A Retrospective Comparison of the Efficacy of Embolization with Imipenem/Cilastatin and Microspheres in the Management of Chronic Shoulder Pain.
Chronic shoulder pain
Cilastatin
Embolization
Imipenem
Neovessels
Safety
Journal
Cardiovascular and interventional radiology
ISSN: 1432-086X
Titre abrégé: Cardiovasc Intervent Radiol
Pays: United States
ID NLM: 8003538
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
received:
21
09
2022
accepted:
31
01
2023
medline:
5
6
2023
pubmed:
25
2
2023
entrez:
24
2
2023
Statut:
ppublish
Résumé
To compare the efficacy of embolization with imipenem/cilastatin and microspheres in chronic shoulder pain. This retrospective study included 29 patients who underwent embolization for chronic shoulder pain between June 2017 and March 2022 with calibrated MSs from 100 to 250 µm or IMP/CS. The main objective was the clinical success evaluated by the Minimum Clinically Important Difference (MCID) at 3 months after the procedure, validated if the patient responded yes to 2 questions: (1) Is the pain less severe than before the procedure? (2) Are you satisfied with the procedure? The decrease in visual analogue pain scale scores and the safety of the procedure were evaluated. Embolization was achieved in all patients. In the MS group, 4/15 patients (26.7%) experienced clinical success at 3 months according to MCID versus 10/14 patients (71.4%) in the IMP/CS group (p = 0.02). The mean VAS decreases were respectively - 28.6% ± 34.6 in the MS group and - 36.8% ± 27.8 in the IMP/CS group at 1 month (p = 0.50), - 29.9% ± 29.0 and - 39.6% ± 23.0 at 3 months (p = 0.33) and - 30.6% ± 32.8 and - 46.6% ± 28.4 at 6 months after the procedure (p = 0.26). Eleven patients (73.3%) in the MS group and 3 patients (21.4%) in the IMP/CS group had complications (p = 0.01). Among them, 2/15 patients (13.3%) had transient skin ischaemia in the MS group. Embolization with IMP/CS may be more effective and safer than MSs in the management of chronic shoulder pain.
Identifiants
pubmed: 36826491
doi: 10.1007/s00270-023-03385-2
pii: 10.1007/s00270-023-03385-2
doi:
Substances chimiques
Imipenem
71OTZ9ZE0A
Cilastatin
141A6AMN38
Drug Combinations
0
Cilastatin, Imipenem Drug Combination
92309-29-0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
748-757Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2023. Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).
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