Ph-like acute lymphoblastic leukemia in adults: understanding pathogenesis, improving outcomes, and future directions for therapy.

Humans Adult Philadelphia Chromosome Philadelphia Precursor Cell Lymphoblastic Leukemia-Lymphoma / etiology Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy Remission Induction Protein Kinase Inhibitors / therapeutic use
Acute lymphoblastic leukemia CRLF2 Ph-like ALL philadelphia-like

Journal

Leukemia & lymphoma
ISSN: 1029-2403
Titre abrégé: Leuk Lymphoma
Pays: United States
ID NLM: 9007422

Informations de publication

Date de publication:
06 2023
Historique:
medline: 13 6 2023
pubmed: 7 4 2023
entrez: 6 4 2023
Statut: ppublish

Résumé

Philadelphia (Ph)-like acute lymphoblastic leukemia (ALL) is a high-risk subgroup of B cell ALL with distinct genotypes, unified by gene expression profile similar to Ph-positive ALL, but lacking the

Identifiants

DOI: 10.1080/10428194.2023.2197538 PMID: 37021793
pubmed: 37021793
doi: 10.1080/10428194.2023.2197538
doi:

Substances chimiques

Protein Kinase Inhibitors 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1092-1101

Auteurs

Ibrahim Aldoss (I)

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA, USA.

Zhaohui Gu (Z)

Department of Systems Biology, Beckman Research Institute of City of Hope, Duarte, CA, USA.

Michelle Afkhami (M)

Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA.

Sally Mokhtari (S)

Department of Clinical and Translational Project Development, City of Hope National Medical Center, Duarte, CA, USA.

Vinod Pullarkat (V)

Department of Hematology and Hematopoietic Cell Transplantation, Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Aberrations des chromosomes › Chromosome Philadelphie › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Régions géographiques › Villes › Philadelphie › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Leucémie lymphoïde › Leucémie-lymphome lymphoblastique à précurseurs B et T › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Maladies du système immunitaire › Syndromes immunoprolifératifs › Syndromes lymphoprolifératifs › Leucémie lymphoïde › Leucémie-lymphome lymphoblastique à précurseurs B et T › Leucémie-lymphome lymphoblastique à précurseurs B › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Thérapeutique › Induction de rémission › Ph-like acute lymphoblastic leukemia in...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Inhibiteurs de protéines kinases › Ph-like acute lymphoblastic leukemia in...