Lipid peroxidation in diamond supported bilayers.


Journal

Nanoscale
ISSN: 2040-3372
Titre abrégé: Nanoscale
Pays: England
ID NLM: 101525249

Informations de publication

Date de publication:
04 May 2023
Historique:
medline: 5 5 2023
pubmed: 18 4 2023
entrez: 17 4 2023
Statut: epublish

Résumé

Lipid peroxidation is a process that occurs in cells when they are exposed to oxidative stress. During the process reactive oxygen species attack lipids within the lipid bilayers of cells. Since the products of lipid peroxidation are toxic and carcinogenic, it is important to understand where and how it occurs with nanoscale resolution. The radical intermediates of this process are particularly interesting since they are causing chain reactions damaging large parts of the lipid membranes in cells. However, they are also difficult to measure for the state of the art because they are short lived and reactive. Here, we study the lipid peroxidation of three artificial lipid bilayers on a diamonds substrate that can be used to study lipid peroxidation. In particular, we present a diamond quantum sensing method called

Identifiants

pubmed: 37067002
doi: 10.1039/d3nr01167d
pmc: PMC10273028
doi:

Substances chimiques

Lipid Bilayers 0
Reactive Oxygen Species 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7920-7928

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Auteurs

A R Ortiz Moreno (AR)

Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, the Netherlands. romana.schirhagl@gmail.com.

R Li (R)

Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, the Netherlands. romana.schirhagl@gmail.com.

K Wu (K)

Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, the Netherlands. romana.schirhagl@gmail.com.

R Schirhagl (R)

Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, the Netherlands. romana.schirhagl@gmail.com.

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Classifications MeSH