T

Humans Immunotherapy, Adoptive / methods Neoplasms T-Lymphocytes Cytokines / metabolism Stem Cells / metabolism Receptors, Antigen, T-Cell / metabolism

Journal

Science translational medicine
ISSN: 1946-6242
Titre abrégé: Sci Transl Med
Pays: United States
ID NLM: 101505086

Informations de publication

Date de publication:
05 04 2023
Historique:
medline: 7 4 2023
entrez: 5 4 2023
pubmed: 6 4 2023
Statut: ppublish

Résumé

Patients who receive chimeric antigen receptor (CAR)-T cells that are enriched in memory T cells exhibit better disease control as a result of increased expansion and persistence of the CAR-T cells. Human memory T cells include stem-like CD8

Identifiants

DOI: 10.1126/scitranslmed.abk1900 PMID: 37018415
pubmed: 37018415
doi: 10.1126/scitranslmed.abk1900
doi:

Substances chimiques

Cytokines 0
Receptors, Antigen, T-Cell 0

Banques de données

ClinicalTrials.gov
['NCT03851146']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabk1900

Auteurs

Deborah Meyran (D)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Université de Paris, Inserm, U976 HIPI Unit, Institut de Recherche Saint-Louis, Paris F-75010, France.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0003-2723-8185

Joe Jiang Zhu (JJ)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0003-4416-7040

Jeanne Butler (J)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

Daniela Tantalo (D)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
ORCID: 0000-0002-5892-8990

Sean MacDonald (S)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

Thu Ngoc Nguyen (TN)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
ORCID: 0000-0003-3755-3170

Minyu Wang (M)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-1051-5855

Niko Thio (N)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
ORCID: 0000-0002-3089-0871

Criselle D'Souza (C)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0003-2257-6388

Vicky Mengfei Qin (VM)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-3336-1860

Clare Slaney (C)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-6986-6115

Aaron Harrison (A)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

Kevin Sek (K)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0003-4634-7600

Pasquale Petrone (P)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

Kevin Thia (K)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
ORCID: 0000-0002-4172-5628

Lauren Giuffrida (L)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.

Andrew M Scott (AM)

Tumor Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, VIC 3084, Australia.
School of Cancer Medicine, La Trobe University, Melbourne, VIC 3086, Australia.
ORCID: 0000-0002-6656-295X

Rachael L Terry (RL)

Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW 1466, Australia.

Ben Tran (B)

Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
ORCID: 0000-0001-9124-354X

Jayesh Desai (J)

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
ORCID: 0000-0003-4246-9344

H Miles Prince (HM)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
ORCID: 0000-0002-0058-2448

Simon J Harrison (SJ)

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
ORCID: 0000-0003-4555-6582

Paul A Beavis (PA)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-2116-013X

Michael H Kershaw (MH)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-2697-487X

Ben Solomon (B)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
Division of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
ORCID: 0000-0003-3059-5730

Paul G Ekert (PG)

Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW 1466, Australia.
School of Women's and Children's Health, UNSW Sydney, Sydney, NSW 1466, Australia.
Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW 2031, Australia.
Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, VIC 3052, Australia.
ORCID: 0000-0002-2976-8617

Joseph A Trapani (JA)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0003-0983-1532

Phillip K Darcy (PK)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-5303-9561

Paul J Neeson (PJ)

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne 3000, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne 3010, Australia.
ORCID: 0000-0002-2729-5887

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › T
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Immunisation passive › Transfert adoptif › Immunothérapie adoptive › T
questionsmedicales.fr › Tumeurs › T
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Lymphocytes T › T
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › T
questionsmedicales.fr › Cellules › Cellules souches › T
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Récepteurs de surface cellulaire › Récepteurs immunologiques › Récepteurs aux antigènes › Récepteurs aux antigènes des cellules T › T