Ferroptosis: friend or foe in cancer immunotherapy?

Immunogenic cell death cancer immunosuppression immunogenic ferroptosis

Journal

Oncoimmunology
ISSN: 2162-402X
Titre abrégé: Oncoimmunology
Pays: United States
ID NLM: 101570526

Informations de publication

Date de publication:
2023
Historique:
entrez: 6 3 2023
pubmed: 7 3 2023
medline: 8 3 2023
Statut: epublish

Résumé

Ferroptosis has gained interest due to it immunogenicity and the higher sensitivity of cancer cells to it. However, it was recently shown that ferroptosis in tumor-associated neutrophils leads to immunosuppression and negatively impacts therapy. Here, we discuss the potential implications of the two sides (friend

Identifiants

pubmed: 36875549
doi: 10.1080/2162402X.2023.2182992
pii: 2182992
pmc: PMC9980624
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2182992

Informations de copyright

© 2023 The Author(s). Published with license by Taylor & Francis Group, LLC.

Déclaration de conflit d'intérêts

Authors declare no conflict of interests.

Références

J Immunother Cancer. 2021 Dec;9(12):
pubmed: 34903554
Nature. 2022 Dec;612(7939):338-346
pubmed: 36385526
Mol Med. 2012 Dec 20;18:1360-2
pubmed: 23073660
Immunity. 2021 Apr 13;54(4):721-736.e10
pubmed: 33725478
Cell Metab. 2021 Aug 3;33(8):1701-1715.e5
pubmed: 34118189
Nat Commun. 2020 Dec 7;11(1):6299
pubmed: 33288764
Nat Commun. 2022 Jun 27;13(1):3676
pubmed: 35760796
Nat Rev Cancer. 2019 Jul;19(7):405-414
pubmed: 31101865
J Immunother Cancer. 2020 Nov;8(2):
pubmed: 33188036
Nat Immunol. 2022 Apr;23(4):487-500
pubmed: 35145297
Cell Death Differ. 2018 Mar;25(3):486-541
pubmed: 29362479
Autophagy. 2022 Sep;18(9):2036-2049
pubmed: 34964698
Cell. 2012 May 25;149(5):1060-72
pubmed: 22632970

Auteurs

Robin Demuynck (R)

Cell Death Investigation and Therapy (CDIT) Laboratory, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Cancer Research Institute Ghent, Ghent, Belgium.

Iuliia Efimova (I)

Cell Death Investigation and Therapy (CDIT) Laboratory, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Cancer Research Institute Ghent, Ghent, Belgium.

Elena Catanzaro (E)

Cell Death Investigation and Therapy (CDIT) Laboratory, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Cancer Research Institute Ghent, Ghent, Belgium.

Dmitri V Krysko (DV)

Cell Death Investigation and Therapy (CDIT) Laboratory, Department of Human Structure and Repair, Ghent University, Ghent, Belgium.
Cancer Research Institute Ghent, Ghent, Belgium.

Articles similaires

T-Lymphocytes, Regulatory Lung Neoplasms Proto-Oncogene Proteins p21(ras) Animals Humans
Humans Male Female Health Knowledge, Attitudes, Practice Middle Aged
Humans Neoplasms Male Female Middle Aged
Humans Middle Aged Female Male Surveys and Questionnaires

Classifications MeSH