Structural mechanisms for the activation of human cardiac KCNQ1 channel by electro-mechanical coupling enhancers.


Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
08 11 2022
Historique:
entrez: 10 2 2023
pubmed: 11 2 2023
medline: 15 2 2023
Statut: ppublish

Résumé

The cardiac KCNQ1 potassium channel carries the important

Identifiants

pubmed: 36763058
doi: 10.1073/pnas.2207067119
pmc: PMC9661191
doi:

Substances chimiques

(R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide 0
KCNQ1 Potassium Channel 0
Piperidines 0
KCNQ1 protein, human 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2207067119

Références

Cell. 2020 Jan 23;180(2):340-347.e9
pubmed: 31883792
Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):868-77
pubmed: 22895603
Nat Genet. 1996 Jan;12(1):17-23
pubmed: 8528244
Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:447-464
pubmed: 34516289
Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6109-14
pubmed: 21444776
J Gen Physiol. 2021 Dec 6;153(12):
pubmed: 34636894
J Gen Physiol. 2021 Jun 7;153(6):
pubmed: 33939797
Handb Exp Pharmacol. 2021;267:185-230
pubmed: 33860384
Proc Natl Acad Sci U S A. 2015 May 5;112(18):5714-9
pubmed: 25901329
Mol Pharmacol. 2020 Feb;97(2):132-144
pubmed: 31722973
J Mol Graph. 1996 Dec;14(6):354-60, 376
pubmed: 9195488
Commun Biol. 2020 Jul 16;3(1):385
pubmed: 32678288
Elife. 2020 Feb 25;9:
pubmed: 32096762
Nat Rev Neurosci. 2000 Oct;1(1):21-30
pubmed: 11252765
Circ Res. 2006 Apr 28;98(8):1055-63
pubmed: 16556865
Nature. 2016 Sep 1;537(7618):117-121
pubmed: 27556947
Nat Commun. 2017 Nov 23;8(1):1730
pubmed: 29167462
J Gen Physiol. 2018 Feb 5;150(2):307-321
pubmed: 29321262
Elife. 2019 Jul 22;8:
pubmed: 31329101
Cell. 2017 Jun 1;169(6):1042-1050.e9
pubmed: 28575668
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8732-7
pubmed: 23650380
Elife. 2014 Dec 23;3:e03606
pubmed: 25535795
Nature. 1980 Feb 14;283(5748):673-6
pubmed: 6965523
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6444-9
pubmed: 21464282
Nat Chem Biol. 2007 May;3(5):287-96
pubmed: 17435769
Mol Pharmacol. 1998 Jul;54(1):220-30
pubmed: 9658209
EMBO J. 1999 Aug 2;18(15):4137-48
pubmed: 10428953
Heart Rhythm. 2018 Oct;15(10):1566-1574
pubmed: 29857160
J Physiol. 2007 Dec 1;585(Pt 2):325-37
pubmed: 17932138
Biophys J. 1994 Apr;66(4):1011-21
pubmed: 8038375
Nat Commun. 2022 Jun 29;13(1):3760
pubmed: 35768468
Commun Biol. 2022 Apr 1;5(1):301
pubmed: 35365746
Bioorg Med Chem Lett. 2012 Sep 15;22(18):5936-41
pubmed: 22910039
Circ Res. 2006 Apr 28;98(8):1048-54
pubmed: 16556866
Stem Cell Res Ther. 2015 Mar 19;6:39
pubmed: 25889101
Mol Cell. 2021 Jan 7;81(1):25-37.e4
pubmed: 33238160
Circ Res. 2003 Nov 14;93(10):941-7
pubmed: 14576198
Cell. 2019 May 30;177(6):1495-1506.e12
pubmed: 31150622
Circ Res. 2007 Mar 16;100(5):686-92
pubmed: 17293474
Nature. 1996 Nov 7;384(6604):80-3
pubmed: 8900283
Nat Commun. 2020 Feb 3;11(1):676
pubmed: 32015334
Proc Natl Acad Sci U S A. 2013 Aug 6;110(32):13180-5
pubmed: 23861489
Neuron. 2022 Jan 19;110(2):237-247.e4
pubmed: 34767770
Biophys J. 2015 Jan 6;108(1):62-75
pubmed: 25564853
Physiol Rev. 2017 Jan;97(1):89-134
pubmed: 27807201
Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11102-6
pubmed: 19549851
J Struct Biol. 2005 Oct;152(1):36-51
pubmed: 16182563
J Biol Chem. 2008 Aug 15;283(33):22649-58
pubmed: 18490447
Proc Natl Acad Sci U S A. 2021 May 18;118(20):
pubmed: 33990467
Sci Adv. 2018 Nov 14;4(11):eaav0824
pubmed: 30443601
Nature. 1996 Nov 7;384(6604):78-80
pubmed: 8900282
Science. 2010 Apr 2;328(5974):67-73
pubmed: 20360102
Cell Res. 2021 Jan;31(1):52-61
pubmed: 32884139
Handb Exp Pharmacol. 2021;267:231-251
pubmed: 33837465

Auteurs

Demin Ma (D)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Ling Zhong (L)

Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.

Zhenzhen Yan (Z)

Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.

Jing Yao (J)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Yan Zhang (Y)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Fan Ye (F)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Yuan Huang (Y)

Department of Cardiology, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.

Dongwu Lai (D)

Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Sir Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.

Wei Yang (W)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China.
NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, 310058, China.

Panpan Hou (P)

Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.

Jiangtao Guo (J)

Department of Biophysics, and Department of Neurology of the Fourth Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Department of Cardiology, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Sir Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China.
Liangzhu Laboratory, Zhejiang University Medical Center, Hangzhou, 311121, China.
NHC and CAMS Key Laboratory of Medical Neurobiology, MOE Frontier Science Center for Brain Science and Brain-Machine Integration, School of Brain Science and Brain Medicine, Zhejiang University, 310058, China.
State Key Laboratory of Plant Physiology and Biochemistry, College of Life Sciences, Zhejiang University, Hangzhou, 310058, China.
Cancer Center, Zhejiang University, Hangzhou, 310058, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH