Kevin Sek

Affiliations

Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia.

Publications (17)

Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity.

Nature immunology

Avec: Junyun Lai , Sherly Mardiana , Imran G House , Kevin Sek , Melissa A Henderson , Lauren Giuffrida , Amanda X Y Chen , Kirsten L Todd , Emma V Petley , Jack D Chan , Emma M Carrington , Andrew M Lew , Benjamin J Solomon , Joseph A Trapani , Katherine Kedzierska , Maximilien Evrard , Stephin J Vervoort , Jason Waithman , Phillip K Darcy , Paul A Beavis

CRISPR/Cas9 mediated deletion of the adenosine A2A receptor enhances CAR T cell efficacy.

Nature communications

Avec: Lauren Giuffrida , Kevin Sek , Melissa A Henderson , Junyun Lai , Amanda X Y Chen , Deborah Meyran , Kirsten L Todd , Emma V Petley , Sherly Mardiana , Christina Mølck , Gregory D Stewart , Benjamin J Solomon , Ian A Parish , Paul J Neeson , Simon J Harrison , Lev M Kats , Imran G House , Phillip K Darcy , Paul A Beavis

Intermittently scanned continuous glucose monitoring provides no benefit over structured self-monitoring of blood glucose in type 2 diabetes not on prandial insulin, in the context of diabetes self-management education: GLucose monitoring programme SingaporE (GLiMPSE).

Diabetes research and clinical practice

Avec: Suresh Rama Chandran , Nabilah Rahman , Mihir Gandhi , Ngiap Chuan Tan , Ian K Y Phoon , Darren E J Seah , Ming Hann Cheah , Kathleen Sek , Daphne Su-Lyn Gardner

IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Lauren Giuffrida , Kevin Sek , Melissa A Henderson , Imran G House , Junyun Lai , Amanda X Y Chen , Kirsten L Todd , Emma V Petley , Sherly Mardiana , Izabela Todorovski , Emily Gruber , Madison J Kelly , Benjamin J Solomon , Stephin J Vervoort , Ricky W Johnstone , Ian A Parish , Paul J Neeson , Lev M Kats , Phillip K Darcy , Paul A Beavis

T

Science translational medicine

Avec: Deborah Meyran , Joe Jiang Zhu , Jeanne Butler , Daniela Tantalo , Sean MacDonald , Thu Ngoc Nguyen , Minyu Wang , Niko Thio , Criselle D'Souza , Vicky Mengfei Qin , Clare Slaney , Aaron Harrison , Kevin Sek , Pasquale Petrone , Kevin Thia , Lauren Giuffrida , Andrew M Scott , Rachael L Terry , Ben Tran , Jayesh Desai , H Miles Prince , Simon J Harrison , Paul A Beavis , Michael H Kershaw , Ben Solomon , Paul G Ekert , Joseph A Trapani , Phillip K Darcy , Paul J Neeson

Pharmacological and genetic strategies for targeting adenosine to enhance adoptive T cell therapy of cancer.

Current opinion in pharmacology

Avec: Kevin Sek , Lev M Kats , Phillip K Darcy , Paul A Beavis

PTP1B Is an Intracellular Checkpoint that Limits T-cell and CAR T-cell Antitumor Immunity.

Cancer discovery

Avec: Florian Wiede , Kun-Hui Lu , Xin Du , Mara N Zeissig , Rachel Xu , Pei Kee Goh , Chrysovalantou E Xirouchaki , Samuel J Hogarth , Spencer Greatorex , Kevin Sek , Roger J Daly , Paul A Beavis , Phillip K Darcy , Nicholas K Tonks , Tony Tiganis

MAIT cells regulate NK cell-mediated tumor immunity.

Nature communications

Avec: Emma V Petley , Hui-Fern Koay , Melissa A Henderson , Kevin Sek , Kirsten L Todd , Simon P Keam , Junyun Lai , Imran G House , Jasmine Li , Magnus Zethoven , Amanda X Y Chen , Amanda J Oliver , Jessica Michie , Andrew J Freeman , Lauren Giuffrida , Jack D Chan , Angela Pizzolla , Jeffrey Y W Mak , Timothy R McCulloch , Fernando Souza-Fonseca-Guimaraes , Conor J Kearney , Rosemary Millen , Robert G Ramsay , Nicholas D Huntington , James McCluskey , Jane Oliaro , David P Fairlie , Paul J Neeson , Dale I Godfrey , Paul A Beavis , Phillip K Darcy

2021 Asia-Pacific Graves' Disease Consortium Survey of Clinical Practice Patterns in the Management of Graves' Disease.

Endocrine

Avec: Rajeev Parameswaran , Mechteld Christine de Jong , James Lee Wai Kit , Kathleen Sek , Tran Quang Nam , Tran Viet Thang , Nguyen Thy Khue , Than Than Aye , Phone Myint Tun , Timothy Cole , Julie A Miller , Michael Villa , Benjapa Khiewvan , Sirinart Sirinvaravong , Yong Lit Sin , Rohaizak Muhammad , Tjin Shing Jap , Amit Agrawal , Rajesh Rajput , Ranil Fernando , Manilka Sumanatilleke , Ketut Suastika , Young Kee Shong , Brian Lang , Luigi Bartalena , Samantha Peiling Yang , Auteur inconnu

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Nature communications

Avec: Kirsten L Todd , Junyun Lai , Kevin Sek , Yu-Kuan Huang , Dane M Newman , Emily B Derrick , Hui-Fern Koay , Dat Nguyen , Thang X Hoang , Emma V Petley , Cheok Weng Chan , Isabelle Munoz , Imran G House , Joel N Lee , Joelle S Kim , Jasmine Li , Junming Tong , Maria N de Menezes , Christina M Scheffler , Kah Min Yap , Amanda X Y Chen , Phoebe A Dunbar , Brandon Haugen , Ian A Parish , Ricky W Johnstone , Phillip K Darcy , Paul A Beavis

PET/CT of breast cancer regional nodal recurrences: an evaluation of contouring atlases.

Radiation oncology (London, England)

Avec: Laura Beaton , Luminita Nica , Scott Tyldesley , Kenny Sek , Gareth Ayre , Maria Aparicio , Lovedeep Gondara , Caroline Speers , Alan Nichol

Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Imran G House , Peter Savas , Junyun Lai , Amanda X Y Chen , Amanda J Oliver , Zhi L Teo , Kirsten L Todd , Melissa A Henderson , Lauren Giuffrida , Emma V Petley , Kevin Sek , Sherly Mardiana , Tuba N Gide , Camelia Quek , Richard A Scolyer , Georgina V Long , James S Wilmott , Sherene Loi , Phillip K Darcy , Paul A Beavis

Baseline and Post-treatment 18F-Fluorocholine PET/CT Predicts Outcomes in Hepatocellular Carcinoma Following Locoregional Therapy.

Digestive diseases and sciences

Avec: Michael C Wallace , Kenny Sek , Roslyn J Francis , Shaun Samuelson , John Ferguson , Jonathan Tibballs , Ali Asad , David B Preen , Gerry MacQuillan , George Garas , Leon A Adams , Gary P Jeffrey

Adoptive transfer of tumor-specific Th9 cells eradicates heterogeneous antigen-expressing tumor cells.

Cancer cell

Avec: Kevin Sek , Cheok Weng Chan , Paul A Beavis , Phillip K Darcy

Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A.

Cell death & disease

Avec: Andrew M Cobb , Shanelle A De Silva , Robert Hayward , Karolina Sek , Svenja Ulferts , Robert Grosse , Catherine M Shanahan

CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.

Cell reports

Avec: Imran G House , Emily B Derrick , Kevin Sek , Amanda X Y Chen , Jasmine Li , Junyun Lai , Kirsten L Todd , Isabelle Munoz , Jessica Michie , Cheok Weng Chan , Yu-Kuan Huang , Jack D Chan , Emma V Petley , Junming Tong , DatMinh Nguyen , Sven Engel , Peter Savas , Simon J Hogg , Stephin J Vervoort , Conor J Kearney , Marian L Burr , Enid Y N Lam , Omer Gilan , Sammy Bedoui , Ricky W Johnstone , Mark A Dawson , Sherene Loi , Phillip K Darcy , Paul A Beavis

FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy.

Nature

Avec: Jack D Chan , Christina M Scheffler , Isabelle Munoz , Kevin Sek , Joel N Lee , Yu-Kuan Huang , Kah Min Yap , Nicole Y L Saw , Jasmine Li , Amanda X Y Chen , Cheok Weng Chan , Emily B Derrick , Kirsten L Todd , Junming Tong , Phoebe A Dunbar , Jiawen Li , Thang X Hoang , Maria N de Menezes , Emma V Petley , Joelle S Kim , Dat Nguyen , Patrick S K Leung , Joan So , Christian Deguit , Joe Zhu , Imran G House , Lev M Kats , Andrew M Scott , Benjamin J Solomon , Simon J Harrison , Jane Oliaro , Ian A Parish , Kylie M Quinn , Paul J Neeson , Clare Y Slaney , Junyun Lai , Paul A Beavis , Phillip K Darcy

Réseau de co-auteurs

Phillip K Darcy 12 collaborations

Paul A Beavis 12 collaborations

Junyun Lai 8 collaborations

Imran G House 8 collaborations

Amanda X Y Chen 8 collaborations

Kirsten L Todd 8 collaborations

Emma V Petley 8 collaborations

Lauren Giuffrida 6 collaborations

Melissa A Henderson 5 collaborations

Paul J Neeson 5 collaborations

Sherly Mardiana 4 collaborations

Jack D Chan 4 collaborations

Benjamin J Solomon 4 collaborations

Ian A Parish 4 collaborations

Lev M Kats 4 collaborations

Jasmine Li 4 collaborations

Cheok Weng Chan 4 collaborations

Stephin J Vervoort 3 collaborations

Simon J Harrison 3 collaborations

Ricky W Johnstone 3 collaborations

Yu-Kuan Huang 3 collaborations

Emily B Derrick 3 collaborations

Isabelle Munoz 3 collaborations

Junming Tong 3 collaborations

Joseph A Trapani 2 collaborations

Deborah Meyran 2 collaborations

Kathleen Sek 2 collaborations

Andrew M Scott 2 collaborations

Hui-Fern Koay 2 collaborations

Amanda J Oliver 2 collaborations

Jessica Michie 2 collaborations

Conor J Kearney 2 collaborations

Jane Oliaro 2 collaborations

Dat Nguyen 2 collaborations

Thang X Hoang 2 collaborations

Joel N Lee 2 collaborations

Joelle S Kim 2 collaborations

Maria N de Menezes 2 collaborations

Christina M Scheffler 2 collaborations

Kah Min Yap 2 collaborations

Phoebe A Dunbar 2 collaborations

Kenny Sek 2 collaborations

Peter Savas 2 collaborations

Sherene Loi 2 collaborations

Emma M Carrington 1 collaboration

Andrew M Lew 1 collaboration

Katherine Kedzierska 1 collaboration

Maximilien Evrard 1 collaboration

Jason Waithman 1 collaboration

Christina Mølck 1 collaboration

Gregory D Stewart 1 collaboration

Suresh Rama Chandran 1 collaboration

Nabilah Rahman 1 collaboration

Mihir Gandhi 1 collaboration

Ngiap Chuan Tan 1 collaboration

Ian K Y Phoon 1 collaboration

Darren E J Seah 1 collaboration

Ming Hann Cheah 1 collaboration

Daphne Su-Lyn Gardner 1 collaboration

Izabela Todorovski 1 collaboration

Emily Gruber 1 collaboration

Madison J Kelly 1 collaboration

Joe Jiang Zhu 1 collaboration

Jeanne Butler 1 collaboration

Daniela Tantalo 1 collaboration

Sean MacDonald 1 collaboration

Thu Ngoc Nguyen 1 collaboration

Minyu Wang 1 collaboration

Niko Thio 1 collaboration

Criselle D'Souza 1 collaboration

Vicky Mengfei Qin 1 collaboration

Clare Slaney 1 collaboration

Aaron Harrison 1 collaboration

Pasquale Petrone 1 collaboration

Kevin Thia 1 collaboration

Rachael L Terry 1 collaboration

Ben Tran 1 collaboration

Jayesh Desai 1 collaboration

H Miles Prince 1 collaboration

Michael H Kershaw 1 collaboration

Ben Solomon 1 collaboration

Paul G Ekert 1 collaboration

Florian Wiede 1 collaboration

Kun-Hui Lu 1 collaboration

Xin Du 1 collaboration

Mara N Zeissig 1 collaboration

Rachel Xu 1 collaboration

Pei Kee Goh 1 collaboration

Chrysovalantou E Xirouchaki 1 collaboration

Samuel J Hogarth 1 collaboration

Spencer Greatorex 1 collaboration

Roger J Daly 1 collaboration

Nicholas K Tonks 1 collaboration

Tony Tiganis 1 collaboration

Simon P Keam 1 collaboration

Magnus Zethoven 1 collaboration

Andrew J Freeman 1 collaboration

Angela Pizzolla 1 collaboration

Jeffrey Y W Mak 1 collaboration

Timothy R McCulloch 1 collaboration

Fernando Souza-Fonseca-Guimaraes 1 collaboration

Rosemary Millen 1 collaboration

Robert G Ramsay 1 collaboration

Nicholas D Huntington 1 collaboration

James McCluskey 1 collaboration

David P Fairlie 1 collaboration

Dale I Godfrey 1 collaboration

Rajeev Parameswaran 1 collaboration

Mechteld Christine de Jong 1 collaboration

James Lee Wai Kit 1 collaboration

Tran Quang Nam 1 collaboration

Tran Viet Thang 1 collaboration

Nguyen Thy Khue 1 collaboration

Than Than Aye 1 collaboration

Phone Myint Tun 1 collaboration

Timothy Cole 1 collaboration

Julie A Miller 1 collaboration

Michael Villa 1 collaboration

Benjapa Khiewvan 1 collaboration

Sirinart Sirinvaravong 1 collaboration

Yong Lit Sin 1 collaboration

Rohaizak Muhammad 1 collaboration

Tjin Shing Jap 1 collaboration

Amit Agrawal 1 collaboration

Rajesh Rajput 1 collaboration

Ranil Fernando 1 collaboration

Manilka Sumanatilleke 1 collaboration

Ketut Suastika 1 collaboration

Young Kee Shong 1 collaboration

Brian Lang 1 collaboration

Luigi Bartalena 1 collaboration

Samantha Peiling Yang 1 collaboration

None None 1 collaboration

Dane M Newman 1 collaboration

Brandon Haugen 1 collaboration

Laura Beaton 1 collaboration

Luminita Nica 1 collaboration

Scott Tyldesley 1 collaboration

Gareth Ayre 1 collaboration

Maria Aparicio 1 collaboration

Lovedeep Gondara 1 collaboration

Caroline Speers 1 collaboration

Alan Nichol 1 collaboration

Zhi L Teo 1 collaboration

Tuba N Gide 1 collaboration

Camelia Quek 1 collaboration

Richard A Scolyer 1 collaboration

Georgina V Long 1 collaboration

James S Wilmott 1 collaboration

Michael C Wallace 1 collaboration

Roslyn J Francis 1 collaboration

Shaun Samuelson 1 collaboration

John Ferguson 1 collaboration

Jonathan Tibballs 1 collaboration

Ali Asad 1 collaboration

David B Preen 1 collaboration

Gerry MacQuillan 1 collaboration

George Garas 1 collaboration

Leon A Adams 1 collaboration

Gary P Jeffrey 1 collaboration

Andrew M Cobb 1 collaboration

Shanelle A De Silva 1 collaboration

Robert Hayward 1 collaboration

Karolina Sek 1 collaboration

Svenja Ulferts 1 collaboration

Robert Grosse 1 collaboration

Catherine M Shanahan 1 collaboration

DatMinh Nguyen 1 collaboration

Sven Engel 1 collaboration

Simon J Hogg 1 collaboration

Marian L Burr 1 collaboration

Enid Y N Lam 1 collaboration

Omer Gilan 1 collaboration

Sammy Bedoui 1 collaboration

Mark A Dawson 1 collaboration

Nicole Y L Saw 1 collaboration

Jiawen Li 1 collaboration

Patrick S K Leung 1 collaboration

Joan So 1 collaboration

Christian Deguit 1 collaboration

Joe Zhu 1 collaboration

Kylie M Quinn 1 collaboration

Clare Y Slaney 1 collaboration