Is mid-gestational uterine artery Doppler still useful in a setting with routine first-trimester pre-eclampsia screening? A cohort study.


Journal

BJOG : an international journal of obstetrics and gynaecology
ISSN: 1471-0528
Titre abrégé: BJOG
Pays: England
ID NLM: 100935741

Informations de publication

Date de publication:
08 2023
Historique:
revised: 28 12 2022
received: 03 10 2022
accepted: 21 01 2023
medline: 12 7 2023
pubmed: 1 3 2023
entrez: 28 2 2023
Statut: ppublish

Résumé

To evaluate whether routine mid-gestational uterine artery Doppler (UtAD) modifies the risk for preterm pre-eclampsia after first-trimester combined pre-eclampsia screening. Retrospective cohort study. London Tertiary Hospital. A cohort of 7793 women with singleton pregnancies, first-trimester pre-eclampsia screening using the Fetal Medicine Foundation (FMF) algorithm and UtAD pulsatility index (PI) assessment at the mid-gestation ultrasound. Pregnancies were divided into four groups: high risk in both trimesters (H Small for gestational age (SGA), hypertensive disorders of pregnancy (HDP) and stillbirth. In this cohort, 600 (7.7%) and 620 (7.9%) women were designated as being at high risk in the first and second trimesters, respectively. Preterm pre-eclampsia was more prevalent in the H Pre-eclampsia risk after first-trimester FMF pre-eclampsia screening may be stratified through mid-gestational routine UtAD assessment. Pregnancy care should not be de-escalated for low mid-gestational UtAD resistance in women classified as being at high risk in the first trimester. The escalation of care may be justified in women at low risk but with high mid-gestational UtAD resistance.

Identifiants

pubmed: 36852521
doi: 10.1111/1471-0528.17441
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1128-1134

Informations de copyright

© 2023 The Authors. BJOG: An International Journal of Obstetrics and Gynaecology published by John Wiley & Sons Ltd.

Références

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Auteurs

Anna Meroni (A)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Medicine and Surgery, Obstetrics and Gynaecology Unit, Università degli Studi di Pavia, Pavia, Italy.

Margaret Mascherpa (M)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Medicine and Surgery, Obstetrics and Gynaecology Unit, Università degli Studi di Brescia, Brescia, Italy.

Monica Minopoli (M)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Medicine and Surgery, Obstetrics and Gynaecology Unit, Università degli Study di Parma, Parma, Italy.

Benjamin Lambton (B)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.

Rawan Elkalaawy (R)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.

Alexander Frick (A)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Vascular Biology Research Centre, Molecular and Clinical Sciences Research Institute, St George's, University of London, London, UK.

Basky Thilaganathan (B)

Fetal Medicine Unit, St George's University Hospitals NHS Foundation Trust, London, UK.
Department of Medicine and Surgery, Obstetrics and Gynaecology Unit, Università degli Studi di Pavia, Pavia, Italy.

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