Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice.

Mice Animals Resveratrol / pharmacology Sarcopenia / drug therapy Sirtuin 1 / metabolism Muscle, Skeletal / metabolism Aging Myocytes, Cardiac / metabolism Hypertrophy Stilbenes / pharmacology
Autophagy Cardiomyocyte hypertrophy Resveratrol Sarcopenia Sirt1

Journal

Journal of pharmacological sciences
ISSN: 1347-8648
Titre abrégé: J Pharmacol Sci
Pays: Japan
ID NLM: 101167001

Informations de publication

Date de publication:
Jun 2023
Historique:
received: 14 11 2022
revised: 05 04 2023
accepted: 10 04 2023
medline: 15 5 2023
pubmed: 12 5 2023
entrez: 11 5 2023
Statut: ppublish

Résumé

Aging is associated with impairment of multiple organs, including skeletal muscle and heart. In this study, we investigated whether resveratrol, an activator of an NAD

Identifiants

DOI: 10.1016/j.jphs.2023.04.001 PMID: 37169475
pubmed: 37169475
pii: S1347-8613(23)00022-1
doi: 10.1016/j.jphs.2023.04.001
pii:
doi:

Substances chimiques

Resveratrol Q369O8926L
Sirtuin 1 EC 3.5.1.-
Stilbenes 0
Sirt1 protein, mouse EC 3.5.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112-122

Informations de copyright

Copyright © 2023 The Authors. Production and hosting by Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Competing interests The authors declare no competing interests.

Auteurs

Ryusuke Hosoda (R)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Ryuta Nakashima (R)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Masaki Yano (M)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Naotoshi Iwahara (N)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Seidai Asakura (S)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Iyori Nojima (I)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Yukika Saga (Y)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Risa Kunimoto (R)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Yoshiyuki Horio (Y)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan.

Atsushi Kuno (A)

Department of Pharmacology, Sapporo Medical University School of Medicine, Japan. Electronic address: kuno@sapmed.ac.jp.

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Classifications MeSH

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questionsmedicales.fr › Eucaryotes › Animaux › Resveratrol, a SIRT1 activator, attenuates...
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questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Sirtuines › Sirtuine-1 › Resveratrol, a SIRT1 activator, attenuates...
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questionsmedicales.fr › États, signes et symptômes pathologiques › États anatomopathologiques › Hypertrophie › Resveratrol, a SIRT1 activator, attenuates...
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