Association between insomnia and the incidence of myocardial infarction: A systematic review and meta-analysis.
STEMI
insomnia
myocardial infarction
sleep disorders
Journal
Clinical cardiology
ISSN: 1932-8737
Titre abrégé: Clin Cardiol
Pays: United States
ID NLM: 7903272
Informations de publication
Date de publication:
Apr 2023
Apr 2023
Historique:
revised:
04
12
2022
received:
16
10
2022
accepted:
28
12
2022
medline:
18
4
2023
pubmed:
26
2
2023
entrez:
25
2
2023
Statut:
ppublish
Résumé
Insomnia has been closely associated with cardiovascular disease (CVD) including myocardial infarction (MI). Our study aims to assess the eligibility of insomnia as a potential risk factor for MI. PubMed, Scopus, and Web of Science were searched using terms; such as "Insomnia" and "MI." Only observational controlled studies with data on the incidence of MI among insomniacs were included. Revman software version 5.4 was used for the analysis. Our pooled analysis showed a significant association between insomnia and the incidence of MI compared with noninsomniacs (relative risk [RR] = 1.69, 95% confidence interval [CI] = 1.41-2.02, p < .00001). Per sleep duration, we detected the highest association between ≤5 h of sleep, and MI incidence compared to 7-8 h of sleep (RR = 1.56, 95% CI = 1.41-1.73). Disorders of initiating and maintaining sleep were associated with increased MI incidence (RR = 1.13, 95% CI = 1.04-1.23, p = .003). However, subgroup analysis of nonrestorative sleep and daytime dysfunction showed an insignificant association with MI among both groups (RR = 1.06, 95% CI = 0.91-1.23, p = .46). Analysis of age, follow-up duration, sex, and comorbidities showed a significant association in insomniacs. Insomnia and ≤5 h of sleep are highly associated with increased incidence of MI; an association comparable to that of other MI risk factors and as such, it should be considered as a risk factor for MI and to be incorporated into MI prevention guidelines.
Sections du résumé
BACKGROUND
BACKGROUND
Insomnia has been closely associated with cardiovascular disease (CVD) including myocardial infarction (MI). Our study aims to assess the eligibility of insomnia as a potential risk factor for MI.
METHODS
METHODS
PubMed, Scopus, and Web of Science were searched using terms; such as "Insomnia" and "MI." Only observational controlled studies with data on the incidence of MI among insomniacs were included. Revman software version 5.4 was used for the analysis.
RESULTS
RESULTS
Our pooled analysis showed a significant association between insomnia and the incidence of MI compared with noninsomniacs (relative risk [RR] = 1.69, 95% confidence interval [CI] = 1.41-2.02, p < .00001). Per sleep duration, we detected the highest association between ≤5 h of sleep, and MI incidence compared to 7-8 h of sleep (RR = 1.56, 95% CI = 1.41-1.73). Disorders of initiating and maintaining sleep were associated with increased MI incidence (RR = 1.13, 95% CI = 1.04-1.23, p = .003). However, subgroup analysis of nonrestorative sleep and daytime dysfunction showed an insignificant association with MI among both groups (RR = 1.06, 95% CI = 0.91-1.23, p = .46). Analysis of age, follow-up duration, sex, and comorbidities showed a significant association in insomniacs.
CONCLUSION
CONCLUSIONS
Insomnia and ≤5 h of sleep are highly associated with increased incidence of MI; an association comparable to that of other MI risk factors and as such, it should be considered as a risk factor for MI and to be incorporated into MI prevention guidelines.
Identifiants
pubmed: 36841256
doi: 10.1002/clc.23984
pmc: PMC10106668
doi:
Types de publication
Meta-Analysis
Systematic Review
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
376-385Informations de copyright
© 2023 The Authors. Clinical Cardiology published by Wiley Periodicals, LLC.
Références
Neurology. 2019 Dec 3;93(23):e2110-e2120
pubmed: 31694922
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
J Clin Med. 2021 Apr 20;10(8):
pubmed: 33924190
Atherosclerosis. 2014 Feb;232(2):414-9
pubmed: 24468157
BMC Cardiovasc Disord. 2021 Oct 7;21(1):481
pubmed: 34620076
Mayo Clin Proc. 2021 Feb;96(2):332-341
pubmed: 33483147
Ann Epidemiol. 1998 Aug;8(6):384-92
pubmed: 9708874
Sleep. 2010 Jun;33(6):739-44
pubmed: 20550013
Curr Cardiol Rev. 2010 Feb;6(1):54-61
pubmed: 21286279
J Psychosom Res. 1998 Jul;45(1):21-31
pubmed: 9720852
J Sleep Res. 2012 Aug;21(4):427-33
pubmed: 22151079
Heart. 2015 Aug;101(15):1182-9
pubmed: 26041770
Eur J Prev Cardiol. 2014 Jan;21(1):57-64
pubmed: 22942213
Sci Rep. 2020 Dec 31;10(1):22456
pubmed: 33384452
Eur J Epidemiol. 2010 Sep;25(9):603-5
pubmed: 20652370
Eur J Prev Cardiol. 2017 Jul;24(10):1071-1082
pubmed: 28359160
J Am Coll Cardiol. 2019 Sep 10;74(10):1304-1314
pubmed: 31488267
Psychosom Med. 2015 Sep;77(7):743-51
pubmed: 26355726
Sleep Med Rev. 2018 Jun;39:25-36
pubmed: 28890167
Sleep. 2013 Dec 01;36(12):1963-8
pubmed: 24293772
Arch Intern Med. 2003 Jan 27;163(2):205-9
pubmed: 12546611
J Occup Environ Med. 2015 Oct;57(10):1031-8
pubmed: 26461857
Front Psychiatry. 2021 May 14;12:654719
pubmed: 34054612
Clin Cardiol. 2023 Apr;46(4):376-385
pubmed: 36841256
Sleep. 2016 Dec 01;39(12):2101-2111
pubmed: 27634805
Int J Environ Res Public Health. 2018 Jul 26;15(8):
pubmed: 30049991
Eur Heart J. 2008 Apr;29(7):932-40
pubmed: 18334475
J Epidemiol Community Health. 2006 Jan;60(1):69-73
pubmed: 16361457
Sleep. 2007 Sep;30(9):1121-7
pubmed: 17910384
Circulation. 2011 Nov 8;124(19):2073-81
pubmed: 22025601
Epidemiol Psychiatr Sci. 2019 Aug 20;29:e50
pubmed: 31426879
Sleep Med Rev. 2013 Aug;17(4):241-54
pubmed: 23419741