Indications for Fusion With Intradural Spine Tumor Resection in Adults: A Systematic Review and Meta-analysis.


Journal

World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 31 03 2023
revised: 08 04 2023
accepted: 10 04 2023
medline: 9 8 2023
pubmed: 21 4 2023
entrez: 20 04 2023
Statut: ppublish

Résumé

The evidence for instrumented fusion in the setting of degenerative, traumatic, or congenital deformity is well established. Data on fusion indications in intradural spinal tumors (IDST) are scarce and reduced to retrospective studies. The objective of this work is to systematically review the published literature since 2015 and analyze the change of practice patterns for stabilization and fusion after intradural tumor resection in adults. A systematic literature review was performed via PubMed with the terms: "intradural spinal tumors", "intramedullary spinal tumors", and "intraspinal tumors". The analysis was limited to adult patients with IDST and studies with more than 10 patients. Data on the proportion of patients who underwent instrumentation and had postoperative deformity was pooled in a meta-analysis. A total of 1073 articles were identified and 47 papers were selected. All the studies were retrospective series and a total of 2473 patients were included. The follow-up ranged from 1 to 96 months, the pooled spinal fixation rate was 6% (95% CI 4.5%-7.6%), the pooled laminoplasty rate was 14.4% (95% CI 5.9%-23%), the pooled rate of postoperative deformity or malalignment in patients with a follow up of at least 6 months was 2.1% (95% CI 1.2%-3%) and just 7 patients were reoperated due to progressive deformity. Based on existing evidence, the rate of fusion during resection of intradural spinal tumors is low. Prophylactic fixation is often unnecessary and only indicated in unique cases that require extensive bony resection.

Sections du résumé

BACKGROUND BACKGROUND
The evidence for instrumented fusion in the setting of degenerative, traumatic, or congenital deformity is well established. Data on fusion indications in intradural spinal tumors (IDST) are scarce and reduced to retrospective studies. The objective of this work is to systematically review the published literature since 2015 and analyze the change of practice patterns for stabilization and fusion after intradural tumor resection in adults.
METHODS METHODS
A systematic literature review was performed via PubMed with the terms: "intradural spinal tumors", "intramedullary spinal tumors", and "intraspinal tumors". The analysis was limited to adult patients with IDST and studies with more than 10 patients. Data on the proportion of patients who underwent instrumentation and had postoperative deformity was pooled in a meta-analysis.
RESULTS RESULTS
A total of 1073 articles were identified and 47 papers were selected. All the studies were retrospective series and a total of 2473 patients were included. The follow-up ranged from 1 to 96 months, the pooled spinal fixation rate was 6% (95% CI 4.5%-7.6%), the pooled laminoplasty rate was 14.4% (95% CI 5.9%-23%), the pooled rate of postoperative deformity or malalignment in patients with a follow up of at least 6 months was 2.1% (95% CI 1.2%-3%) and just 7 patients were reoperated due to progressive deformity.
CONCLUSIONS CONCLUSIONS
Based on existing evidence, the rate of fusion during resection of intradural spinal tumors is low. Prophylactic fixation is often unnecessary and only indicated in unique cases that require extensive bony resection.

Identifiants

pubmed: 37080455
pii: S1878-8750(23)00526-0
doi: 10.1016/j.wneu.2023.04.041
pii:
doi:

Types de publication

Systematic Review Meta-Analysis Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

21-30

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Esteban Quiceno (E)

Department of Neurosurgery, Banner University Medical Center, Phoenix, AZ, USA; Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA. Electronic address: equicenor@gmail.com.

Amna Hussein (A)

Department of Neurosurgery, Banner University Medical Center, Phoenix, AZ, USA; Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Annie Pico (A)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Ebtesam Abdulla (E)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Isabel L Bauer (IL)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Kristin Nosova (K)

Department of Neurosurgery, Banner University Medical Center, Phoenix, AZ, USA; Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Alexandros Moniakis (A)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Monis Ahmed Khan (MA)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Dara S Farhadi (DS)

Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

Michael Prim (M)

Department of Neurosurgery, Banner University Medical Center, Phoenix, AZ, USA.

Ali Baaj (A)

Department of Neurosurgery, Banner University Medical Center, Phoenix, AZ, USA; Department of Neurosurgery, University of Arizona College of Medicine, Phoenix, AZ, USA.

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Classifications MeSH