A Single Residue within the MCR-1 Protein Confers Anticipatory Resilience.

Colistin / pharmacology Lipid A Anti-Bacterial Agents / pharmacology Escherichia coli Escherichia coli Proteins / genetics Plasmids Peptide Hydrolases / pharmacology Drug Resistance, Bacterial / genetics Microbial Sensitivity Tests
E. coli MCR-1 envelope stress response (ESR) lipid A mass spectrometry pH-enhanced resistance plasmid elimination

Journal

Microbiology spectrum
ISSN: 2165-0497
Titre abrégé: Microbiol Spectr
Pays: United States
ID NLM: 101634614

Informations de publication

Date de publication:
15 06 2023
Historique:
medline: 19 6 2023
pubmed: 19 4 2023
entrez: 18 4 2023
Statut: ppublish

Résumé

The envelope stress response (ESR) of Gram-negative enteric bacteria senses fluctuations in nutrient availability and environmental changes to avert damage and promote survival. It has a protective role toward antimicrobials, but direct interactions between ESR components and antibiotic resistance genes have not been demonstrated. Here, we report interactions between a central regulator of ESR

Identifiants

DOI: 10.1128/spectrum.03592-22 PMID: 37071007 PMC: PMC10269488
pubmed: 37071007
doi: 10.1128/spectrum.03592-22
pmc: PMC10269488
doi:

Substances chimiques

Colistin Z67X93HJG1
Lipid A 0
Anti-Bacterial Agents 0
Escherichia coli Proteins 0
Peptide Hydrolases EC 3.4.-
MCR-1 protein, E coli 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0359222

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Références

Antibiotics (Basel). 2021 Jul 19;10(7):
pubmed: 34356793
Microbiol Spectr. 2022 Oct 26;10(5):e0174822
pubmed: 35980194
Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2218-2223
pubmed: 28193899
Gene. 1990 Mar 30;88(1):121-6
pubmed: 2187746
Proc Natl Acad Sci U S A. 2000 Jun 6;97(12):6640-5
pubmed: 10829079
Genome Biol. 2011;12(1):R8
pubmed: 21247462
J Biol Chem. 2011 Sep 2;286(35):30680-30690
pubmed: 21685389
J Gen Physiol. 1969 Jul 1;54(1):95-113
pubmed: 19873660
Future Microbiol. 2020 Apr;15:445-459
pubmed: 32250173
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W320-4
pubmed: 24753421
EBioMedicine. 2018 Aug;34:139-157
pubmed: 30061009
Lancet Infect Dis. 2016 Mar;16(3):282-3
pubmed: 26774242
Antimicrob Agents Chemother. 2017 Mar 24;61(4):
pubmed: 28137796
Int Microbiol. 2020 Aug;23(3):355-366
pubmed: 31872322
Front Microbiol. 2020 Oct 09;11:588658
pubmed: 33162965
Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17775-9
pubmed: 16303867
Int J Mol Sci. 2022 Feb 11;23(4):
pubmed: 35216122
Science. 2021 Aug 20;373(6557):871-876
pubmed: 34282049
Sci Rep. 2017 Jan 06;7:39392
pubmed: 28059088
Appl Environ Microbiol. 2015 Mar;81(6):1932-41
pubmed: 25556191
Oncotarget. 2017 Nov 20;8(64):107596-107602
pubmed: 29296190
Emerg Microbes Infect. 2020 Dec;9(1):508-516
pubmed: 32116151
Proc Natl Acad Sci U S A. 1989 Sep;86(18):6973-7
pubmed: 2674941
Mol Syst Biol. 2006;2:2006.0008
pubmed: 16738554
Genes Dev. 1997 May 1;11(9):1169-82
pubmed: 9159398
Trends Biochem Sci. 2017 Mar;42(3):232-242
pubmed: 27839654
Plasmid. 1991 May;25(3):221-4
pubmed: 1924559
Bioinformatics. 2012 Apr 15;28(8):1166-7
pubmed: 22368248
J Biol Chem. 2002 Jul 19;277(29):26652-61
pubmed: 11953442
Commun Biol. 2020 Oct 1;3(1):547
pubmed: 33005001
Emerg Microbes Infect. 2020 Dec;9(1):868-885
pubmed: 32284036
Nat Commun. 2020 Mar 20;11(1):1496
pubmed: 32198415
J Bacteriol. 2003 Apr;185(8):2432-40
pubmed: 12670966
Gene. 2006 Sep 1;379:109-15
pubmed: 16750601
Nat Rev Microbiol. 2019 Jul;17(7):417-428
pubmed: 31150012
J Mol Biol. 2007 Oct 19;373(2):367-81
pubmed: 17825319
Nat Commun. 2023 Jan 10;14(1):140
pubmed: 36627272
Emerg Microbes Infect. 2022 Dec;11(1):1236-1249
pubmed: 35437117
J Glob Antimicrob Resist. 2022 Jun;29:444-461
pubmed: 34788692
Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1414-1418
pubmed: 31907318
Cell Rep. 2021 May 18;35(7):109135
pubmed: 34010644
J Antimicrob Chemother. 2018 Jun 1;73(6):1604-1610
pubmed: 29514208
Biochim Biophys Acta. 2014 Aug;1843(8):1529-41
pubmed: 24184210
Nucleic Acids Res. 2001 May 1;29(9):e45
pubmed: 11328886
FEBS J. 2018 Sep;285(18):3525-3538
pubmed: 30085413
Cell. 2020 Feb 20;180(4):688-702.e13
pubmed: 32084340
Front Microbiol. 2014 Nov 26;5:643
pubmed: 25505462
Trends Microbiol. 2018 Sep;26(9):794-808
pubmed: 29525421
J Microbiol. 2015 May;53(5):306-10
pubmed: 25935301
J Antimicrob Chemother. 2020 Nov 1;75(11):3087-3095
pubmed: 32514524
Mol Biol Evol. 2016 Jul;33(7):1870-4
pubmed: 27004904
Front Cell Infect Microbiol. 2017 Jun 08;7:242
pubmed: 28642846
Int J Antimicrob Agents. 2018 Apr;51(4):554-561
pubmed: 29180279
J Lipid Res. 2005 Aug;46(8):1773-8
pubmed: 15930524
Nat Methods. 2009 May;6(5):343-5
pubmed: 19363495
Sci Rep. 2016 Dec 13;6:38793
pubmed: 27958270
Nature. 2008 Jun 12;453(7197):885-90
pubmed: 18496527
Nat Commun. 2017 Dec 12;8(1):2054
pubmed: 29233990
Front Cell Infect Microbiol. 2019 Sep 04;9:313
pubmed: 31552196
Lancet Infect Dis. 2016 Feb;16(2):161-8
pubmed: 26603172
Int J Antimicrob Agents. 2018 May;51(5):739-744
pubmed: 29409993
Biochem Biophys Res Commun. 2002 Jan 11;290(1):397-402
pubmed: 11779182
Drug Discov Today. 2019 Jan;24(1):206-216
pubmed: 30036574

