Supramolecular nanoprodrug based on a chloride channel blocker and glycosylated pillar[5]arenes for targeted chemoresistance cancer therapy.

Humans Chlorides Drug Resistance, Neoplasm Prodrugs / pharmacology Hep G2 Cells Neoplasms / drug therapy

Journal

Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838

Informations de publication

Date de publication:
23 Mar 2023
Historique:
pubmed: 14 3 2023
medline: 25 3 2023
entrez: 13 3 2023
Statut: epublish

Résumé

A supramolecular nanoprodrug (DOX@GP5⊃Pro-NFA) was constructed based on the host-guest complexation of chloride channel blocker prodrug (Pro-NFA) and glycosylated pillar[5]arene (GP5), which could target tumor cells

Identifiants

DOI: 10.1039/d3cc00233k PMID: 36912355
pubmed: 36912355
doi: 10.1039/d3cc00233k
doi:

Substances chimiques

Chlorides 0
Prodrugs 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3779-3782

Auteurs

Ke Yang (K)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.

Ke Ma (K)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.

Manman Yang (M)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.

Yinghua Lv (Y)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.
ORCID: 0000-0001-8241-399X

Yuxin Pei (Y)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.
ORCID: 0000-0002-6316-9626

Zhichao Pei (Z)

Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling 712100, P. R. China. peizc@nwafu.edu.cn.
ORCID: 0000-0003-4334-0999

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Supramolecular nanoprodrug based on a chloride...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Anions › Chlorures › Supramolecular nanoprodrug based on a chloride...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance aux médicaments antinéoplasiques › Supramolecular nanoprodrug based on a chloride...
questionsmedicales.fr › Préparations pharmaceutiques › Promédicaments › Supramolecular nanoprodrug based on a chloride...
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Cellules HepG2 › Supramolecular nanoprodrug based on a chloride...
questionsmedicales.fr › Tumeurs › Supramolecular nanoprodrug based on a chloride...