ChAdOx1 nCoV-19 vaccination generates spike-specific CD8


Journal

Immunology and cell biology
ISSN: 1440-1711
Titre abrégé: Immunol Cell Biol
Pays: United States
ID NLM: 8706300

Informations de publication

Date de publication:
Jul 2023
Historique:
revised: 22 03 2023
received: 20 02 2023
accepted: 27 03 2023
medline: 3 7 2023
pubmed: 29 3 2023
entrez: 28 3 2023
Statut: ppublish

Résumé

Effective vaccines have reduced the morbidity and mortality caused by severe acute respiratory syndrome coronavirus-2 infection; however, the elderly remain the most at risk. Understanding how vaccines generate protective immunity and how these mechanisms change with age is key for informing future vaccine design. Cytotoxic CD8

Identifiants

pubmed: 36975169
doi: 10.1111/imcb.12645
doi:

Substances chimiques

ChAdOx1 nCoV-19 B5S3K2V0G8
Antibodies, Viral 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

479-488

Subventions

Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/B/000C0428
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/00007031
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/W005611/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BB/T008784/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/B/000C0433
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 109407
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/I/COV07001
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/W016303/1
Pays : United Kingdom
Organisme : Biotechnology and Biological Sciences Research Council
ID : BBS/E/B/000C0427
Pays : United Kingdom

Informations de copyright

© 2023 The Authors. Immunology & Cell Biology published by John Wiley & Sons Australia, Ltd on behalf of the Australian and New Zealand Society for Immunology, Inc.

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Auteurs

William S Foster (WS)

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge, UK.

Joseph Newman (J)

The Pirbright Institute, Pirbright, Woking, UK.

Nazia Thakur (N)

The Pirbright Institute, Pirbright, Woking, UK.
The Jenner Institute, University of Oxford, Oxford, UK.

Alexandra J Spencer (AJ)

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge, UK.
Oxford Vaccine Group, Medical Sciences Division, Department of Paediatrics, University of Oxford and Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Sophie Davies (S)

The Jenner Institute, University of Oxford, Oxford, UK.

Danielle Woods (D)

Oxford Vaccine Group, Medical Sciences Division, Department of Paediatrics, University of Oxford and Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, UK.

Leila Godfrey (L)

The Jenner Institute, University of Oxford, Oxford, UK.

Sarah H Ross (SH)

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge, UK.

Hayley J Sharpe (HJ)

Signalling Programme, Babraham Institute, Babraham Research Campus, Cambridge, UK.

Arianne C Richard (AC)

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge, UK.

Dalan Bailey (D)

The Pirbright Institute, Pirbright, Woking, UK.

Teresa Lambe (T)

The Jenner Institute, University of Oxford, Oxford, UK.

Michelle A Linterman (MA)

Lymphocyte Signalling and Development, Babraham Institute, Babraham Research Campus, Cambridge, UK.

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