Curalin supplement for patients with type 2 diabetes mellitus.
add-on therapy
natural herbal plants
supplement
type 2 diabetes
Journal
Diabetes/metabolism research and reviews
ISSN: 1520-7560
Titre abrégé: Diabetes Metab Res Rev
Pays: England
ID NLM: 100883450
Informations de publication
Date de publication:
05 2023
05 2023
Historique:
revised:
10
02
2023
received:
20
01
2023
accepted:
14
02
2023
medline:
8
5
2023
pubmed:
17
2
2023
entrez:
16
2
2023
Statut:
ppublish
Résumé
To examine the efficacy and safety of Curalin supplement in patients with type 2 diabetes. Adult patients with type 2 diabetes were randomized 1:1 to receive Curalin supplement or placebo. The primary endpoint was HbA1c decrease at 1 month. The secondary endpoint was a decrease in HbA1c by more than 0.5% and 1% and a change in 7 daily blood glucose measurements. A satisfaction questionnaire was used as an exploratory endpoint. Safety variables and adverse events were assessed. After 1 month of intervention, HbA1c was reduced by 0.94% in the Curalin arm versus 0.4% in the placebo arm (P = 0.008). 72% of Curalin patients had decreased HbA1c levels >0.5% versus 35% in the placebo arm (P < 0.05). The Treatment Satisfaction Questionnaire indicated that Curalin arm patients reported higher overall satisfaction. Curalin treatment significantly reduced HbA1c over a 1-month period and was well-tolerated.
Substances chimiques
Hypoglycemic Agents
0
Glycated Hemoglobin
0
Blood Glucose
0
Types de publication
Randomized Controlled Trial
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e3624Informations de copyright
© 2023 Curalife Ltd and The Authors. Diabetes/Metabolism Research and Reviews published by John Wiley & Sons Ltd.
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