Combined uterorelaxant effect of magnesium sulfate and terbutaline: Studies on late pregnant rat uteri in vitro and in vivo.
magnesium sulfate
pregnancy
tocolysis
uterine contractility
β2-adrenoreceptor agonists
Journal
Acta obstetricia et gynecologica Scandinavica
ISSN: 1600-0412
Titre abrégé: Acta Obstet Gynecol Scand
Pays: United States
ID NLM: 0370343
Informations de publication
Date de publication:
04 2023
04 2023
Historique:
revised:
24
01
2023
received:
19
10
2022
accepted:
01
02
2023
pubmed:
23
2
2023
medline:
15
3
2023
entrez:
22
2
2023
Statut:
ppublish
Résumé
Preterm delivery and its complications are among the biggest challenges and health risks in obstetrical practice. Several tocolytic agents are used in clinical practice, although the efficacy and side effect profiles of these drugs are not satisfying. The aim of this study was to investigate the uterus relaxant effect of the coadministration of β In the isolated organ bath studies, rhythmic contractions of 22-day- pregnant Sprague-Dawley rats were stimulated with KCl, and cumulative dose-response curves were constructed in the presence of MgSO Both MgSO The combined application of MgSO
Identifiants
pubmed: 36808376
doi: 10.1111/aogs.14532
pmc: PMC10008284
doi:
Substances chimiques
Terbutaline
N8ONU3L3PG
Magnesium Sulfate
7487-88-9
Tocolytic Agents
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
457-464Subventions
Organisme : Ministry of Innovation and Technology of Hungary
ID : TKP2021-EGA-32
Organisme : National Research, Development, and Innovation Fund
ID : TKP2021-EGA
Informations de copyright
© 2023 The Authors. Acta Obstetricia et Gynecologica Scandinavica published by John Wiley & Sons Ltd on behalf of Nordic Federation of Societies of Obstetrics and Gynecology (NFOG).
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