CO

Appetitive conditioning CO(2) Extinction Individual differences Orexin

Journal

Physiology & behavior
ISSN: 1873-507X
Titre abrégé: Physiol Behav
Pays: United States
ID NLM: 0151504

Informations de publication

Date de publication:
01 07 2023
Historique:
received: 21 12 2022
revised: 17 03 2023
accepted: 04 04 2023
medline: 8 5 2023
pubmed: 10 4 2023
entrez: 9 4 2023
Statut: ppublish

Résumé

Pavlovian conditioning can underly the maladaptive behaviors seen in psychiatric disorders such as anxiety and addiction. In both the lab and the clinic, these responses can be attenuated through extinction learning, but often return with the passage of time, stress, or a change in context. Extinction to fear and reward cues are both subject to these return of behavior phenomena and have overlap in neurocircuitry, yet it is unknown whether they share any common predictors. The orexin system has been implicated in both fear and appetitive extinction and can be activated through a CO

Identifiants

pubmed: 37031791
pii: S0031-9384(23)00111-7
doi: 10.1016/j.physbeh.2023.114183
pii:
doi:

Substances chimiques

Orexins 0
Carbon Dioxide 142M471B3J

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

114183

Subventions

Organisme : NIMH NIH HHS
ID : R01 MH125951
Pays : United States
Organisme : NIMH NIH HHS
ID : R01 MH125949
Pays : United States
Organisme : NIDA NIH HHS
ID : T32 DA018926
Pays : United States

Informations de copyright

Copyright © 2023 The Author(s). Published by Elsevier Inc. All rights reserved.

Auteurs

Marissa Raskin (M)

The University of Texas at Austin, Institute for Neuroscience, United States.

Cassidy Malone (C)

The University of Texas at Austin, Department of Psychology, United States.

Emily N Hilz (EN)

The University of Texas at Austin, Department of Psychology, United States.

Jasper A J Smits (JAJ)

The University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.

Michael J Telch (MJ)

The University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.

Michael W Otto (MW)

Boston University, United States.

Jason Shumake (J)

The University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States.

Hongjoo J Lee (HJ)

The University of Texas at Austin, Institute for Neuroscience, United States; The University of Texas at Austin, Department of Psychology, United States.

Marie-H Monfils (MH)

The University of Texas at Austin, Institute for Neuroscience, United States; The University of Texas at Austin, Department of Psychology, United States; The University of Texas at Austin, Institute for Mental Health Research, United States. Electronic address: marie.monfils@utexas.edu.

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Classifications MeSH