Plasma Cell Vulvitis: A Case Series and Follow-Up Study.


Journal

Journal of lower genital tract disease
ISSN: 1526-0976
Titre abrégé: J Low Genit Tract Dis
Pays: United States
ID NLM: 9704963

Informations de publication

Date de publication:
01 Apr 2023
Historique:
pubmed: 17 2 2023
medline: 28 3 2023
entrez: 16 2 2023
Statut: ppublish

Résumé

Plasma cell vulvitis (PCV) is a rare inflammatory vulvar condition. The aim of this study was to describe the natural history, treatment, impact on quality of life, and factors associated with poorer outcomes for PCV. A mixed-methods approach was used combining a retrospective case note review with a cross-sectional telephone questionnaire. All women diagnosed with PCV attending the vulvar disorders clinic at the Royal Women's Hospital between January 2011 and December 2020 were included. During the 10-year study period, 7,500 women were seen at the vulval disorders clinic, of whom 21 were diagnosed with PCV (0.28%). Of these women, 12 who were followed up for more than 12 months agreed to participate in the study. At a median of 5 years follow-up, there was variability in symptom severity, with more than half of the women still symptomatic with pain, precipitated by friction and dyspareunia, resulting in a moderate to large impact on quality of life. There were 5 women who were asymptomatic. Only 1 woman had a preexisting history of lichen planus and lichen sclerosus. Potent topical corticosteroids were identified as the preferred treatment. Women with PCV can remain symptomatic for many years with significant impacts on quality of life, which may consequently require long-term support and follow-up.

Identifiants

pubmed: 36794759
doi: 10.1097/LGT.0000000000000725
pii: 00128360-202304000-00014
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

185-189

Informations de copyright

Copyright © 2023, ASCCP.

Déclaration de conflit d'intérêts

The authors have declared they have no conflicts of interest.

Références

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Auteurs

Jennifer Nguyen (J)

Vulval Disorders Clinic, The Royal Women's Hospital, Parkville, Victoria, Australia.

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