The Ratio of Clavicle Length to Head Circumference: A Novel Date-Independent Clavicle Index.
Journal
Ultrasound quarterly
ISSN: 1536-0253
Titre abrégé: Ultrasound Q
Pays: United States
ID NLM: 8809459
Informations de publication
Date de publication:
01 Sep 2023
01 Sep 2023
Historique:
medline:
4
9
2023
pubmed:
22
2
2023
entrez:
21
2
2023
Statut:
epublish
Résumé
We aimed to plot the growth curve of the fetal clavicle, identify gestational date-independent parameters. Using 2-dimensional ultrasonography, we obtained the clavicle lengths (CLs) from 601 normal fetuses between 12 and 40 gestational age (GA). The CL/fetal growth parameters ratio was calculated. Moreover, 27 cases of fetal growth restriction (FGR) and 9 cases of small for GA (SGA) were detected. In normal fetuses, the mean CL (mm) = -68.2 + 29.80 × ln(GA) ± Z × (1.07 + 0.02 × GA). A linear relationship was detected between CL and head circumference (HC), biparietal diameter, abdominal circumference and femoral length with R2 values of 0.973, 0.970, 0.962, and 0.972, respectively. The CL/HC ratio (mean value 0.130) showed no significant correlation with GA. Clavicle lengths in the FGR group significantly decreased compared with the SGA group ( P < 0.01). This study determined a reference range of fetal CL in a Chinese population. Furthermore, the CL/HC ratio, which is independent of GA, is a novel parameter for the evaluation of the fetal clavicle.
Identifiants
pubmed: 36802413
doi: 10.1097/RUQ.0000000000000637
pii: 00013644-990000000-00034
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
129-133Informations de copyright
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
Références
Ogata S, Uhthoff HK. The early development and ossification of the human clavicle–an embryologic study. Acta Orthop. Scand . 1990;61(4):330–334.
Baumgart M, Wisniewski M, Grzonkowska M, et al. Morphometric study of the two fused primary ossification centers of the clavicle in the human fetus. Surg. Radiol. Anat . 2016;38(8):937–945.
Garzon-Alvarado DA, Gutiérrez ML, Calixto LF. A computational model of clavicle bone formation: a mechano-biochemical hypothesis. Bone . 2014;61:132–137.
Tanaka JL, Ono E, Filho EM, et al. Cleidocranial dysplasia: importance of radiographic images in diagnosis of the condition. J. Oral Sci . 2006;48(3):161–166.
Sherer DM, Sokolovski M, Dalloul M, et al. Fetal clavicle length throughout gestation: a nomogram. Ultrasound Obstet. Gynecol . 2006;27(3):306–310.
Yarkoni S, Schmidt W, Jeanty P, et al. Clavicular measurement: a new biometric parameter for fetal evaluation. J. Ultrasound Med . 1985;4(9):467–470.
Wisniewski M, Baumgart M, Grzonkowska M, et al. Quantitative anatomy of the growing clavicle in the human fetus: CT, digital image analysis, and statistical study. Surg. Radiol. Anat . 2017;39(8):827–835.
Lei T, Xie HN, Zhu Y, et al. Date-independent parameters: an innovative method to assess fetal cerebellar vermis. Cerebellum . 2015;14(3):231–239.
Salomon LJ, Alfirevic Z, Da Silva Costa F, et al. ISUOG practice guidelines: ultrasound assessment of fetal biometry and growth. Ultrasound Obstet. Gynecol . 2019;53(6):715–723.
Gordijn S, Beune I, Thilaganathan B, et al. Consensus definition of fetal growth restriction: a Delphi procedure. Ultrasound Obstet. Gynecol . 2016;48(3):333–339.
Lorenz JM, Whitaker AH, Feldman JF, et al. Indices of body and brain size at birth and at the age of 2 years: relations to cognitive outcome at the age of 16 years in low birth weight infants. J. Dev. Behav. Pediatr . 2009;30(6):535–543.
Pilu G, Falco P, Milano V, et al. Prenatal diagnosis of microcephaly assisted by vaginal sonography and power Doppler. Ultrasound Obstet. Gynecol . 1998;11(5):357–360.
Enzan H, Hara H, Izumi T, et al. Morphologic and radiological observations on the earliest bone marrow formation in human embryos and fetuses. Acta Pathol. Jpn . 1983;33(3):439–446.
Unterscheider J, O'Donoghue K, Daly S, et al. Fetal growth restriction and the risk of perinatal mortality-case studies from the multicentre PORTO study. BMC Pregnancy Childbirth . 2014;14:63.
Baschat AA. Neurodevelopment following fetal growth restriction and its relationship with antepartum parameters of placental dysfunction. Ultrasound Obstet. Gynecol . 2011;37(5):501–514.