On-site construction of a point-of-care low-field MRI system in Africa.
Accessibility
halbach magnets
low field MRI
open-source spectrometer
point-of-care MRI
sustainable design
Journal
NMR in biomedicine
ISSN: 1099-1492
Titre abrégé: NMR Biomed
Pays: England
ID NLM: 8915233
Informations de publication
Date de publication:
07 2023
07 2023
Historique:
revised:
14
02
2023
received:
07
11
2022
accepted:
05
03
2023
pmc-release:
01
07
2024
medline:
15
6
2023
pubmed:
14
3
2023
entrez:
13
3
2023
Statut:
ppublish
Résumé
To describe the construction and testing of a portable point-of-care low-field MRI system on site in Africa. All of the components to assemble a 50 mT Halbach magnet-based system, together with the necessary tools, were air-freighted from the Netherlands to Uganda. The construction steps included individual magnet sorting, filling of each ring of the magnet assembly, fine-tuning the inter-ring separations of the 23-ring magnet assembly, gradient coil construction, integration of gradient coils and magnet assembly, construction of the portable aluminum trolley and finally testing of the entire system with an open source MR spectrometer. With four instructors and six untrained personnel, the complete project from delivery to first image took approximately 11 days. An important step in translating scientific developments in the western world from high-income industrialized countries to low- and middle-income countries (LMICs) is to produce technology that can be assembled and ultimately constructed locally. Local assembly and construction are associated with skill development, low costs and jobs. Point-of-care systems have a large potential to increase the accessibility and sustainability of MRI in LMICs, and this work demonstrates that technology and knowledge transfer can be performed relatively seamlessly.
Identifiants
pubmed: 36914258
doi: 10.1002/nbm.4917
pmc: PMC10330026
mid: NIHMS1886710
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e4917Subventions
Organisme : NICHD NIH HHS
ID : R01 HD085853
Pays : United States
Informations de copyright
© 2023 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.
Références
Pan Afr Med J. 2018 Jul 31;30:240
pubmed: 30574259
Nat Commun. 2021 Dec 14;12(1):7238
pubmed: 34907181
J Neurosurg. 2018 Apr 1;:1-15
pubmed: 29701543
NMR Biomed. 2023 Mar;36(3):e4846
pubmed: 36259628
Magn Reson Med. 2017 Apr;77(4):1544-1552
pubmed: 27271292
J Magn Reson Imaging. 2019 Jun;49(7):e65-e77
pubmed: 30637891
Magn Reson Med. 2022 Feb;87(2):614-628
pubmed: 34480778
MAGMA. 2018 Oct;31(5):665-676
pubmed: 29644479
Nat Biomed Eng. 2021 Mar;5(3):229-239
pubmed: 33230306
Sci Rep. 2017 Oct 18;7(1):13452
pubmed: 29044156
Magn Reson Imaging. 2018 Oct;52:9-15
pubmed: 29540330
Magn Reson Med. 2021 Jan;85(1):495-505
pubmed: 32627235
J Magn Reson. 2019 Oct;307:106578
pubmed: 31470234
Sci Rep. 2022 Jul 30;12(1):13147
pubmed: 35907975
NMR Biomed. 2023 Jan;36(1):e4825
pubmed: 36097704