Depression mediates the relationship between alexithymia and obesity in the Northern Finland Birth Cohort 1966 (NFBC1966).

Adiposity Alexithymia Body mass index Depression Depressive symptoms Mediation Obesity Waist-hip ratio

Journal

Journal of affective disorders
ISSN: 1573-2517
Titre abrégé: J Affect Disord
Pays: Netherlands
ID NLM: 7906073

Informations de publication

Date de publication:
15 06 2023
Historique:
received: 04 11 2022
revised: 08 03 2023
accepted: 11 03 2023
medline: 14 4 2023
pubmed: 19 3 2023
entrez: 18 3 2023
Statut: ppublish

Résumé

The fact that a complex relationship exists between alexithymia and body mass index (BMI) is well established, but the underlying mechanisms remain poorly understood. Here, we explore the relationship between alexithymia and depressive symptoms in relation to adiposity measures, including the direct and indirect effect of alexithymia and depressive symptoms on obesity over a 15-year time-period, in the Northern Finland Birth Cohort 1966 (NFBC1966). The study included individuals from the Northern Finland Birth Cohort 1966 (NFBC1966) who had available data for adiposity measures (body mass index and waist-to-hip ratio), alexithymia (measured by the 20-Item Toronto Alexithymia Scale: TAS-20), depressive symptoms (measured by the 13-item depression subscale of Hopkins Symptom Checklist: HSCL-13) at age of 31 years (n = 4773) and 46 years (n = 4431). Pearson's (r) correlation, and multiple linear regression were used to investigate the relationships between alexithymia, depressive symptoms, and adiposity measures. The potential mediating role of depressive symptoms was examined via Hayes' procedure (PROCESS). Positive correlations were confirmed between adiposity measures (BMI and WHR) and the TAS-20 score (and its subscale), but not between obesity and HSCL-13 score. The strongest correlation was between the DIF (difficulty identifying feelings) subscale of the TAS-20 and HSCL-13 at both time points (31 y: r Other psychological and environmental factors such as interoception, dietary intake and physical activities may also play a role as a potential mediating factor in alexithymia-obesity relationship. Our findings provide additional insights of theoretical framework of depressive symptoms mediation effect in the relationship between alexithymia and obesity. Alexithymia and depression should, therefore, be considered in the design of future clinical obesity research.

Sections du résumé

BACKGROUND
The fact that a complex relationship exists between alexithymia and body mass index (BMI) is well established, but the underlying mechanisms remain poorly understood. Here, we explore the relationship between alexithymia and depressive symptoms in relation to adiposity measures, including the direct and indirect effect of alexithymia and depressive symptoms on obesity over a 15-year time-period, in the Northern Finland Birth Cohort 1966 (NFBC1966).
METHODS
The study included individuals from the Northern Finland Birth Cohort 1966 (NFBC1966) who had available data for adiposity measures (body mass index and waist-to-hip ratio), alexithymia (measured by the 20-Item Toronto Alexithymia Scale: TAS-20), depressive symptoms (measured by the 13-item depression subscale of Hopkins Symptom Checklist: HSCL-13) at age of 31 years (n = 4773) and 46 years (n = 4431). Pearson's (r) correlation, and multiple linear regression were used to investigate the relationships between alexithymia, depressive symptoms, and adiposity measures. The potential mediating role of depressive symptoms was examined via Hayes' procedure (PROCESS).
RESULTS
Positive correlations were confirmed between adiposity measures (BMI and WHR) and the TAS-20 score (and its subscale), but not between obesity and HSCL-13 score. The strongest correlation was between the DIF (difficulty identifying feelings) subscale of the TAS-20 and HSCL-13 at both time points (31 y: r
LIMITATIONS
Other psychological and environmental factors such as interoception, dietary intake and physical activities may also play a role as a potential mediating factor in alexithymia-obesity relationship.
CONCLUSIONS
Our findings provide additional insights of theoretical framework of depressive symptoms mediation effect in the relationship between alexithymia and obesity. Alexithymia and depression should, therefore, be considered in the design of future clinical obesity research.

Identifiants

pubmed: 36933669
pii: S0165-0327(23)00361-0
doi: 10.1016/j.jad.2023.03.026
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-7

Informations de copyright

Copyright © 2023. Published by Elsevier B.V.

Déclaration de conflit d'intérêts

Conflict of interest All authors declare that they have no competing interests.

Auteurs

Nurul Hanis Ramzi (NH)

Institute for Research, Development and Innovation (IRDI), International Medical University, Kuala Lumpur, Malaysia; Department of Metabolism, Digestion and Reproduction, Division of Diabetes, Endocrinology, and Metabolism, Faculty of Medicine, Imperial College London, United Kingdom; Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, United Kingdom. Electronic address: nurulhanis@imu.edu.my.

Juha Auvinen (J)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.

Juha Veijola (J)

Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland; Department of Psychiatry, University Hospital of Oulu, Oulu, Finland; Research Unit of Clinical Neuroscience, University of Oulu, Oulu, Finland.

Jouko Miettunen (J)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.

Leena Ala-Mursula (L)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.

Sylvain Sebert (S)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland.

Sirkka Keinänen-Kiukaanniemi (S)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.

Rauli Svento (R)

Department of Economics, Oulu Business School, University of Oulu, Oulu, Finland.

Jari Jokelainen (J)

Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland.

Fotios Drenos (F)

Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, United Kingdom.

Terence M Dovey (TM)

Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, United Kingdom.

Marjo-Riitta Järvelin (MR)

Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, United Kingdom; Research Unit of Population Health, Faculty of Medicine, University of Oulu, Oulu, Finland; Biocenter Oulu, University of Oulu, Finland; Unit of Primary Health Care and Medical Research Center, Oulu University Hospital, Oulu, Finland; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London, United Kingdom.

Alexandra I F Blakemore (AIF)

Department of Metabolism, Digestion and Reproduction, Division of Diabetes, Endocrinology, and Metabolism, Faculty of Medicine, Imperial College London, United Kingdom; Department of Life Sciences, College of Health, Medicine and Life Sciences, Brunel University London, United Kingdom.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH