Myocardial Fatigue at a Glance.


Journal

Current heart failure reports
ISSN: 1546-9549
Titre abrégé: Curr Heart Fail Rep
Pays: United States
ID NLM: 101196487

Informations de publication

Date de publication:
Jun 2023
Historique:
accepted: 21 04 2023
medline: 12 6 2023
pubmed: 3 5 2023
entrez: 3 5 2023
Statut: ppublish

Résumé

Expanding on the modern lexicon of heart failure (HF), the novel mechano-energetic concept of myocardial fatigue describes a transiently energy-depleted myocardium with impaired contractility and relaxation in the face of adverse haemodynamic load. It encompasses established concepts of ventricular-arterial decoupling, deranged cardiac energetics and impaired myocardial efficiency, offering an alternative explanation for functional causes of HF.

Identifiants

pubmed: 37133679
doi: 10.1007/s11897-023-00603-3
pii: 10.1007/s11897-023-00603-3
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

191-193

Informations de copyright

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Références

Tran P, Maddock H, Banerjee P. Myocardial fatigue: a mechano-energetic concept in heart failure. Curr Cardiol Rep. 2022;24(6):711–30.  https://doi.org/10.1007/s11886-022-01689-2
Lemon DD, Papst PJ, Joly K, et al. A high-performance liquid chromatography assay for quantification of cardiac myosin heavy chain isoform protein expression. Anal Biochem. 2011;408(1):132–5.
doi: 10.1016/j.ab.2010.08.041 pubmed: 20816744
Sundberg CW, Fitts RH. Bioenergetic basis of skeletal muscle fatigue. Curr Opin Physiol. 2019;10:118–27.
doi: 10.1016/j.cophys.2019.05.004 pubmed: 31342000 pmcid: 6656370
McDonald KS, Hanft LM, Robinett JC, et al. Regulation of myofilament contractile function in human donor and failing hearts. Front Physiol. 2020;11:468.
doi: 10.3389/fphys.2020.00468 pubmed: 32523542 pmcid: 7261867
Blair CA, Brundage EA, Thompson KL, Stromberg A, Guglin M, Biesiadecki BJ, et al. Heart failure in humans reduces contractile force in myocardium from both ventricles. JACC Basic Transl Sci. 2020;5(8):786–98.
doi: 10.1016/j.jacbts.2020.05.014 pubmed: 32875169 pmcid: 7452203
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doi: 10.1016/j.jacc.2004.09.044 pubmed: 15607403
Kleinnibbelink G, van Dijk APJ, Fornasiero A, Speretta GF, Johnson C, Hopman MTE, Sculthorpe N, George KP, Somauroo JD, Thijssen DHJ, Oxborough DL. Exercise-induced cardiac fatigue after a 45-minute bout of high-intensity running exercise is not altered under hypoxia. J Am Soc Echocardiogr. 2021;34(5):511–21.  https://doi.org/10.1016/j.echo.2020.12.003
Tran P, Joshi M, Banerjee P. Concept of myocardial fatigue in reversible severe left ventricular systolic dysfunction from afterload mismatch: a case series. Eur Heart J Case Rep. 2021;5(3):ytab089. https://doi.org/10.1093/ehjcr/ytab089
Burkhoff D, Topkara VK, Sayer G, Uriel N. Reverse remodeling with left ventricular assist devices. Circ Res. 2021;128(10):1594–612.

Auteurs

Patrick Tran (P)

University Hospital Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK. patrick.tran@nhs.net.
Centre for Sport, Exercise, Life Sciences, Faculty of Health and Life Sciences, Coventry University, Alison Gingell Building, Coventry, CV1 2DS, UK. patrick.tran@nhs.net.

Prithwish Banerjee (P)

University Hospital Coventry and Warwickshire, Clifford Bridge Road, Coventry, CV2 2DX, UK.
Centre for Sport, Exercise, Life Sciences, Faculty of Health and Life Sciences, Coventry University, Alison Gingell Building, Coventry, CV1 2DS, UK.
Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.

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Classifications MeSH