Incidence and risk factors of postoperative nausea and vomiting following laparoscopic sleeve gastrectomy and its relationship with Helicobacter pylori: A propensity score matching analysis.
Helicobacter pylori
bariatric surgery
nausea
pain
sleeve gastrectomy
vomiting
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2023
2023
Historique:
received:
18
11
2022
accepted:
10
02
2023
entrez:
13
3
2023
pubmed:
14
3
2023
medline:
15
3
2023
Statut:
epublish
Résumé
Postoperative nausea and vomiting (PONV) are common after laparoscopic sleeve gastrectomy (LSG), affecting patient satisfaction and postoperative recovery. The purpose of this study was to investigate the incidence and severity of PONV after LSG and the relationship between Helicobacter pylori (HP) and PONV. Patients undergoing LSG in our center from June 1, 2018, to May 31, 2022, were divided into HP-positive and HP-negative groups for retrospective analysis. The independent risk factors of PONV were determined by univariate and binary logistic regression analysis using a 1:1 propensity score matching (PSM) method. A total of 656 patients was enrolled, and 193 pairs of HP-positive and negative groups were matched after PSM. Both groups of patients had similar clinical features and surgical procedures. PONV occurred in 232 patients (60.1%) after LSG, and the incidence of PONV in HP-positive patients was 61.10%. The incidence and severity of PONV were statistically similar in both groups (P=0.815). Multivariate analysis showed that the female sex (OR=1.644, P=0.042), postoperative pain (OR=2.203, P=0.001) and use of postoperative opioid (OR=2.229, P=0.000) were independent risk factors for PONV after LSG, whereas T2DM (OR=0.510, P=0.009) and OSAS (OR=0.545, P=0.008) independently reduced the incidence rate of PONV. There was no difference either in smoking (P=0.255) or alcohol drinking (P=0.801). HP infection did not affect PONV (P=0.678). The incidence of PONV following LSG was relatively high. Female sex, postoperative pain and use of postoperative opioid predicted a higher incidence of PONV. Patients with T2DM and OSAS were less likely to have PONV. There was no clear association between HP infection and PONV after LSG.
Sections du résumé
Background
Postoperative nausea and vomiting (PONV) are common after laparoscopic sleeve gastrectomy (LSG), affecting patient satisfaction and postoperative recovery. The purpose of this study was to investigate the incidence and severity of PONV after LSG and the relationship between Helicobacter pylori (HP) and PONV.
Methods
Patients undergoing LSG in our center from June 1, 2018, to May 31, 2022, were divided into HP-positive and HP-negative groups for retrospective analysis. The independent risk factors of PONV were determined by univariate and binary logistic regression analysis using a 1:1 propensity score matching (PSM) method.
Results
A total of 656 patients was enrolled, and 193 pairs of HP-positive and negative groups were matched after PSM. Both groups of patients had similar clinical features and surgical procedures. PONV occurred in 232 patients (60.1%) after LSG, and the incidence of PONV in HP-positive patients was 61.10%. The incidence and severity of PONV were statistically similar in both groups (P=0.815). Multivariate analysis showed that the female sex (OR=1.644, P=0.042), postoperative pain (OR=2.203, P=0.001) and use of postoperative opioid (OR=2.229, P=0.000) were independent risk factors for PONV after LSG, whereas T2DM (OR=0.510, P=0.009) and OSAS (OR=0.545, P=0.008) independently reduced the incidence rate of PONV. There was no difference either in smoking (P=0.255) or alcohol drinking (P=0.801). HP infection did not affect PONV (P=0.678).
Conclusions
The incidence of PONV following LSG was relatively high. Female sex, postoperative pain and use of postoperative opioid predicted a higher incidence of PONV. Patients with T2DM and OSAS were less likely to have PONV. There was no clear association between HP infection and PONV after LSG.
