Multimodal evaluation of locoregional anaesthesia efficacy on postoperative pain after robotic pulmonary lobectomy for NSCLC: a pilot study.


Journal

Journal of robotic surgery
ISSN: 1863-2491
Titre abrégé: J Robot Surg
Pays: England
ID NLM: 101300401

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 17 02 2023
accepted: 18 03 2023
medline: 28 7 2023
pubmed: 27 3 2023
entrez: 26 3 2023
Statut: ppublish

Résumé

The primary objectives of the study were to analyse the robotic approach and ultrasound-guided paravertebral block compared to thoracoscopic intercostal nerve block after robotic pulmonary lobectomy on postoperative pain and opioids use. The secondary objectives were to analyse and compare patients' necessity of additional antalgic drugs and patients' performance during respiratory therapy, following robotic surgery and in the two groups. Consecutively, 52 patients undergoing robotic pulmonary lobectomies were treated either with ropivacaine-based intercostal nerve block or paravertebral block from February 2022 to October 2022. When necessary, morphine was administered at day 1. Acetaminophen was administered as an additional antalgic drug on demand up to 3 g per day. Pain was measured 1 h after the end of the surgical procedure and daily through the pain numeric rating scale (NRS). Morphine administration rate and per day and total additional administrations of acetaminophen were recorded. Pain and opioids administration was measured 1 month after the procedure. Data were analysed in the overall population and in the intercostal nerve block group VS paravertebral block group. Overall, 34.6% of the patients required morphine administration and 51.7% of the patients required at least daily acetaminophen administration up to discharge. At 1 month postoperatively, four patients presented with chronic pain and one still was under opioid medication. At intergroup analysis, the paravertebral block group demonstrated lower NRS at fixed time points (p < 0.0001) and lower morphine consumption (45.7%VS11.8%; p = 0.02). Acetaminophen rescue administration at fixed time points was lower in the paravertebral block group (p < 0.0001) and mobility and dynamic pain resulted in better results (p = 0.03; p = 0.04). At 1 month, no differences were found between study groups. Similarly to other minimally invasive techniques, postoperative pain may arise after robotic pulmonary lobectomy. Paravertebral bloc can help to reduce postoperative pain as well as morphine and antalgic drugs administration and improve early mobilization.

Identifiants

pubmed: 36967424
doi: 10.1007/s11701-023-01578-y
pii: 10.1007/s11701-023-01578-y
doi:

Substances chimiques

Analgesics, Opioid 0
Acetaminophen 362O9ITL9D
Morphine 76I7G6D29C

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1705-1713

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.

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Auteurs

Riccardo Tajè (R)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

Filippo Tommaso Gallina (FT)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy. filippogallina92@gmail.com.

Daniele Forcella (D)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

Gabriele Alessandrini (G)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

Maria Papale (M)

Department of Respiratory Physiology, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Federica Sardellitti (F)

Anesthesiology and Intensive Care Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Federico Pierconti (F)

Anesthesiology and Intensive Care Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Cecilia Coccia (C)

Anesthesiology and Intensive Care Unit, IRCCS Regina Elena National Cancer Institute, Rome, Italy.

Vincenzo Ambrogi (V)

Thoracic Surgery Department, Tor Vergata University Polyclinic, 00133, Rome, Italy.

Francesco Facciolo (F)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

Enrico Melis (E)

Thoracic Surgery Unit, IRCCS Regina Elena National Cancer Institute, Via Elio Chianesi 53, 00144, Rome, Italy.

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