iVirus 2.0: Cyberinfrastructure-supported tools and data to power DNA virus ecology.
Journal
ISME communications
ISSN: 2730-6151
Titre abrégé: ISME Commun
Pays: England
ID NLM: 9918205372406676
Informations de publication
Date de publication:
14 Dec 2021
14 Dec 2021
Historique:
received:
20
09
2021
accepted:
29
11
2021
revised:
24
11
2021
entrez:
10
2
2023
pubmed:
14
12
2021
medline:
14
12
2021
Statut:
epublish
Résumé
Microbes drive myriad ecosystem processes, but under strong influence from viruses. Because studying viruses in complex systems requires different tools than those for microbes, they remain underexplored. To combat this, we previously aggregated double-stranded DNA (dsDNA) virus analysis capabilities and resources into 'iVirus' on the CyVerse collaborative cyberinfrastructure. Here we substantially expand iVirus's functionality and accessibility, to iVirus 2.0, as follows. First, core iVirus apps were integrated into the Department of Energy's Systems Biology KnowledgeBase (KBase) to provide an additional analytical platform. Second, at CyVerse, 20 software tools (apps) were upgraded or added as new tools and capabilities. Third, nearly 20-fold more sequence reads were aggregated to capture new data and environments. Finally, documentation, as "live" protocols, was updated to maximize user interaction with and contribution to infrastructure development. Together, iVirus 2.0 serves as a uniquely central and accessible analytical platform for studying how viruses, particularly dsDNA viruses, impact diverse microbial ecosystems.
Identifiants
pubmed: 36765102
doi: 10.1038/s43705-021-00083-3
pii: 10.1038/s43705-021-00083-3
pmc: PMC9723767
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
77Subventions
Organisme : NSF | BIO | Division of Biological Infrastructure (DBI)
ID : DBI-1743442
Organisme : DOE | Office of Science (SC)
ID : SCW1632
Organisme : DOE | Office of Science (SC)
ID : SCW1656
Organisme : DOE | Office of Science (SC)
ID : DE-AC52-07NA27344
Organisme : DOE | Office of Science (SC)
ID : DE-AC02-05CH11231
Organisme : National Science Foundation (NSF)
ID : 1663578
Informations de copyright
© 2021. The Author(s).
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