Analgesic efficacy of selective tibial nerve block versus partial local infiltration analgesia for posterior pain after total knee arthroplasty: a randomized, controlled, triple-blinded trial.


Journal

Anaesthesia, critical care & pain medicine
ISSN: 2352-5568
Titre abrégé: Anaesth Crit Care Pain Med
Pays: France
ID NLM: 101652401

Informations de publication

Date de publication:
08 2023
Historique:
received: 12 02 2023
revised: 28 02 2023
accepted: 19 03 2023
medline: 23 10 2023
pubmed: 9 4 2023
entrez: 8 4 2023
Statut: ppublish

Résumé

The adductor canal block provides pain relief on the anterior aspect of the knee after arthroplasty. Pain on the posterior aspect may be treated either by partial local infiltration analgesia of the posterior capsule or by a tibial nerve block. This randomized, controlled, triple-blinded trial tests the hypothesis that a tibial nerve block would provide superior analgesia compared to posterior capsule infiltration in patients scheduled for total knee arthroplasty under spinal anesthesia with an adductor canal block. Sixty patients were randomized to receive either infiltration of the posterior capsule by the surgeon with ropivacaine 0.2%, 25 mL, or a tibial nerve block with 10 mL of ropivacaine 0.5%. Sham injections were performed to guarantee proper blinding. The primary outcome was intravenous morphine consumption at 24 h. Secondary outcomes included intravenous morphine consumption, pain scores at rest and on movement, and different functional outcomes, measured at up to 48 h. When necessary, longitudinal analyses were performed with a mixed-effects linear model. The median (interquartile range) of cumulative intravenous morphine consumption at 24 h was 12 mg (4-16) and 8 mg (2-14) in patients having the infiltration or the tibial nerve block respectively (p = 0.20). Our longitudinal model showed a significant interaction between group and time in favor of the tibial nerve block (p = 0.015). No significant differences were present between groups in the other above-mentioned secondary outcomes. A tibial nerve block does not provide superior analgesia when compared to infiltration. However, a tibial nerve block might be associated with a slower increase in morphine consumption over time.

Sections du résumé

BACKGROUND
The adductor canal block provides pain relief on the anterior aspect of the knee after arthroplasty. Pain on the posterior aspect may be treated either by partial local infiltration analgesia of the posterior capsule or by a tibial nerve block. This randomized, controlled, triple-blinded trial tests the hypothesis that a tibial nerve block would provide superior analgesia compared to posterior capsule infiltration in patients scheduled for total knee arthroplasty under spinal anesthesia with an adductor canal block.
METHODS
Sixty patients were randomized to receive either infiltration of the posterior capsule by the surgeon with ropivacaine 0.2%, 25 mL, or a tibial nerve block with 10 mL of ropivacaine 0.5%. Sham injections were performed to guarantee proper blinding. The primary outcome was intravenous morphine consumption at 24 h. Secondary outcomes included intravenous morphine consumption, pain scores at rest and on movement, and different functional outcomes, measured at up to 48 h. When necessary, longitudinal analyses were performed with a mixed-effects linear model.
RESULTS
The median (interquartile range) of cumulative intravenous morphine consumption at 24 h was 12 mg (4-16) and 8 mg (2-14) in patients having the infiltration or the tibial nerve block respectively (p = 0.20). Our longitudinal model showed a significant interaction between group and time in favor of the tibial nerve block (p = 0.015). No significant differences were present between groups in the other above-mentioned secondary outcomes.
CONCLUSION
A tibial nerve block does not provide superior analgesia when compared to infiltration. However, a tibial nerve block might be associated with a slower increase in morphine consumption over time.

Identifiants

pubmed: 37030393
pii: S2352-5568(23)00031-0
doi: 10.1016/j.accpm.2023.101223
pii:
doi:

Substances chimiques

Ropivacaine 7IO5LYA57N
Anesthetics, Local 0
Analgesics, Opioid 0
Analgesics 0
Morphine 76I7G6D29C

Types de publication

Randomized Controlled Trial Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

101223

Informations de copyright

Copyright © 2023 The Authors. Published by Elsevier Masson SAS.. All rights reserved.

Auteurs

F Paulou (F)

Department of Anaesthesia, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

J Wegrzyn (J)

Department of Orthopaedic Surgery, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

J B Rossel (JB)

Centre for Primary Care and Public Health (Unisanté), University of Lausanne, Lausanne, Switzerland.

E Gonvers (E)

Department of Anaesthesia, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

A Antoniadis (A)

Department of Orthopaedic Surgery, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

M Kägi (M)

Department of Orthopaedic Surgery, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

M R Wolmarans (MR)

Department of Anaesthesia, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

J Lambert (J)

Department of Orthopaedic Surgery, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland.

E Albrecht (E)

Department of Anaesthesia, University Hospital of Lausanne and University of Lausanne, Lausanne, Switzerland. Electronic address: eric.albrecht@chuv.ch.

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Classifications MeSH