Factors associated with mortality in patients hospitalized for COVID-19 admitted to a tertiary hospital in Lambayeque, Peru, during the first wave of the pandemic.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 13 10 2022
accepted: 15 04 2023
medline: 15 5 2023
pubmed: 11 5 2023
entrez: 11 5 2023
Statut: epublish

Résumé

COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread worldwide, becoming a long-term pandemic. To analyze the factors associated with mortality in patients hospitalized for COVID-19 in a tertiary hospital in the Lambayeque region of Peru. A retrospective cohort study of patients with a diagnosis of COVID-19, hospitalized in a hospital in northern Peru, was conducted from March to September 2020. Of the 297 patients studied, 69% were women, the mean age was 63.99 years (SD = ±15.33 years). Hypertension was the most frequent comorbidity (36.67%), followed by diabetes mellitus (24.67%) and obesity (8.33%). The probability of survival at 3 days of ICU stay was 65.3%, at 7 days 24.2%, and 0% on day 14. Risk factors associated with mortality in patients hospitalized for COVID-19 are age, male sex, tachypnea, low systolic blood pressure, low peripheral oxygen saturation, impaired renal function, elevated IL-6 and elevated D-dimer. Mortality in hospitalized patients with COVID-19 was 51.18 per 100 persons, Mortality was found to be associated with hypertension, type of infiltrating, and sepsis.

Identifiants

pubmed: 37167338
doi: 10.1371/journal.pone.0285133
pii: PONE-D-22-28266
pmc: PMC10174592
doi:

Banques de données

figshare
['10.6084/m9.figshare.21664172.v1']

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0285133

Informations de copyright

Copyright: © 2023 Aguirre-Milachay et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Edwin Aguirre-Milachay (E)

Servicio de Geriatría, Departamento de Medicina, Hospital Nacional Almanzor Aguinaga Asenjo, Chiclayo, Peru.
Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.

Darwin A León-Figueroa (DA)

Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.
Emerge, Unidad de Investigación en Enfermedades Emergentes y Cambio Climático, Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.

Marisella Chumán-Sánchez (M)

Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.
Sociedad Científica de Estudiantes de Medicina Veritas (SCIEMVE), Chiclayo, Perú.

Luccio Romani (L)

Facultad de Medicina Humana, Universidad de San Martín de Porres, Chiclayo, Peru.
Emerge, Unidad de Investigación en Enfermedades Emergentes y Cambio Climático, Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.

Fernando M Runzer-Colmenares (FM)

CHANGE Research Working Group, Carrera de Medicina Humana, Universidad Científica del Sur, Lima, Peru.

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Classifications MeSH