Prevalence of potentially traumatic events and symptoms of depression, anxiety, hazardous alcohol use, and post-traumatic stress disorder among people with HIV initiating HIV care in Cameroon.


Journal

BMC psychiatry
ISSN: 1471-244X
Titre abrégé: BMC Psychiatry
Pays: England
ID NLM: 100968559

Informations de publication

Date de publication:
09 03 2023
Historique:
received: 11 04 2022
accepted: 22 02 2023
entrez: 9 3 2023
pubmed: 10 3 2023
medline: 14 3 2023
Statut: epublish

Résumé

This study explored the relationship between specific types of potentially traumatic events (PTEs) and symptoms of mental health disorders among people with HIV (PWH) in Cameroon. We conducted a cross-sectional study with 426 PWH in Cameroon between 2019-2020. Multivariable log binominal regression was used to estimate the association between exposure (yes/no) to six distinct types of PTE and symptoms of depression (Patient Health Questionnaire-9 score > 9), PTSD (PTSD Checklist for DSM-5 score > 30), anxiety (Generalized Anxiety Disorder-7 scale score > 9), and hazardous alcohol use (Alcohol Use Disorders Identification Test score > 7 for men; > 6 for women). A majority of study participants (96%) reported exposure to at least one PTE, with a median of 4 PTEs (interquartile range: 2-5). The most commonly reported PTEs were seeing someone seriously injured or killed (45%), family members hitting or harming one another as a child (43%), physical assault or abuse from an intimate partner (42%) and witnessing physical assault or abuse (41%). In multivariable analyses, the prevalence of PTSD symptoms was significantly higher among those who reported experiencing PTEs during childhood, violent PTEs during adulthood, and the death of a child. The prevalence of anxiety symptoms was significantly higher among those who reported experiencing both PTEs during childhood and violent PTEs during adulthood. No significant positive associations were observed between specific PTEs explored and symptoms of depression or hazardous alcohol use after adjustment. PTEs were common among this sample of PWH in Cameroon and associated with PTSD and anxiety symptoms. Research is needed to foster primary prevention of PTEs and to address the mental health sequelae of PTEs among PWH.

Sections du résumé

BACKGROUND
This study explored the relationship between specific types of potentially traumatic events (PTEs) and symptoms of mental health disorders among people with HIV (PWH) in Cameroon.
METHODS
We conducted a cross-sectional study with 426 PWH in Cameroon between 2019-2020. Multivariable log binominal regression was used to estimate the association between exposure (yes/no) to six distinct types of PTE and symptoms of depression (Patient Health Questionnaire-9 score > 9), PTSD (PTSD Checklist for DSM-5 score > 30), anxiety (Generalized Anxiety Disorder-7 scale score > 9), and hazardous alcohol use (Alcohol Use Disorders Identification Test score > 7 for men; > 6 for women).
RESULTS
A majority of study participants (96%) reported exposure to at least one PTE, with a median of 4 PTEs (interquartile range: 2-5). The most commonly reported PTEs were seeing someone seriously injured or killed (45%), family members hitting or harming one another as a child (43%), physical assault or abuse from an intimate partner (42%) and witnessing physical assault or abuse (41%). In multivariable analyses, the prevalence of PTSD symptoms was significantly higher among those who reported experiencing PTEs during childhood, violent PTEs during adulthood, and the death of a child. The prevalence of anxiety symptoms was significantly higher among those who reported experiencing both PTEs during childhood and violent PTEs during adulthood. No significant positive associations were observed between specific PTEs explored and symptoms of depression or hazardous alcohol use after adjustment.
CONCLUSIONS
PTEs were common among this sample of PWH in Cameroon and associated with PTSD and anxiety symptoms. Research is needed to foster primary prevention of PTEs and to address the mental health sequelae of PTEs among PWH.

Identifiants

pubmed: 36894918
doi: 10.1186/s12888-023-04630-1
pii: 10.1186/s12888-023-04630-1
pmc: PMC9996899
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

150

Subventions

Organisme : NICHD NIH HHS
ID : P2C HD050924
Pays : United States
Organisme : NIMHD NIH HHS
ID : T37 MD014218
Pays : United States
Organisme : NIMH NIH HHS
ID : K01 MH114721
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI096299
Pays : United States

Informations de copyright

© 2023. The Author(s).

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Auteurs

Angela M Parcesepe (AM)

Gillings School of Global Public Health, Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. angela_parcesepe@unc.edu.
University of North Carolina at Chapel Hill, Carolina Population Center, Chapel Hill, NC, USA. angela_parcesepe@unc.edu.

Lindsey M Filiatreau (LM)

Department of Psychiatry, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Peter Vanes Ebasone (PV)

Clinical Research Education Networking and Consultancy, Yaounde, Cameroon.

Anastase Dzudie (A)

Clinical Research Education Networking and Consultancy, Yaounde, Cameroon.

Brian W Pence (BW)

Department of Psychiatry, School of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

Milton Wainberg (M)

Department of Psychiatry, Columbia University and New York State Psychiatric Institute, New York, NY, USA.

Marcel Yotebieng (M)

Albert Einstein College of Medicine, Department of Medicine, Bronx, NY, USA.

Kathryn Anastos (K)

Albert Einstein College of Medicine, Departments of Medicine and Epidemiology & Population Health, Bronx, NY, USA.

Eric Pefura-Yone (E)

Jamot Hospital, Yaounde, Cameroon.

Denis Nsame (D)

Bamenda Regional Hospital, Bamenda, Cameroon.

Rogers Ajeh (R)

Clinical Research Education Networking and Consultancy, Yaounde, Cameroon.

Denis Nash (D)

Institute for Implementation Science in Population Health, City University of New York, New York, NY, USA.

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