Impact of postoperative intravenous iron therapy on postoperative infections in older patients with severe anaemia after hip fracture surgery.
Geriatric patients
Intravenous iron
Postoperative anaemia
Postoperative infections
Surgery
Journal
BMC geriatrics
ISSN: 1471-2318
Titre abrégé: BMC Geriatr
Pays: England
ID NLM: 100968548
Informations de publication
Date de publication:
14 02 2023
14 02 2023
Historique:
received:
27
06
2022
accepted:
27
01
2023
entrez:
15
2
2023
pubmed:
16
2
2023
medline:
17
2
2023
Statut:
epublish
Résumé
Anaemia is common following hip fracture in ortho-geriatric patients and is associated with postoperative infections.. This study investigated whether intravenous iron supplements reduced the rate of postoperative infections within 30 days postoperatively in older adults after hip fracture surgery. This observational study included 198 ortho-geriatric patients July 2018-May 2020. In May 2019 a local guideline was implemented and recommended II therapy on the 3 The patients were divided into four treatment groups: blood transfusion (n = 44), IV iron (n = 69), blood transfusion + IV iron (n = 35) and no treatment (n = 50). The number of patients who had an infection within 30 days was similar in the two time periods (38.8% before vs. 38.9% after systematic I.V. iron supplementation, P = 1.00) and no significant difference according to risk of infection was found between treatment groups. This study documents no effect of intravenous iron supplements on postoperative infections in older adults after hip fracture surgery. The study was registered with the Danish Data Protection Authority (2008-58-0028) the 2
Sections du résumé
BACKGROUND
Anaemia is common following hip fracture in ortho-geriatric patients and is associated with postoperative infections.. This study investigated whether intravenous iron supplements reduced the rate of postoperative infections within 30 days postoperatively in older adults after hip fracture surgery.
METHODS
This observational study included 198 ortho-geriatric patients July 2018-May 2020. In May 2019 a local guideline was implemented and recommended II therapy on the 3
RESULTS
The patients were divided into four treatment groups: blood transfusion (n = 44), IV iron (n = 69), blood transfusion + IV iron (n = 35) and no treatment (n = 50). The number of patients who had an infection within 30 days was similar in the two time periods (38.8% before vs. 38.9% after systematic I.V. iron supplementation, P = 1.00) and no significant difference according to risk of infection was found between treatment groups.
CONCLUSION
This study documents no effect of intravenous iron supplements on postoperative infections in older adults after hip fracture surgery.
TRIAL REGISTRATION
The study was registered with the Danish Data Protection Authority (2008-58-0028) the 2
Identifiants
pubmed: 36788483
doi: 10.1186/s12877-023-03775-8
pii: 10.1186/s12877-023-03775-8
pmc: PMC9930316
doi:
Substances chimiques
perferryl iron
14127-54-9
Iron
E1UOL152H7
Types de publication
Observational Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
95Informations de copyright
© 2023. The Author(s).
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