Geographic Expansion of Japanese Encephalitis Virus to Australia: Neuroinflammatory Sequelae and Consideration of Immunomodulation.
Journal
The Pediatric infectious disease journal
ISSN: 1532-0987
Titre abrégé: Pediatr Infect Dis J
Pays: United States
ID NLM: 8701858
Informations de publication
Date de publication:
01 05 2023
01 05 2023
Historique:
medline:
14
4
2023
pubmed:
17
2
2023
entrez:
16
2
2023
Statut:
ppublish
Résumé
We report a child from Southern Australia (New South Wales) who presented during a La Niña event with encephalopathy and acute flaccid paralysis. Magnetic resonance imaging suggested Japanese encephalitis (JE). Steroids and intravenous immunoglobulin did not improve symptoms. Therapeutic plasma exchange (TPE) resulted in rapid improvement and tracheostomy decannulation. Our case illustrates the complex pathophysiology of JE, its' geographic expansion into Southern Australia and potential use of TPE for neuroinflammatory sequelae.
Identifiants
pubmed: 36795573
doi: 10.1097/INF.0000000000003861
pii: 00006454-202305000-00024
doi:
Substances chimiques
Steroids
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e173-e176Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors have no funding or conflicts of interest to disclose.
Références
Pierson TC, Diamond MS. The continued threat of emerging flaviviruses. Nat Microbiol. 2020;5:796–812.
Van den Hurk AF, Skinner E, Ritchie SA, et al. The emergence of Japanese encephalitis virus in Australia in 2022: existing knowledge of mosquito vectors. Viruses. 2022;14:1208.
Ashraf U, Ding Z, Deng S, et al. Pathogenicity and virulence of Japanese encephalitis virus: neuroinflammation and neuronal cell damage. Virulence. 2021;12:968–980.
Turtle L, Solomon T. Japanese encephalitis - the prospects for new treatments. Nat Rev Neurol. 2018;14:298–313.
Hills SS, Martínez D, Kim PY, et al. A case series of three US adults with Japanese encephalitis, 2010-2012. J Travel Med. 2014;21:310–313.
Schröder A, Linker RA, Gold R. Plasmapheresis for neuroinflammatory disorders. Clin Exp Immunol. 2010;1:95–102.
Care AGDoHaA. Japanese encephalitis virus Canberra 2022. [cited 2022 20/09/2022]. Available at: https://www.health.gov.au/health-alerts/japanese-encephalitis-virus-jev/about .
Grewe S, Gliem M, Abrar DB, et al. Myelitis with flaccid paralysis due to Japanese encephalitis: case report and review of the literature. Infection. 2022;50:1597–1603.
Pichl T, Wedderburn CJ, Hoskote C, et al. A systematic review of brain imaging findings in neurological infection with Japanese encephalitis virus compared with dengue virus. Int J Infect Dis. 2022;119:102–110.
Zang Q, Wang Y, Guo J, et al. Treatment of severe Japanese encephalitis complicated with Hashimoto’s thyroiditis and Guillain-Barré syndrome with protein A immunoadsorption: a case report. Front Immunol. 2021;12:807937.