Immediate major dynamic changes in the T- and NK-cell subset composition after cardiac transplantation.
Chimerism
NK cells
heart transplantation
naïve and memory T cells
passenger leukocytes
Journal
European journal of immunology
ISSN: 1521-4141
Titre abrégé: Eur J Immunol
Pays: Germany
ID NLM: 1273201
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
revised:
23
03
2023
received:
21
07
2022
accepted:
28
04
2023
medline:
17
7
2023
pubmed:
29
4
2023
entrez:
29
4
2023
Statut:
ppublish
Résumé
Early kinetics of lymphocyte subsets involved in tolerance and rejection following heart transplantation (HTx) are barely defined. Here, we aimed to delineate the early alloimmune response immediately after HTx. Therefore, blood samples from 23 heart-transplanted patients were collected before (pre-), immediately (T0), 24 hours (T24), and 3 weeks (3 wks) after HTx. Immunophenotyping was performed using flow cytometry. A significant increase was detected for terminally differentiated (TEMRA) CD4
Identifiants
pubmed: 37119053
doi: 10.1002/eji.202250097
doi:
Substances chimiques
CD56 Antigen
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2250097Subventions
Organisme : German Research Foundation
ID : DFG SFB738 B3
Organisme : German Ministry for Education and Research
ID : BMBF IFB-Tx BMBF 01EO1302
Organisme : German Center for Infection Research
ID : DZIF TTU-IICH
Organisme : Berlin Institute of Health Junior Clinician Scientist Program
Informations de copyright
© 2023 The Authors. European Journal of Immunology published by Wiley-VCH GmbH.
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