Auteurs

Renate Frantz (R)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.

Konrad Gwozdzinski (K)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.

Nicolas Gisch (N)

Division of Bioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
ORCID: 0000-0003-3260-5269

Swapnil Prakash Doijad (SP)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.
ORCID: 0000-0002-0932-8542

Martina Hudel (M)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.

Maria Wille (M)

Institute of Hygiene and Environmental Medicine, Justus Liebig University Giessen, Giessen, Germany.

Mobarak Abu Mraheil (M)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.

Dominik Schwudke (D)

Division of Bioanalytical Chemistry, Priority Area Infections, Research Center Borstel, Leibniz Lung Center, Borstel, Germany.
German Center for Infection Research, Partner Site: Hamburg-Lübeck-Borstel-Riems, Borstel, Germany.
Airway Research Center North, Partner Site: Research Center Borstel, Borstel, Germany.
ORCID: 0000-0002-1379-9451

Can Imirzalioglu (C)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
Hessian University Competence Center for Hospital Hygiene, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.

Linda Falgenhauer (L)

Institute of Hygiene and Environmental Medicine, Justus Liebig University Giessen, Giessen, Germany.
Hessian University Competence Center for Hospital Hygiene, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.

Michael Ehrmann (M)

Center of Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Essen, Germany.
School of Biosciences, Cardiff University, Cardiff, United Kingdom.

Trinad Chakraborty (T)

Institute of Medical Microbiology, Justus Liebig University Giessen, Giessen, Germany.
Hessian University Competence Center for Hospital Hygiene, Justus Liebig University Giessen, Giessen, Germany.
German Center for Infection Research, Partner Site: Giessen-Marburg-Langen, Giessen, Germany.
ORCID: 0000-0002-1452-4759

Articles similaires

Vancomycin-associated DRESS demonstrates delay in AST abnormalities.

Ahmed Hussein, Kateri L Schoettinger, Jourdan Hydol-Smith et al.
1.00
Humans Drug Hypersensitivity Syndrome Vancomycin Female Male

Management of the infected total elbow arthroplasty.

Joaquin Sanchez-Sotelo
1.00
Humans Arthroplasty, Replacement, Elbow Prosthesis-Related Infections Debridement Anti-Bacterial Agents

Mathematical modeling of vancomycin release from Poly-L-Lactic Acid-Coated implants.

Papon Thamvasupong, Kwanchanok Viravaidya-Pasuwat
1.00
Vancomycin Polyesters Anti-Bacterial Agents Models, Theoretical Drug Liberation

Menthol as an effective inhibitor of quorum sensing and biofilm formation in Candida albicans and Candida glabrata by targeting the transcriptional repressor TUP1.

Pouria Khodavandi, Maryam Miri Soogh, Fahimeh Alizadeh et al.
1.00
Biofilms Candida albicans Quorum Sensing Candida glabrata Menthol

Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Perforines › Peptides antimicrobiens cationiques › Polymyxines › Colistine › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Toxines bactériennes › Endotoxines › Lipopolysaccharides › Lipide A › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Escherichia › Escherichia coli › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › Protéines Escherichia coli › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Phénomènes génétiques › Structures génétiques › Plasmides › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Peptide hydrolases › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Résistance aux substances › Résistance microbienne aux médicaments › Résistance bactérienne aux médicaments › A Single Residue within the MCR-1 Protein...
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › A Single Residue within the MCR-1 Protein...