the hard shells of...
questionsmedicales.fr › Système digestif › Tube digestif › Tube digestif inférieur › Gros intestin › Côlon › Polysaccharides from the hard shells of...
questionsmedicales.fr › Système digestif › Tube digestif › Intestins › Polysaccharides from the hard shells of...