Triterpenoids from the leaves of Abies koreana and their biological activities.

Triterpenes / chemistry Abies / chemistry Molecular Structure Magnetic Resonance Spectroscopy Plant Leaves
Abies koreana Anti-neuroinflammation Cytotoxic Neurotrophic Pinaceae Triterpenoid

Journal

Phytochemistry
ISSN: 1873-3700
Titre abrégé: Phytochemistry
Pays: England
ID NLM: 0151434

Informations de publication

Date de publication:
Apr 2023
Historique:
received: 07 12 2022
revised: 23 01 2023
accepted: 24 01 2023
pubmed: 5 2 2023
medline: 8 3 2023
entrez: 4 2 2023
Statut: ppublish

Résumé

Seven undescribed triterpenoids, abikoranes A-G, along with three known triterpenoids were isolated from the leaves of Abies koreana E. H. Wilson. The structures of compounds were elucidated by 1D and 2D NMR, HRMS, ECD, specific rotation, and DP4+ analysis. Abikorane A represents the second example of nor-3,4-seco-17,14-friedo-lanostane triterpenoid. Among the isolates, some compounds showed strong cytotoxic activities against some of four tested cancer cell lines (A549, SK-OV-3, SK-MEL-2, and HCT-116) with the values of IC

Identifiants

DOI: 10.1016/j.phytochem.2023.113594 PMID: 36738908
pubmed: 36738908
pii: S0031-9422(23)00010-9
doi: 10.1016/j.phytochem.2023.113594
pii:
doi:

Substances chimiques

Triterpenes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113594

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Dong Jun Lee (DJ)

Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: ldj950110@skku.edu.

Seong-Min Hong (SM)

Gachon Institute of Pharmaceutical Science, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea. Electronic address: hongsm0517@gmail.com.

Da Hye Yoon (DH)

Gachon Institute of Pharmaceutical Science, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea. Electronic address: yoon29100@naver.com.

Song Lim Ham (SL)

Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: songlim0824@skku.edu.

Jonghwan Kim (J)

Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea.

Sun Yeou Kim (SY)

Gachon Institute of Pharmaceutical Science, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea; College of Pharmacy, Gachon University, 191 Hambakmoero, Yeonsu-gu, Incheon, 21936, Republic of Korea. Electronic address: sunnykim@gachon.ac.kr.

Sang Un Choi (SU)

Korea Research Institute of Chemical Technology, Daejeon, 34114, Republic of Korea. Electronic address: suchoi@krict.re.kr.

Chung Sub Kim (CS)

Department of Biopharmaceutical Convergence, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: chungsub.kim@skku.edu.

Kang Ro Lee (KR)

Natural Products Laboratory, School of Pharmacy, Sungkyunkwan University, Suwon, 16419, Republic of Korea. Electronic address: krlee@skku.edu.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Terpènes › Triterpènes › Triterpenoids from the leaves of Abies koreana...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Pinales › Pinaceae › Abies › Triterpenoids from the leaves of Abies koreana...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Triterpenoids from the leaves of Abies koreana...
questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Analyse spectrale › Spectroscopie par résonance magnétique › Triterpenoids from the leaves of Abies koreana...
questionsmedicales.fr › Structures de plante › Parties aériennes de plante › Feuilles de plante › Triterpenoids from the leaves of Abies koreana...