Anodal Contralesional tDCS Enhances CST Excitability Bilaterally in an Adolescent with Hemiparetic Cerebral Palsy: A Brief Report.


Journal

Developmental neurorehabilitation
ISSN: 1751-8431
Titre abrégé: Dev Neurorehabil
Pays: England
ID NLM: 101304394

Informations de publication

Date de publication:
Apr 2023
Historique:
pmc-release: 01 04 2024
medline: 11 4 2023
pubmed: 28 3 2023
entrez: 27 3 2023
Statut: ppublish

Résumé

Hemiparetic cerebral palsy (HCP), weakness on one side of the body typically caused by perinatal stroke, is characterized by lifelong motor impairments related to alterations in the corticospinal tract (CST). CST reorganization could be a useful biomarker to guide applications of neuromodulatory interventions, such as transcranial direct current stimulation (tDCS), to improve the effectiveness of rehabilitation therapies. We evaluated an adolescent with HCP and CST reorganization who demonstrated persistent heightened CST excitability in both upper limbs following anodal contralesional tDCS. The results support further investigation of targeted tDCS as an adjuvant therapy to traditional neurorehabilitation for upper limb function.

Identifiants

pubmed: 36967533
doi: 10.1080/17518423.2023.2193626
pmc: PMC10228174
mid: NIHMS1885316
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

216-221

Subventions

Organisme : NICHD NIH HHS
ID : P2C HD086844
Pays : United States
Organisme : NINDS NIH HHS
ID : P30 NS076408
Pays : United States
Organisme : NIBIB NIH HHS
ID : P41 EB027061
Pays : United States
Organisme : NIH HHS
ID : S10 OD017974
Pays : United States

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Auteurs

Rodrigo G Delatorre (RG)

Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.

Ellen N Sutter (EN)

Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, USA.

Samuel T Nemanich (ST)

Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, USA.
Department of Occupational Therapy, Marquette University, Milwaukee, WI, USA.

Linda E Krach (LE)

Department of Neurology, Gillette Children's Specialty Healthcare, Saint Paul, MN, USA.

Gregg Meekins (G)

Department of Neurology, University of Minnesota, Minneapolis, MN, USA.

Timothy Feyma (T)

Department of Neurology, Gillette Children's Specialty Healthcare, Saint Paul, MN, USA.

Bernadette T Gillick (BT)

Waisman Center, University of Wisconsin-Madison, Madison, WI, USA.
Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, USA.
Department of Pediatrics, University of Wisconsin-Madison, Madison, WI, USA.

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Classifications MeSH