Cell biology: Kinetochores nucleate their own microtubules.


Journal

Current biology : CB
ISSN: 1879-0445
Titre abrégé: Curr Biol
Pays: England
ID NLM: 9107782

Informations de publication

Date de publication:
13 03 2023
Historique:
entrez: 14 3 2023
pubmed: 15 3 2023
medline: 17 3 2023
Statut: ppublish

Résumé

The origin of microtubules that tether the chromosomes' kinetochores to spindle poles has remained a mystery for several decades. A new study identifies the 'fibrous corona' as an autonomous microtubule nucleation site, and reveals the molecular cascade responsible for this process.

Identifiants

pubmed: 36917941
pii: S0960-9822(23)00083-0
doi: 10.1016/j.cub.2023.01.049
pii:
doi:

Types de publication

Journal Article Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

R187-R190

Commentaires et corrections

Type : CommentOn

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of interests The authors declare no competing interests.

Auteurs

Fioranna Renda (F)

Wadsworth Center, New York State Department of Health, Albany, NY, USA. Electronic address: fioranna.renda@health.ny.gov.

Alexey Khodjakov (A)

Wadsworth Center, New York State Department of Health, Albany, NY, USA. Electronic address: alexey.khodjakov@health.ny.gov.

Articles similaires

Regulation of minimal spindle midzone organization by mitotic kinases.

Wei Ming Lim, Wei-Xiang Chew, Arianna Esposito Verza et al.
1.00
Spindle Apparatus Phosphorylation Humans CDC2 Protein Kinase Protein Serine-Threonine Kinases

Kinetochore dynein is sufficient to biorient chromosomes and remodel the outer kinetochore.

Bram Prevo, Dhanya K Cheerambathur, William C Earnshaw et al.
1.00
Kinetochores Caenorhabditis elegans Animals Caenorhabditis elegans Proteins Microtubules
Animals Caenorhabditis elegans Cell Nucleus Embryo, Nonmammalian Microtubules
Arabidopsis Trichomes Microtubules Arabidopsis Proteins Morphogenesis

Classifications MeSH