Identifiants
pubmed: 36909334
doi: 10.3389/fendo.2023.1102017
pmc: PMC9992875
doi:
Substances chimiques
Analgesics, Opioid
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1102017Informations de copyright
Copyright © 2023 Song, Zhu, Dong, Wang, Xiao and Yang.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Hepatogastroenterology. 2008 May-Jun;55(84):883-6
pubmed: 18705288
Anesth Analg. 1994 Jan;78(1):7-16
pubmed: 8267183
Obes Surg. 2010 Jul;20(7):876-80
pubmed: 18925384
Anesth Analg. 2014 Jan;118(1):85-113
pubmed: 24356162
Obes Surg. 2019 May;29(5):1614-1623
pubmed: 30734195
AANA J. 2020 Apr;88(2):142-147
pubmed: 32234206
Obes Surg. 2008 Sep;18(9):1083-8
pubmed: 18535864
N Engl J Med. 2017 Jul 6;377(1):13-27
pubmed: 28604169
ScientificWorldJournal. 2014;2014:487215
pubmed: 25126598
PLoS One. 2013 Jul 30;8(7):e65174
pubmed: 23935815
Anaesthesia. 2000 Dec;55(12):1164-7
pubmed: 11121924
J Am Coll Cardiol. 2013 Aug 13;62(7):569-76
pubmed: 23770180
Dtsch Arztebl Int. 2018 Jun 22;115(25):429-436
pubmed: 29999489
Anesth Essays Res. 2016 Sep-Dec;10(3):388-396
pubmed: 27746521
Br J Anaesth. 2012 Nov;109(5):742-53
pubmed: 23035051
J Korean Assoc Oral Maxillofac Surg. 2020 Apr 30;46(2):116-124
pubmed: 32364351
Obes Surg. 2020 Dec;30(12):5071-5085
pubmed: 32981000
Br J Anaesth. 2012 Mar;108(3):423-9
pubmed: 22290456
Eur J Pharmacol. 2014 Jan 5;722:55-66
pubmed: 24495419
J Am Coll Cardiol. 2017 Oct 17;70(16):2022-2035
pubmed: 29025560
Nat Rev Gastroenterol Hepatol. 2017 Mar;14(3):160-169
pubmed: 27899816
J Clin Anesth. 2012 May;24(3):185-92
pubmed: 22459340
Helicobacter. 2018 Feb;23(1):
pubmed: 29178407
Cochrane Database Syst Rev. 2020 Oct 19;10:CD012859
pubmed: 33075160
N Engl J Med. 2004 Jun 10;350(24):2441-51
pubmed: 15190136
Adv Ther. 2000 May-Jun;17(3):152-8
pubmed: 11183452
Auton Neurosci. 2017 Jan;202:5-17
pubmed: 27450627
Curr Opin Anaesthesiol. 2016 Dec;29(6):668-673
pubmed: 27748668
N Engl J Med. 2016 Aug 25;375(8):794-8
pubmed: 27557308
Acta Anaesthesiol Scand. 2010 Mar;54(3):321-7
pubmed: 19860750
Eur J Anaesthesiol. 2016 Dec;33(12):898-905
pubmed: 26866433
JAMA. 2020 Sep 1;324(9):879-887
pubmed: 32870301
Eur Arch Paediatr Dent. 2015 Feb;16(1):35-41
pubmed: 25260983
Anesth Analg. 2020 Aug;131(2):411-448
pubmed: 32467512
Asian J Surg. 2018 Jul;41(4):301-306
pubmed: 28372932
Obes Surg. 2018 Feb;28(2):313-322
pubmed: 28822052
Clin Liver Dis. 2012 Nov;16(4):667-85
pubmed: 23101976
Am J Drug Alcohol Abuse. 2018;44(6):578-586
pubmed: 29723083
Am J Obstet Gynecol. 2017 May;216(5):512.e1-512.e9
pubmed: 28188774
Acta Anaesthesiol Scand. 2017 May;61(5):471-479
pubmed: 28374473
Anaesth Intensive Care. 2015 Jul;43(4):473-8
pubmed: 26099759
Best Pract Res Clin Anaesthesiol. 2018 Jun;32(2):137-148
pubmed: 30322455
J Gastroenterol. 2011 Jun;46(6):769-78
pubmed: 21302121
Best Pract Res Clin Anaesthesiol. 2020 Dec;34(4):667-679
pubmed: 33288117
Surg Endosc. 2022 Oct;36(10):7717-7721
pubmed: 35175414
Front Physiol. 2020 Jun 24;11:575
pubmed: 32676034
Surg Obes Relat Dis. 2020 Oct;16(10):1505-1513
pubmed: 32665115
Obes Surg. 2022 Mar;32(3):819-828
pubmed: 35088249
Obes Surg. 2016 May;26(5):1048-56
pubmed: 26220241
Joint Bone Spine. 2011 Mar;78(2):150-5
pubmed: 20580591
Helicobacter. 2005 Oct;10(5):443-4
pubmed: 16181355
Lancet. 2011 Mar 26;377(9771):1085-95
pubmed: 21397319
Br J Anaesth. 2002 May;88(5):659-68
pubmed: 12067003
Joint Bone Spine. 2012 May;79(3):291-7
pubmed: 21803633
PLoS One. 2017 Mar 16;12(3):e0171275
pubmed: 28301483
Surg Obes Relat Dis. 2017 May;13(5):774-778
pubmed: 28256393
Surg Endosc. 2020 Jul;34(7):3085-3091
pubmed: 31388805
Wideochir Inne Tech Maloinwazyjne. 2019 Jan;14(1):90-95
pubmed: 30766634
J Pain. 2019 Mar;20(3):245-263
pubmed: 30099210