Molecular probes for fluorescent sensing of metal ions in non-mammalian organisms.

Bacterial imaging C. elegans imaging Fluorescent metal sensor Plant imaging Yeast imaging Zebrafish imaging

Journal

Current opinion in chemical biology
ISSN: 1879-0402
Titre abrégé: Curr Opin Chem Biol
Pays: England
ID NLM: 9811312

Informations de publication

Date de publication:
06 2023
Historique:
received: 22 11 2022
revised: 16 03 2023
accepted: 29 03 2023
medline: 30 5 2023
pubmed: 6 5 2023
entrez: 5 5 2023
Statut: ppublish

Résumé

While metal ions play an important role in the proper functioning of all life, many questions remain unanswered about exactly how different metals contribute to health and disease. The development of fluorescent probes, which respond to metals, has allowed greater understanding of the cellular location, concentration and speciation of metals in living systems, giving a new appreciation of their function. While the focus of studies using these fluorescent tools has largely been on mammalian organisms, there has been relatively little application of these powerful tools to other organisms. In this review, we highlight recent examples of molecular fluorophores, which have been applied to sensing metals in non-mammalian organisms.

Identifiants

pubmed: 37146433
pii: S1367-5931(23)00049-2
doi: 10.1016/j.cbpa.2023.102311
pii:
doi:

Substances chimiques

Molecular Probes 0
Metals 0
Fluorescent Dyes 0
Ions 0

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

102311

Informations de copyright

Copyright © 2023 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Tom Hawtrey (T)

School of Chemistry, The University of Sydney, NSW 2006, Australia; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, NSW 2006, Australia; The University of Sydney Nano Institute (Sydney Nano), The University of Sydney, NSW 2006, Australia. Electronic address: tom.hawtrey@sydney.edu.au.

Elizabeth J New (EJ)

School of Chemistry, The University of Sydney, NSW 2006, Australia; Australian Research Council Centre of Excellence for Innovations in Peptide and Protein Science, The University of Sydney, NSW 2006, Australia; The University of Sydney Nano Institute (Sydney Nano), The University of Sydney, NSW 2006, Australia. Electronic address: elizabeth.new@sydney.edu.au.

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