Suspect Screening of Chemicals in Hospital Wastewaters Using Effect-Directed Analysis Approach as Prioritization Strategy.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
26 Jan 2023
Historique:
received: 22 12 2022
revised: 18 01 2023
accepted: 19 01 2023
entrez: 11 2 2023
pubmed: 12 2 2023
medline: 15 2 2023
Statut: epublish

Résumé

The increasing number of contaminants in the environment has pushed water monitoring programs to find out the most hazardous known and unknown chemicals in the environment. Sample treatment-simplification methods and non-target screening approaches can help researchers to not overlook potential chemicals present in complex aqueous samples. In this work, an effect-directed analysis (EDA) protocol using the sea urchin embryo test (SET) as a toxicological in vivo bioassay was used as simplified strategy to identify potential unknown chemicals present in a very complex aqueous matrix such as hospital effluent. The SET bioassay was used for the first time here to evaluate potential toxic fractions in hospital effluent, which were obtained after a two-step fractionation using C

Identifiants

pubmed: 36770879
pii: molecules28031212
doi: 10.3390/molecules28031212
pmc: PMC9921743
pii:
doi:

Substances chimiques

Wastewater 0
Water Pollutants, Chemical 0
Water 059QF0KO0R

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Agencia Estatal de Investigación of Spain
ID : CTM2017-84763-C3-1-R
Organisme : European Regional Development Fund
ID : CTM2017-84763-C3-1-R
Organisme : Agencia Estatal de Investigación of Spain
ID : CTM2020-117686RB-C31
Organisme : European Regional Development Fund
ID : CTM2020-117686RB-C31
Organisme : Basque Research System
ID : IT1213-19
Organisme : Spanish Ministry of Economy, Industry and Competitivity
ID : PRE2018-086493
Organisme : University of the Basque Country
Organisme : University of Pau and Pays de l'Adour
Organisme : Ministry of Science, Innovation and Universities
ID : CTM2017-90890-REDT

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Auteurs

Naroa Lopez-Herguedas (N)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Leire Mijangos (L)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Iker Alvarez-Mora (I)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Belén González-Gaya (B)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Teresa Uribe-Echeverria (T)

Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Nestor Etxebarria (N)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Olatz Zuloaga (O)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Maitane Olivares (M)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

Ailette Prieto (A)

Department of Analytical Chemistry, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), 48940 Leioa, Basque Country, Spain.
Research Centre for Experimental Marine Biology and Biotechnology (PIE), University of the Basque Country (UPV/EHU), 48620 Plentzia, Basque Country, Spain.

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Classifications MeSH