On-site construction of a point-of-care low-field MRI system in Africa.

Accessibility halbach magnets low field MRI open-source spectrometer point-of-care MRI sustainable design

Journal

NMR in biomedicine
ISSN: 1099-1492
Titre abrégé: NMR Biomed
Pays: England
ID NLM: 8915233

Informations de publication

Date de publication:
07 2023
Historique:
revised: 14 02 2023
received: 07 11 2022
accepted: 05 03 2023
pmc-release: 01 07 2024
medline: 15 6 2023
pubmed: 14 3 2023
entrez: 13 3 2023
Statut: ppublish

Résumé

To describe the construction and testing of a portable point-of-care low-field MRI system on site in Africa. All of the components to assemble a 50 mT Halbach magnet-based system, together with the necessary tools, were air-freighted from the Netherlands to Uganda. The construction steps included individual magnet sorting, filling of each ring of the magnet assembly, fine-tuning the inter-ring separations of the 23-ring magnet assembly, gradient coil construction, integration of gradient coils and magnet assembly, construction of the portable aluminum trolley and finally testing of the entire system with an open source MR spectrometer. With four instructors and six untrained personnel, the complete project from delivery to first image took approximately 11 days. An important step in translating scientific developments in the western world from high-income industrialized countries to low- and middle-income countries (LMICs) is to produce technology that can be assembled and ultimately constructed locally. Local assembly and construction are associated with skill development, low costs and jobs. Point-of-care systems have a large potential to increase the accessibility and sustainability of MRI in LMICs, and this work demonstrates that technology and knowledge transfer can be performed relatively seamlessly.

Identifiants

pubmed: 36914258
doi: 10.1002/nbm.4917
pmc: PMC10330026
mid: NIHMS1886710
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e4917

Subventions

Organisme : NICHD NIH HHS
ID : R01 HD085853
Pays : United States

Informations de copyright

© 2023 The Authors. NMR in Biomedicine published by John Wiley & Sons Ltd.

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Auteurs

Johnes Obungoloch (J)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Ivan Muhumuza (I)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Wouter Teeuwisse (W)

Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Joshua Harper (J)

Universidad Paraguayo Alemana, San Lorenzo, Paraguay.

Ivan Etoku (I)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Robert Asiimwe (R)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Patricia Tusiime (P)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

George Gombya (G)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Chris Mugume (C)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Mary Hellen Namutebi (MH)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Mary Anthony Nassejje (MA)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Maureen Nayebare (M)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Joseph Mark Kavuma (JM)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Benedicto Bukyana (B)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Faith Natukunda (F)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Patience Ninsiima (P)

Department of Biomedical Engineering, Mbarara University of Science and Technology, Mbarara, Uganda.

Abraham Muwanguzi (A)

Ugandan National Planning Authority, Kampala, Uganda.

Phillip Omadi (P)

Ugandan National Planning Authority, Kampala, Uganda.

Martin van Gijzen (M)

Delft Institute of Applied Mathematics, Technical University of Delft, Delft, The Netherlands.

Steven J Schiff (SJ)

Department of Neurosurgery, Yale University, New Haven, Connecticut, USA.

Andrew Webb (A)

Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

Tom O'Reilly (T)

Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands.

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