Pectin-based aerogel particles for drug delivery: Effect of pectin composition on aerogel structure and release properties.
Beads
Carriers
Molecular weight
Release kinetics
Vanillin
Journal
Carbohydrate polymers
ISSN: 1879-1344
Titre abrégé: Carbohydr Polym
Pays: England
ID NLM: 8307156
Informations de publication
Date de publication:
15 Apr 2023
15 Apr 2023
Historique:
received:
29
09
2022
revised:
09
01
2023
accepted:
16
01
2023
entrez:
6
2
2023
pubmed:
7
2
2023
medline:
9
2
2023
Statut:
ppublish
Résumé
In this work, nanostructured pectin aerogels were prepared via a sol-gel process and subsequent drying under supercritical conditions. To this end, three commercially available citrus pectins and an in-house produced and enzymatically modified watermelon rind pectin (WRP) were compared. Then, the effect of pectin's structure and composition on the aerogel properties were analysed and its potential application as a delivery system was explored by impregnating them with vanillin. Results showed that the molecular weight, degree of esterification and branching degree of the pectin samples played a main role in the production of hydrogels and subsequent aerogels. The developed aerogel particles showed high specific surface areas (468-584 m
Identifiants
pubmed: 36746590
pii: S0144-8617(23)00068-1
doi: 10.1016/j.carbpol.2023.120604
pii:
doi:
Substances chimiques
vanillin
CHI530446X
Drug Carriers
0
Pectins
89NA02M4RX
Hydrogels
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
120604Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.