[Hospitalization for infection in patients treated for giant cell arteritis: A single-centre retrospective study].
Hospitalisation pour infection chez les patients suivis pour une artérite à cellules géantes : étude monocentrique rétrospective.
Artérite à cellules géantes
Corticoïdes
Giant cell arteritis
Glucocorticoids
Horton's Disease
Infections
Maladie de Horton
Vascularite
Vasculitis
Journal
La Revue de medecine interne
ISSN: 1768-3122
Titre abrégé: Rev Med Interne
Pays: France
ID NLM: 8101383
Informations de publication
Date de publication:
May 2023
May 2023
Historique:
received:
15
11
2022
revised:
06
02
2023
accepted:
07
02
2023
medline:
15
5
2023
pubmed:
8
4
2023
entrez:
7
4
2023
Statut:
ppublish
Résumé
Infections are associated with morbimortality of patients with giant cell arteritis (GCA). The aim of this work was twofold: the identification of factors predisposing to the risk of infection and the description of patients hospitalized with an infection occurring during the treatment period of CAG. A monocentric retrospective study was conducted in GCA patients, comparing patients hospitalized for infection with patients without infection. The analysis included 21/144 (14.6%) patients with 26 infections (cases) and 42 control matched on sex, age, and diagnosis of GCA. Both groups were similar except for a higher frequency of seritis in cases (15% vs. 0%, p=0.03). Relapses of GCA were less common in cases (23.8% vs 50.0%, p=0.041). Hypogammaglobulinemia was present during infection. More than half of the infections (53.8%) occurred in the first year of follow-up with an average dose of 15mg/day of corticosteroids. Infections were mainly pulmonary (46.2%) and cutaneous (26.9%). Factors associated with infectious risk were identified. This preliminary monocentric work will continue with a national multicentre study.
Identifiants
pubmed: 37029032
pii: S0248-8663(23)00063-2
doi: 10.1016/j.revmed.2023.02.002
pii:
doi:
Substances chimiques
Glucocorticoids
0
Adrenal Cortex Hormones
0
Types de publication
Multicenter Study
English Abstract
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
212-217Informations de copyright
Copyright © 2023 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.